Recombinant Human IL-3 Protein

SARS-CoV-2 superinfection in CD14+ monocytes with latent human cytomegalovirus (HCMV) promotes inflammatory cascade
Authors: Payen, SH;Adhikari, K;Petereit, J;Uppal, T;Rossetto, CC;Verma, SC;
Virus research
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1
Authors: Johnson, D;Colijn, S;Richee, J;Yano, J;Burns, M;Davis, AE;Pham, VN;Saric, A;Jain, A;Yin, Y;Castranova, D;Melani, M;Fujita, M;Grainger, S;Bonifacino, JS;Weinstein, BM;Stratman, AN;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing
Authors: Capin, J;Harrison, A;Raele, RA;Yadav, SKN;Baiwir, D;Mazzucchelli, G;Quinton, L;Satchwell, TJ;Toye, AM;Schaffitzel, C;Berger, I;Aulicino, F;
Nucleic acids research
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
Authors: Wang, P;Zhang, Y;Xiang, R;Yang, J;Xu, Y;Deng, T;Zhou, W;Wang, C;Xiao, X;Wang, S;
Cancer research
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Complete absence of GLUT1 does not impair human terminal erythroid differentiation
Authors: Freire, CM;King, NR;Dzieciatkowska, M;Stephenson, D;Moura, PL;Dobbe, JGG;Streekstra, GJ;D'Alessandro, A;Toye, AM;Satchwell, TJ;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SH2 domain protein E and ABL signaling regulate blood vessel size
Authors: Schumacher, JA;Wright, ZA;Rufin Florat, D;Anand, SK;Dasyani, M;Batta, SPR;Laverde, V;Ferrari, K;Klimkaite, L;Bredemeier, NO;Gurung, S;Koller, GM;Aguera, KN;Chadwick, GP;Johnson, RD;Davis, GE;Sumanas, S;
PLoS genetics
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Triptolide inhibits the proinflammatory potential of myeloid-derived suppressor cells via reducing Arginase-1 in rheumatoid arthritis
Authors: Zhao, Z;Huang, H;Ke, S;Deng, B;Wang, YX;Xu, N;Peng, A;Han, G;Liang, E;He, X;He, Q;Ke, PF;Huang, XZ;He, M;
International immunopharmacology
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Anti-TIM3 chimeric antigen receptor-natural killer cells from engineered induced pluripotent stem cells effectively target acute myeloid leukemia cells
Authors: Klaihmon, P;Luanpitpong, S;Kang, X;Issaragrisil, S;
Cancer cell international
Species: Human
Sample Types: Whole Cells, Embryoid Bodies
Applications: Bioassay

Synergistic roles of DYRK1A and GATA1 in trisomy 21 megakaryopoiesis
Authors: Sit, YT;Takasaki, K;An, HH;Xiao, Y;Hurtz, C;Gearhart, P;Zhang, Z;Gadue, P;French, D;Chou, ST;
JCI insight
Species: Human
Sample Types: Whole Cells, Transduced Whole Cells
Applications: Bioassay

Human cellular model systems of ?-thalassemia enable in-depth analysis of disease phenotype
Authors: Daniels, DE;Ferrer-Vicens, I;Hawksworth, J;Andrienko, TN;Finnie, EM;Bretherton, NS;Ferguson, DCJ;Oliveira, ASF;Szeto, JA;Wilson, MC;Brewin, JN;Frayne, J;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Factors Influencing Marker Expressions of Cultured Human Cord Blood-Derived Mast Cells
Authors: Alimohammadi, S;Masuda-Kuroki, K;Szöll?si, AG;Di Nardo, A;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9
Authors: Vahsen, BF;Nalluru, S;Morgan, GR;Farrimond, L;Carroll, E;Xu, Y;Cramb, KML;Amein, B;Scaber, J;Katsikoudi, A;Candalija, A;Carcolé, M;Dafinca, R;Isaacs, AM;Wade-Martins, R;Gray, E;Turner, MR;Cowley, SA;Talbot, K;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses
Authors: Sulczewski, FB;Maqueda-Alfaro, RA;Alcántara-Hernández, M;Perez, OA;Saravanan, S;Yun, TJ;Seong, D;Arroyo Hornero, R;Raquer-McKay, HM;Esteva, E;Lanzar, ZR;Leylek, RA;Adams, NM;Das, A;Rahman, AH;Gottfried-Blackmore, A;Reizis, B;Idoyaga, J;
Nature immunology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages
Authors: Gillan, JL;Chokshi, M;Hardisty, GR;Clohisey Hendry, S;Prasca-Chamorro, D;Robinson, NJ;Lasota, B;Clark, R;Murphy, L;Whyte, MKB;Baillie, JK;Davidson, DJ;Bao, G;Gray, RD;
Science advances
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy
Authors: Shariatzadeh, M;Nagtzaam, NMA;van Vark-van der Zee, L;van Holten-Neelen, C;Verhoeven, AJM;Dehairs, J;Swinnen, JV;Leijten, F;Ten Berge, JC;Ciriano, JPM;Wong, KT;Mulder, M;Leenen, PJM;Dik, WA;
Investigative ophthalmology & visual science
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts
Authors: A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel
Cell Reports, 2023-04-28;42(5):112453.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A
Authors: AA Almad, L Garcia, A Takanohash, A Gagne, W Yang, J Ann McGuir, D French, A Vanderver
Stem Cell Research, 2023-03-26;69(0):103083.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML
Authors: JR James, J Curd, JC Ashworth, M Abuhantash, M Grundy, CH Seedhouse, KP Arkill, AJ Wright, CLR Merry, A Thompson
International Journal of Molecular Sciences, 2023-02-20;24(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression
Authors: S Takase, T Hiroyama, F Shirai, Y Maemoto, A Nakata, M Arata, S Matsuoka, T Sonoda, H Niwa, S Sato, T Umehara, M Shirouzu, Y Nishigaya, T Sumiya, N Hashimoto, R Namie, M Usui, T Ohishi, SI Ohba, M Kawada, Y Hayashi, H Harada, T Yamaguchi, Y Shinkai, Y Nakamura, M Yoshida, A Ito
Nature Communications, 2023-01-12;14(1):23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses
Authors: L Feige, T Kozaki, G Dias de Me, V Guillemot, F Larrous, F Ginhoux, H Bourhy
Viruses, 2022-12-29;15(1):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment
Authors: X Wang, S Cooper, HE Broxmeyer, R Kapur
Leukemia, 2022-12-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
Authors: X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama
Embo Molecular Medicine, 2022-12-01;0(0):e15631.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture
Authors: PY Su, W Lee, J Zernant, SH Tsang, T Nagasaki, B Corneo, R Allikmets
Oncogene, 2022-11-14;65(0):102973.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Improved Sendai viral system for reprogramming to naive pluripotency.
Authors: Kunitomi A, Hirohata R, Arreola V, Osawa M, Kato T, Nomura M, Kawaguchi J, Hara H, Kusano K, Takashima Y, Takahashi K, Fukuda K, Takasu N, Yamanaka S
Cell Rep Methods, 2022-10-17;2(11):100317.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
Authors: N Vilaplana-, V Cuminetti, R Almaghrabi, G Papatzikas, AK Rout, M Jeeves, E González, Y Alyahyawi, A Cunningham, A Erdem, F Schnütgen, M Raghavan, S Potluri, JB Cazier, JJ Schuringa, MAC Reed, L Arranz, UL Günther, P Garcia
Elife, 2022-09-02;11(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells
Authors: YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra
Science Advances, 2022-08-24;8(34):eabn5522.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
Authors: BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, A Katsikoudi, Y Xu, L Farrimond, R Wade-Marti, WS James, MR Turner, SA Cowley, K Talbot
Scientific Reports, 2022-07-23;12(1):12606.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder
Authors: IB Kim, T Lee, J Lee, J Kim, S Lee, IG Koh, JH Kim, JY An, H Lee, WK Kim, YS Ju, Y Cho, SJ Yu, SA Kim, M Oh, DW Han, E Kim, JK Choi, HJ Yoo, JH Lee
Oncogene, 2022-07-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
Authors: S Wahlen, F Matthijsse, W Van Loocke, S Taveirne, L Kiekens, E Persyn, E Van Ammel, Z De Vos, S De Munter, P Matthys, F Van Nieuwe, T Taghon, B Vandekerck, P Van Vlierb, G Leclercq
Elife, 2022-07-06;11(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors
Authors: L Liu, A Vujovic, NP Deshpande, S Sathe, G Anande, HTT Chen, J Xu, MD Minden, GW Yeo, A Unnikrishn, KJ Hope, Y Lu
Nature Communications, 2022-07-04;13(1):3833.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells
Authors: BA Krishna, AB Wass, EA Murphy, CM O'Connor
Viruses, 2022-06-12;14(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model
Authors: Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BW Mok, A Thakur, X Ke, P Motallebne, V Nicolaescu, J Chen, CY Ma, X Zhou, S Han, T Han, W Zhang, AY Tan, T Zhang, X Wang, D Xu, J Xiang, A Xu, C Liao, FP Huang, YW Chen, J Na, G Randall, HF Tse, Z Chen, Y Chen, HJ Chen
Nature Communications, 2022-04-19;13(1):2028.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL
Authors: AV Jacobsen, CL Pierotti, KN Lowes, AE Au, Y Zhang, N Etemadi, C Fitzgibbon, WJA Kersten, AL Samson, MF van Delft, DCS Huang, HJ Sabroux, G Lessene, J Silke, JM Murphy
Cell Death & Disease, 2022-04-01;13(4):291.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Generation of an induced pluripotent stem cell (iPSC) line from a diabetic patient with glucagon receptor (GCGR) p.W83X mutation
Authors: Y Liu, Y Liu, Y Jia, J Lv, D Sun, Y Yin, N Liu, B Su, G Sun
Stem Cell Research, 2022-03-11;61(0):102745.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL
Authors: G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker
Stem Cell Research, 2021-12-23;59(0):102635.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of an iPSC line (ZZUNEUi021-A) from a hypertrophic cardiomyopathy patient with TNNT2 mutation
Authors: Y Dong, X Li, W Fu, X Tian, G Guo, Y Peng, Y Zhai, J Zhao, Z Ding, X Zhao, J Dong
Stem Cell Research, 2021-12-11;58(0):102622.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera
Authors: C Tipgomut, A Khuhapinan, MC Wilson, S Poldee, KJ Heesom, C Metheetrai, O Sripichai, C Mitrpant, J Frayne, K Trakarnsan
Scientific Reports, 2021-11-18;11(1):22483.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients
Authors: AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles
Cells, 2021-11-10;10(11):.

Generation of two human induced pluripotent stem cell lines from a patient with complete androgen insensitivity syndrome with a hemizygous single nucleotide variant in the androgen receptor (AR) gene
Authors: GB Schwartz, H Kubo, MM Laronda
Stem Cell Research, 2021-06-30;55(0):102441.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity
Authors: G Iannello, A Patel, D Sirabella, B Corneo, V Thaker
Stem Cell Research, 2021-06-21;54(0):102432.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
Authors: S Simón Serr, M Tavecchio, A Grönberg, W Sime, M Jemaà, S Moss, MA Gregory, P Gallay, E Elmér, MJ Hansson, R Massoumi
Cancers, 2021-06-18;13(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Base editing of haematopoietic stem cells rescues sickle cell disease in mice
Authors: GA Newby, JS Yen, KJ Woodard, T Mayuranath, CR Lazzarotto, Y Li, H Sheppard-T, SN Porter, Y Yao, K Mayberry, KA Everette, Y Jang, CJ Podracky, E Thaman, C Lechauve, A Sharma, JM Henderson, MF Richter, KT Zhao, SM Miller, T Wang, LW Koblan, AP McCaffrey, JF Tisdale, TA Kalfa, SM Pruett-Mil, SQ Tsai, MJ Weiss, DR Liu
Nature, 2021-06-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of two human induced pluripotent stem cell (hiPSC) lines derived from unrelated Marfan Syndrome patients
Authors: J Borsoi, M Morato-Mar, F de Araújo, L Assis Pere, LE Farinha-Ar, R Delgado Sa, AB Alvarez Pe, L Veiga Pere
Stem Cell Research, 2021-05-25;54(0):102407.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification
Authors: S Matsuo, Y Nishinaka-, Y Kazuki, M Oshimura, T Nakahata, A Niwa, MK Saito
PLoS ONE, 2021-03-29;16(3):e0247595.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A computer-guided design tool to increase the efficiency of cellular conversions
Authors: S Jung, E Appleton, M Ali, GM Church, A Del Sol
Nature Communications, 2021-03-12;12(1):1659.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
Authors: AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, GM Muscato, RH Klein, K Ballotti, S Liu, CE Harris, A Galvin, M Malsch, D Dale, JM Gansner, TA Nakano, A Bertuch, A Vlachos, JM Lipton, P Castillo, J Connelly, J Churpek, JR Edwards, N Hijiya, RH Ho, I Hofmann, JN Huang, S Keel, A Lamble, BW Lau, M Norkin, E Stieglitz, W Stock, K Walkovich, S Boettcher, C Brendel, MD Fleming, SM Davies, EA Weller, C Bahl, SL Carter, A Shimamura, RC Lindsley
Nature Communications, 2021-02-26;12(1):1334.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets
Authors: T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynow, C Leslie, EP Papapetrou
Cell Stem Cell, 2021-02-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
Authors: P Gonzalez-M, M Romano, H Yan, R Deshmukh, J Papoin, L Oburoglu, M Daumur, AS Dumé, I Phadke, C Mongellaz, X Qu, PN Bories, M Fontenay, X An, V Dardalhon, M Sitbon, VS Zimmermann, PG Gallagher, S Tardito, L Blanc, N Mohandas, N Taylor, S Kinet
Cell Reports, 2021-02-02;34(5):108723.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes
Authors: MAE Rab, BA van Oirsch, PA Kosinski, J Hixon, K Johnson, V Chubukov, L Dang, G Pasterkamp, S van Straat, WW van Soling, EJ van Beers, C Kung, R van Wijk
Haematologica, 2021-01-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2
Authors: S Chen, L Yang, B Nilsson-Pa, Y Han, F Jaffré, J Zhu, P Wang, T Zhang, D Redmond, S Houghton, R Møller, D Hoagland, S Horiuchi, J Acklin, J Lim, Y Bram, C Richardson, V Chandar, A Borczuk, Y Huang, J Xiang, D Ho, R Schwartz, B tenOever, T Evans
Res Sq, 2020-11-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/&beta-thalassemia patient
Authors: K Trakarnsan, C Tipgomut, C Metheetrai, M Wattanapan, A Khuhapinan, S Poldee, R Kurita, Y Nakamura, C Srisawat, J Frayne
Sci Rep, 2020-10-08;10(1):16798.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
Authors: R Leylek, M Alcántara-, JM Granja, M Chavez, K Perez, OR Diaz, R Li, AT Satpathy, HY Chang, J Idoyaga
Cell Rep, 2020-09-22;32(12):108180.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
Res Sq, 2020-09-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells
Authors: S Riccetti, A Sinigaglia, G Desole, N Nowotny, M Trevisan, L Barzon
Viruses, 2020-08-12;12(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency
Authors: BA Krishna, AB Wass, CM O'Connor
Proc. Natl. Acad. Sci. U.S.A., 2020-08-11;117(34):20860-20867.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype
Authors: N Thornton, V Karamatic, L Tilley, CA Green, CL Tay, RE Griffiths, BK Singleton, F Spring, P Walser, AG Alattar, B Jones, R Laundy, JR Storry, M Möller, L Wall, R Charlewood, CM Westhoff, C Lomas-Fran, V Yahalom, U Feick, A Seltsam, B Mayer, ML Olsson, DJ Anstee
Nat Commun, 2020-07-16;11(1):3569.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles
Authors: PR Norden, Z Sun, GE Davis
PLoS ONE, 2020-06-22;15(6):e0235116.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020-06-19;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition
Authors: X Xiao, P Liu, D Li, Z Xia, P Wang, X Zhang, M Liu, L Liao, B Jiao, R Ren
J Hematol Oncol, 2020-06-18;13(1):80.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
Authors: J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomano, A Zviran, AG Deslaurier, N Dusaj, SD Nimer, C Leslie, DA Landau, MG Kharas, EP Papapetrou
Cell Rep, 2020-06-02;31(9):107688.
Species: Human
Sample Types:
Applications: Cell Culture

Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development
Authors: Carissa Dege, Katherine H. Fegan, J. Philip Creamer, Melissa M. Berrien-Elliott, Stephanie A. Luff, Darren Kim et al.
Developmental Cell
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE
Authors: M Meinders, D Shoemark, JGG Dobbe, GJ Streekstra, J Frayne, AM Toye
Mol Ther Methods Clin Dev, 2020-04-01;17(0):822-830.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization
Authors: CD Lemke-Milt, SE Blackwell, C Yin, AE Krug, AJ Morris, AM Krieg, GJ Weiner
J. Immunol., 2020-01-17;204(5):1386-1394.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
Authors: VA Balaji Rag, M Anwar, MZ Akhter, A Chavez, Y Mao, V Natarajan, S Lakshmikan, M Chrzanowsk, AZ Dudek, L Claesson-W, JK Kitajewski, KK Wary, AB Malik, D Mehta
Cell Rep, 2019-12-10;29(11):3472-3487.e4.
Species: Human
Sample Types: Whole Cells

Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population
Authors: R Leylek, M Alcántara-, Z Lanzar, A Lüdtke, OA Perez, B Reizis, J Idoyaga
Cell Rep, 2019-12-10;29(11):3736-3750.e8.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models
Authors: AT Stefka, D Johnson, S Rosebeck, JH Park, Y Nakamura, AJ Jakubowiak
Cancer Med, 2019-11-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
Authors: J Grajcarek, J Monlong, Y Nishinaka-, M Nakamura, M Nagai, S Matsuo, D Lougheed, H Sakurai, MK Saito, G Bourque, K Woltjen
Nat Commun, 2019-10-24;10(1):4856.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system
Authors: JP Ruiz, G Chen, JJ Haro Mora, K Keyvanfar, C Liu, J Zou, J Beers, H Bloomer, H Qanash, N Uchida, JF Tisdale, M Boehm, A Larochelle
Stem Cell Res, 2019-10-15;41(0):101600.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand
Authors: WR Proto, SV Siegel, S Dankwa, W Liu, A Kemp, S Marsden, ZA Zenonos, S Unwin, PM Sharp, GJ Wright, BH Hahn, MT Duraisingh, JC Rayner
Nat Commun, 2019-10-04;10(1):4512.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders
Authors: N Uchida, MM Hsieh, L Raines, JJ Haro-Mora, S Demirci, AC Bonifacino, AE Krouse, ME Metzger, RE Donahue, JF Tisdale
Nat Commun, 2019-10-02;10(1):4479.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance
Authors: M Ly, S Rentas, A Vujovic, N Wong, S Moreira, J Xu, N Holzapfel, S Bhatia, D Tran, MD Minden, JS Draper, KJ Hope
Cancer Res., 2019-09-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia
Authors: MD McKenzie, M Ghisi, EP Oxley, S Ngo, L Cimmino, C Esnault, R Liu, JM Salmon, CC Bell, N Ahmed, M Erlichster, MT Witkowski, GJ Liu, M Chopin, A Dakic, E Simankowic, G Pomilio, T Vu, P Krsmanovic, S Su, L Tian, TM Baldwin, DA Zalcenstei, L DiRago, S Wang, D Metcalf, RW Johnstone, BA Croker, GI Lancaster, AJ Murphy, SH Naik, SL Nutt, V Pospisil, T Schroeder, M Wall, MA Dawson, AH Wei, H de Thé, ME Ritchie, J Zuber, RA Dickins
Cell Stem Cell, 2019-08-01;25(2):258-272.e9.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients
Authors: M Nasri, M Ritter, P Mir, B Dannenmann, N Aghaallaei, D Amend, V Makaryan, Y Xu, B Fletcher, R Bernhard, I Steiert, K Hahnel, J Berger, I Koch, B Sailer, K Hipp, C Zeidler, M Klimiankou, B Bajoghli, DC Dale, K Welte, J Skokowa
Haematologica, 2019-06-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lipocalin 2: A New Antimicrobial in Mast Cells
Authors: YL Chang, Z Wang, S Igawa, JE Choi, T Werbel, A Di Nardo
Int J Mol Sci, 2019-05-14;20(10):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells
Authors: M Ruiz-Gutie, ÖV Bölükba??, G Alexe, AG Kotini, K Ballotti, CE Joyce, DW Russell, K Stegmaier, K Myers, CD Novina, EP Papapetrou, A Shimamura
JCI Insight, 2019-04-30;5(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation
Authors: K Trakarnsan, D Ferguson, DE Daniels, RE Griffiths, MC Wilson, KE Mordue, A Gartner, TN Andrienko, A Calvert, A Condie, A McCahill, JC Mountford, AM Toye, DJ Anstee, J Frayne
Stem Cell Res Ther, 2019-04-29;10(1):130.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
Cell Rep, 2019-04-09;27(2):599-615.e12.
Species: Human
Sample Types: cell culture
Applications: Differentiation, Differentiation

The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids
Authors: AK Seneviratn, M Xu, JJA Henao, VA Fajardo, Z Hao, V Voisin, GW Xu, R Hurren, S Kim, N MacLean, X Wang, M Gronda, D Jeyaraju, Y Jitkova, T Ketela, M Mullokando, D Sharon, G Thomas, R Chouinard-, JR Hawley, C Schafer, HL Yau, Z Khuchua, A Aman, R Al-Awar, A Gross, SM Claypool, R Bazinet, M Lupien, S Chan, DD De Carvalh, MD Minden, GD Bader, KD Stark, P LeBlanc, AD Schimmer
Cell Stem Cell, 2019-03-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
Cell Stem Cell, 2019-03-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans
Authors: SL Taylor, J Hogwood, W Guo, EA Yates, JE Turnbull
Sci Rep, 2019-02-25;9(1):2679.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection
Authors: S Vangeti, J Gertow, M Yu, S Liu, F Baharom, S Scholz, D Friberg, M Starkhamma, A Ahlberg, A Smed-Sören
J. Immunol., 2019-02-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I
Authors: M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue
Stem Cell Res, 2019-02-12;36(0):101406.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling
Authors: P Potirat, M Wattanapan, V Viprakasit, P Kheolamai, S Issaragris
Stem Cell Res, 2018-12-14;34(0):101344.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Downregulation of TREM-like transcript-1 and collagen receptor ?2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia
Authors: AC Glembotsky, D Sliwa, D Bluteau, N Balayn, CP Marin Oyar, A Raimbault, M Bordas, N Droin, I Pirozhkova, V Washington, NP Goette, RF Marta, R Favier, H Raslova, PG Heller
Haematologica, 2018-12-13;104(6):1244-1255.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optimization of an erythroid culture system to reduce the cost of in vitro production of red blood cells
Authors: S Poldee, C Metheetrai, S Nugoolsuks, J Frayne, K Trakarnsan
MethodsX, 2018-11-30;5(0):1626-1632.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells
Authors: A Hyder, S Ehnert, F Fändrich, H Ungefroren
Stem Cells Int, 2018-10-04;2018(0):4271875.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A)
Authors: N Brookhouse, P Zhang, R Caselli, JJ Kim, DA Brafman
Stem Cell Res, 2018-09-21;32(0):145-149.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin.
Authors: Karina T Barretto, Calvin M Swanson, Christopher L Nguyen, Douglas S Annis, Stephane J Esnault, Deane F Mosher, Mats W Johansson
PLoS ONE, 2018-07-26;0(0):1932-6203.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
Authors: Y Heshmati, S Kharazi, G Türköz, D Chang, E Kamali Dol, J Boström, A Krstic, T Boukoura, E Wagner, N Kadri, R Månsson, M Altun, H Qian, J Walfridsso
Sci Rep, 2018-07-25;8(1):11202.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia
Authors: J Zhang, Z Xiang, PA Malaviarac, Y Yan, NJ Baltz, PD Emanuel, YL Liu
Cell. Signal., 2018-06-28;50(0):72-79.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

STK3 is a therapeutic target for a subset of acute myeloid leukemias
Authors: A Camgoz, M Paszkowski, S Satpathy, M Wermke, MV Hamann, M von Bonin, C Choudhary, S Knapp, F Buchholz
Oncotarget, 2018-05-22;9(39):25458-25473.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of Human Induced Pluripotent Stem Cells Using a Defined, Feeder-Free Reprogramming System.
Authors: Park S, Mostoslavsky G
Curr Protoc Stem Cell Biol, 2018-05-04;45(1):e48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach
Authors: R Berndt, L Hummitzsch, K He beta, M Albrecht, K Zitta, R Rusch, B Sarras, A Bayer, J Cremer, F Faendrich, J Gro beta
Stem Cell Res Ther, 2018-04-27;9(1):117.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement
Authors: JM Orengo, AR Radin, V Kamat, A Badithe, LH Ben, BL Bennett, S Zhong, D Birchard, A Limnander, A Rafique, J Bautista, A Kostic, D Newell, X Duan, MC Franklin, W Olson, T Huang, NA Gandhi, L Lipsich, N Stahl, NJ Papadopoul, AJ Murphy, GD Yancopoulo
Nat Commun, 2018-04-12;9(1):1421.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development
Authors: M Cesana, MH Guo, D Cacchiarel, L Wahlster, J Barragan, S Doulatov, LT Vo, B Salvatori, C Trapnell, K Clement, P Cahan, KM Tsanov, PM Sousa, B Tazon-Vega, A Bolondi, FM Giorgi, A Califano, JL Rinn, A Meissner, JN Hirschhorn, GQ Daley
Cell Stem Cell, 2018-04-05;22(4):575-588.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment
Authors: S Kotha, S Sun, A Adams, B Hayes, KT Phong, R Nagao, JA Reems, D Gao, B Torok-Stor, JA López, Y Zheng
PLoS ONE, 2018-04-04;13(4):e0195082.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality
Authors: CM Ferrer, M Alders, AV Postma, S Park, MA Klein, M Cetinbas, E Pajkrt, A Glas, S van Koning, VM Christoffe, MMAM Mannens, L Knegt, JP Etchegaray, RI Sadreyev, JM Denu, G Mostoslavs, MC van Maarle, R Mostoslavs
Genes Dev., 2018-03-19;32(5):373-388.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model
Authors: K Schmitt, P Charlins, M Veselinovi, L Kinner-Bib, S Hu, J Curlin, L Remling-Mu, KE Olson, T Aboellail, R Akkina
Virology, 2018-01-06;515(0):235-242.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells
Authors: M Carretta, AZ Brouwers-V, M Bosman, SJ Horton, JHA Martens, E Vellenga, JJ Schuringa
PLoS ONE, 2017-12-14;12(12):e0189102.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes
Authors: A Palau, AK Garz, J Diesch, A Zwick, R Malinverni, V Valero, K Lappin, R Casquero, A Lennartsso, J Zuber, T Navarro, KI Mills, KS Götze, M Buschbeck
Oncotarget, 2017-12-01;8(70):115002-115017.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain
Authors: RHP Wilbers, DR van Raaij, LB Westerhof, J Bakker, G Smant, A Schots
PLoS ONE, 2017-10-10;12(10):e0186317.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments
Authors: S Radecke, K Schwarz, F Radecke
Mol. Ther., 2017-09-15;26(1):115-131.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
Cell Rep, 2017-08-15;20(7):1597-1608.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis
Authors: L Butcher, M Ahluwalia, T Örd, J Johnston, RH Morris, E Kiss-Toth, T Örd, JD Erusalimsk
Sci Rep, 2017-07-27;7(1):6684.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC Induced Thrombocytopenia
Authors: H Zhao, S Gulesseria, SK Ganesan, J Ou, K Morrison, Z Zeng, V Robles, J Snyder, L Do, H Aviña, S Karki, DR Stover, F Doñate
Mol. Cancer Ther., 2017-06-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
Nat Commun, 2017-05-25;8(0):15380.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise
Authors: H Zhao, S Gulesseria, MC Malinao, S Kumar-Gane, J Song, MS Chang, MM Williams, Z Zeng, M Mattie, BA Mendelsohn, DR Stover, F Doñate
Mol. Cancer Ther., 2017-05-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease
Authors: J Huang, A Khan, BC Au, DL Barber, L López-Vásq, NL Prokopishy, M Boutin, M Rothe, JW Rip, M Abaoui, MS Nagree, S Dworski, A Schambach, A Keating, ML West, J Klassen, PV Turner, S Sirrs, CA Rupar, C Auray-Blai, R Foley, JA Medin
Mol Ther Methods Clin Dev, 2017-05-12;5(0):241-258.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mechanistic Correlates of Clinical Responses to Omalizumab in the Setting of Oral Immunotherapy for Milk Allergy
Authors: PA Frischmeye, M Masilamani, W Gu, E Brittain, R Wood, J Kim, K Nadeau, KM Jarvinen, A Grishin, R Lindblad, HA Sampson
J. Allergy Clin. Immunol., 2017-04-13;0(0):.
Species: Human
Sample Types: Whole Blood
Applications: Bioassay

Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency
Authors: JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia
Cell Rep, 2017-04-04;19(1):20-35.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity
Authors: DC Thomas, S Clare, JM Sowerby, M Pardo, JK Juss, DA Goulding, L van der We, D Storistean, A Prakash, M Espéli, S Flint, JC Lee, K Hoenderdos, L Kane, K Harcourt, S Mukhopadhy, Y Umrania, R Antrobus, JA Nathan, DJ Adams, A Bateman, JS Choudhary, PA Lyons, AM Condliffe, ER Chilvers, G Dougan, KG Smith
J. Exp. Med, 2017-03-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD)
Authors: E Varga, C Nemes, I Bock, Z Táncos, S Berzsenyi, G Lévay, V Román, J Kobolák, A Dinnyés
Stem Cell Res, 2017-03-18;21(0):19-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells
Authors: K Trakarnsan, RE Griffiths, MC Wilson, A Blair, TJ Satchwell, M Meinders, N Cogan, S Kupzig, R Kurita, Y Nakamura, AM Toye, DJ Anstee, J Frayne
Nat Commun, 2017-03-14;8(0):14750.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement
Authors: E Schuh, A Musumeci, FS Thaler, S Laurent, JW Ellwart, R Hohlfeld, A Krug, E Meinl
J. Immunol, 2017-03-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML
Authors: SU Liyanage, R Hurren, V Voisin, G Bridon, X Wang, C Xu, N MacLean, TP Siriwarden, M Gronda, D Yehudai, S Sriskantha, D Avizonis, A Shamas-Din, MD Minden, GD Bader, R Laposa, AD Schimmer
Blood, 2017-03-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
J. Immunol, 2017-03-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption
Authors: CY Chiu, SC Su, WL Fan, SH Lai, MH Tsai, SH Chen, KS Wong, WH Chung
Sci Rep, 2017-02-24;7(0):43469.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
Cell Stem Cell, 2017-02-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
Authors: Ivan Carcamo-Or
Cell Stem Cell, 2016-12-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia
Oncogene, 2016-12-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML
Mol Ther Methods Clin Dev, 2016-12-07;3(0):16074.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta
Authors: Amber N Stratman
Development, 2016-12-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells
PLoS ONE, 2016-11-03;11(11):e0165949.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes
Immunology, 2016-09-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
Cell Biosci, 2016-08-30;6(1):50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors
Sci Rep, 2016-08-30;6(0):32149.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A New Glucocerebrosidase Chaperone Reduces ?-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism
J Neurosci, 2016-07-13;36(28):7441-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts
Blood, 2016-03-24;127(23):2879-89.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation.
Authors: Isabela Pedroza-Pa, Divya Shah, Anna Domogala, Martha Luevano, Michael Blundell, Nicola Jackson, Adrian Thrasher, Alejandro Madrigal, Aurore Saudemont
Scientific Reports, 2016-02-26;0(0):2045-2322.
Species: Xenograft
Sample Types: In Vivo
Applications: In Vivo

Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 degrees C.
Authors: Shima T, Iwasaki H, Yamauchi T, Kadowaki M, Kiyosuke M, Mochimaru T, Takenaka K, Miyamoto T, Akashi K, Teshima T
Bone Marrow Transplant, 2015-06-22;50(9):1195-200.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia.
Authors: Park I, Mundy-Bosse B, Whitman S, Zhang X, Warner S, Bearss D, Blum W, Marcucci G, Caligiuri M
Leukemia, 2015-06-19;29(12):2382-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prospectively Isolated Human Bone Marrow Cell-Derived MSCs Support Primitive Human CD34-Negative Hematopoietic Stem Cells.
Authors: Matsuoka Y, Nakatsuka R, Sumide K, Kawamura H, Takahashi M, Fujioka T, Uemura Y, Asano H, Sasaki Y, Inoue M, Ogawa H, Takahashi T, Hino M, Sonoda Y
Stem Cells, 2015-05-01;33(5):1554-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy.
Authors: Baldwin K, Urbinati F, Romero Z, Campo-Fernandez B, Kaufman M, Cooper A, Masiuk K, Hollis R, Kohn D
Stem Cells, 2015-05-01;33(5):1532-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML).
Authors: Jiang X, Lim C, Li Z, Lee P, Yatim S, Guan P, Li J, Zhou J, Pan J, Chng W, Chai C, Yu Q
PLoS ONE, 2015-04-30;10(4):e0122983.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells.
Authors: Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M
Stem Cells, 2015-04-01;33(4):1142-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues.
Authors: Patterson, Scott D, Rossi, John M, Paweletz, Katherin, Fitzpatrick, V Dan, Begley, C Glenn, Busse, Leigh, Elliott, Steve, McCaffery, Ian
PLoS ONE, 2015-03-25;10(3):e0122149.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation.
Authors: Baharom F, Thomas S, Bieder A, Hellmer M, Volz J, Sandgren K, McInerney G, Karlsson Hedestam G, Mellman I, Smed-Sorensen A
J Immunol, 2015-03-23;194(9):4422-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24).
Authors: Dyer, Kimberly, Rosenberg, Helene F
PLoS ONE, 2015-03-16;10(3):e0118887.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-beta.
Authors: Ungefroren H, Hyder A, Hinz H, Groth S, Lange H, El-Sayed K, Ehnert S, Nussler A, Fandrich F, Gieseler F
PLoS ONE, 2015-02-23;10(2):e0118097.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay

Suppression of basophil FcvarepsilonRI activation by serum from active chronic idiopathic/spontaneous urticaria (CIU/CSU) subjects.
Authors: Sterba P, Hamilton R, Saini S
J Invest Dermatol, 2015-02-03;135(5):1454-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M
J Virol, 2015-01-21;89(7):3859-69.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells.
Authors: Purushothaman P, Thakker S, Verma S
J Virol, 2014-12-31;89(6):3093-111.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.
Authors: Gallagher K, Joshi A, Carson W, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman E, Henke P, Hogaboam C, Burant C, Kunkel S
Diabetes, 2014-11-03;64(4):1420-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice.
Authors: Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, Cherkas A, Tang X, Qin X
Mol Ther, 2014-10-20;23(2):339-51.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Neutralizing antibodies inhibit HIV-1 infection of plasmacytoid dendritic cells by an FcgammaRIIa independent mechanism and do not diminish cytokines production.
Authors: Lederle A, Su B, Holl V, Penichon J, Schmidt S, Decoville T, Laumond G, Moog C
Sci Rep, 2014-08-18;4(0):5845.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased IFN-alpha-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-alpha production.
Authors: Xia C, Peng R, Chernatynskaya A, Yuan L, Carter C, Valentine J, Sobel E, Atkinson M, Clare-Salzler M
J Immunol, 2014-06-27;193(3):1024-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity.
Authors: Lin A, Burrascano C, Pettersson P, Ibanez C, Gruber H, Jolly D
J Virol, 2014-06-25;88(17):10066-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gene transfer properties and structural modeling of human stem cell-derived AAV.
Authors: Smith, Laura J, Ul-Hasan, Taihra, Carvaines, Sarah K, Van Vliet, Kim, Yang, Ethel, Wong, Kamehame, Agbandje-McKenna, Mavis, Chatterjee, Saswati
Mol Ther, 2014-06-13;22(9):1625-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity.
Authors: Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Wang, Xiaoming, Goard, Carolyn, Jhas, Bozhena, Schimmer, Aaron D
PLoS ONE, 2014-05-28;9(5):e95281.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins.
Authors: Yang C, French A, Goh P, Pagnamenta A, Mettananda S, Taylor J, Knight S, Nathwani A, Roberts D, Watt S, Carpenter L
Br J Haematol, 2014-05-16;166(3):435-48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells.
Authors: Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S
Stem Cells, 2014-05-01;32(5):1337-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NADPH oxidase-independent formation of extracellular DNA traps by basophils.
Authors: Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S
J Immunol, 2014-04-25;192(11):5314-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic reprogramming induces the expansion of cord blood stem cells.
Authors: Chaurasia P, Gajzer D, Schaniel C, D'Souza S, Hoffman R
J Clin Invest, 2014-04-24;124(6):2378-95.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline.
Authors: Drewes J, Szeto G, Engle E, Liao Z, Shearer G, Zink M, Graham D
PLoS ONE, 2014-04-14;9(4):e94375.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia.
Authors: Williams M, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, Chapman K, McAndrew R, Thomas A, Spence A, Gibson B, Graham G, Halsey C
Blood, 2014-04-03;123(20):3116-27.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stress hematopoiesis is regulated by the Kruppel-like transcription factor ZBP-89.
Authors: Li X, Romain R, Park D, Scadden D, Merchant J, Arnaout M
Stem Cells, 2014-03-01;32(3):791-801.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells.
Authors: Jensen B, Frandsen P, Raaby E, Schiotz P, Skov P, Poulsen L
J Leukoc Biol, 2014-02-03;95(6):893-901.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.
Authors: van Wilgenburg, Bonnie, Moore, Michael, James, William, Cowley, Sally A
PLoS ONE, 2014-01-22;9(1):e86071.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
Authors: Smith A, Bowers S, Stratman A, Davis G
PLoS ONE, 2013-12-31;8(12):e85147.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.
Authors: Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, Hussein K, Zeidler C, Welte K, Skokowa J
Blood, 2013-12-18;123(8):1239-49.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells.
Authors: Thanunchai, Maytawan, Kanrai, Pumaree, Wiboon-Ut, Suwimon, Puthavathana, Pilaipan, Hongeng, Suradej, Thitithanyanont, Arunee
PLoS ONE, 2013-12-10;8(12):e81805.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MHC class II expression in human basophils: induction and lack of functional significance.
Authors: Voskamp A, Prickett S, Mackay F, Rolland J, O'Hehir R
PLoS ONE, 2013-12-09;8(12):e81777.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa.
Authors: Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J
J Invest Dermatol, 2013-12-06;134(5):1246-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CCK8 negatively regulates the TLR9-induced activation of human peripheral blood pDCs by targeting TRAF6 signaling.
Authors: Jia X, Cong B, Zhang J, Li H, Liu W, Chang H, Dong M, Ma C
Eur J Immunol, 2013-12-02;44(2):489-99.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells.
Authors: Liu, Suiyang, Yin, Li, Stroopinsky, Dina, Rajabi, Hasan, Puissant, Alexandr, Stegmaier, Kimberly, Avigan, David, Kharbanda, Surender, Kufe, Donald, Stone, Richard
Blood, 2013-11-26;123(5):734-42.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells.
Authors: Takahashi, M, Matsuoka, Y, Sumide, K, Nakatsuka, R, Fujioka, T, Kohno, H, Sasaki, Y, Matsui, K, Asano, H, Kaneko, K, Sonoda, Y
Leukemia, 2013-11-05;28(6):1308-15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.
Authors: Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, Hadland B, Bernstein I, Collins J, Zon L, Daley G
Cell Stem Cell, 2013-10-03;13(4):459-70.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib.
Authors: Einwallner E, Jaeger E, Mitterbauer-Hohendanner G, Bilban M, Simonitsch-Klupp I, Steiner I, Pernicka E, Hoermann G, Herndlhofer S, Sillaber C, Valent P, Schwarzinger I
Stem Cells Dev, 2013-09-04;22(23):3043-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
Haematologica, 2013-08-23;99(1):19-27.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis.
Authors: Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S
J Immunol, 2013-03-18;190(8):3959-66.
Species: Human
Sample Types: Plasma
Applications: Bioassay

Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.
Authors: Yu, Jianhua, Peng, Yong, Wu, Lai-Chu, Xie, Zhiliang, Deng, Youcai, Hughes, Tiffany, He, Shun, Mo, XiaoKui, Chiu, Ming, Wang, Qi-En, He, Xiaoming, Liu, Shujun, Grever, Michael, Chan, Kenneth, Liu, Zhongfa
PLoS ONE, 2013-02-13;8(2):e55934.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells.
Authors: Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, Chan R, Bahner I, Gersuk V, Wang X, Gjertson D, Baltimore D, Witte O, Economou J, Ribas A, Kohn D
Mol Ther, 2013-02-05;21(5):1044-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neurotensin and CRH interactions augment human mast cell activation.
Authors: Alysandratos K, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, Critchfield A, Theoharides T
PLoS ONE, 2012-11-14;7(11):e48934.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia.
BMC Cancer, 2012-09-26;12(0):431.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.
Blood Cancer J, 2012-09-07;2(0):e87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene.
Authors: Li Q, Ramirez-Bergeron D, Dunwoodie S, Yang Y
J Biol Chem, 2012-07-03;287(34):29088-100.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chronic immune activation in HIV-1 infection contributes to reduced interferon alpha production via enhanced CD40:CD40 ligand interaction.
Authors: Donhauser N, Pritschet K, Helm M, Harrer T, Schuster P, Ries M, Bischof G, Vollmer J, Smola S, Schmidt B
PLoS ONE, 2012-03-21;7(3):e33925.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ETV6-RUNX1 promotes survival of early B lineage progenitor cells via a dysregulated erythropoietin receptor.
Authors: Torrano V, Procter J, Cardus P
Blood, 2011-09-07;118(18):4910-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.
Authors: Bond E, Liang F, Sandgren KJ, Smed-Sorensen A, Bergman P, Brighenti S, Adams WC, Betemariam SA, Rangaka MX, Lange C, Wilkinson RJ, Andersson J, Lore K
J. Invest. Dermatol., 2011-08-18;132(1):114-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.
Authors: Niwa A, Heike T, Umeda K
PLoS ONE, 2011-07-27;6(7):e22261.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
Authors: Uchida N, Hsieh MM, Hayakawa J, Madison C, Washington KN, Tisdale JF
Gene Ther., 2011-05-05;18(11):1078-86.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma.
Authors: Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, Escudier B, Azzarone B, Caignard A
Oncogene, 2011-01-24;30(23):2622-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome).
Authors: Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, McElmurry R, Eide C, Orchard P, Kyba M, Osborn M, Lund T, Wagner J, Daley G, Blazar B
Blood, 2010-10-29;117(3):839-47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamic interaction networks in a hierarchically organized tissue.
Authors: Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW
Mol. Syst. Biol., 2010-10-05;6(0):417.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage.
Authors: Gupta N, Barhanpurkar AP, Tomar GB
J. Immunol., 2010-07-19;185(4):2261-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells.
Authors: Ghirelli C, Zollinger R, Soumelis V
Blood, 2010-04-09;115(24):5037-40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation.
Authors: Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE
Blood, 2009-10-12;114(24):5091-101.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma.
Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D
Int. J. Cancer, 2009-09-01;125(5):1092-101.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
Proc. Natl. Acad. Sci. U.S.A., 2009-05-29;106(24):9826-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008-05-27;36(8):1035-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
Exp. Hematol., 2008-05-01;36(5):545-558.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15.
Authors: McCullar V, Oostendorp R, Panoskaltsis-Mortari A, Yun G, Lutz CT, Wagner JE, Miller JS
Exp. Hematol., 2008-03-04;36(5):598-608.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
Authors: Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
Stem Cells, 2007-02-01;25(2):490-9.
Species: Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
Authors: Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
Exp. Hematol., 2006-10-01;34(10):1312-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD48 is an allergen and IL-3-induced activation molecule on eosinophils.
Authors: Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, Levi-Schaffer F
J. Immunol., 2006-07-01;177(1):77-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis.
Authors: Vassina EM, Yousefi S, Simon D, Zwicky C, Conus S, Simon HU
Eur. J. Immunol., 2006-07-01;36(7):1975-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells.
Authors: Yokoi H, Myers A, Matsumoto K, Crocker PR, Saito H, Bochner BS
Allergy, 2006-06-01;61(6):769-76.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.
Authors: Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, Nagasawa T, Nakamura Y
Exp. Hematol., 2006-06-01;34(6):760-9.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells.
Authors: Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, Zini R, Salati S, Tagliafico E, Manfredini R, Grande A, Ferrari S
Cell Death Differ., 2006-02-03;13(10):1686-96.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines.
Authors: Femenia F, Arock M, Leriche L, Delouis C, Millet G, Ben Hamouda N, Cote M, Alliot A, Lilin T, Pinton A, Iannucceli N, Parodi AL, Boireau P
Life Sci., 2005-07-01;77(7):808-23.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay

Growth hormone-induced stimulation of multilineage human hematopoiesis.
Authors: Hanley MB, Napolitano LA, McCune JM
Stem Cells, 2005-06-13;23(8):1170-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Thrombospondin 1, produced by endothelial cells under the action of erythropoietin, stimulates thymidine incorporation into erythroid cells and counteracts the inhibitory action of insulin-like growth factor binding protein 3.
Authors: Congote LF, DiFalco MR, Gibbs BF
Cytokine, 2005-03-23;30(5):248-53.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
J. Immunol., 2004-09-01;173(5):3482-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis.
Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N
Blood, 2003-09-25;103(3):1089-98.
Species: Human
Sample Types: Serum
Applications: SDS-Page

Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells.
Authors: Bug G, Rossmanith T, Henschler R, Kunz-Schughart LA, Schroder B, Kampfmann M, Kreutz M, Hoelzer D, Ottmann OG
J. Leukoc. Biol., 2002-10-01;72(4):837-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prospective isolation of human clonogenic common myeloid progenitors.
Authors: Manz MG, 107325, Miyamoto T, Akashi K, Weissman IL
Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases, 2002-08-22;99(18):11872-7.
Species: Human
Sample Types:
Applications: Bioassay

Expression of functional interleukin-3 receptors on Hodgkin and Reed-Sternberg cells.
Authors: Aldinucci D, 2019, Poletto D, Gloghini A, Nanni P, Degan M, Perin T, Ceolin P, Rossi FM, Gattei V, Carbone A, Pinto A
439, 2002-02-01;160(2):585-96.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.
Authors: Shih CC, Hu MC, Hu J
Blood, 2000-03-15;95(6):1957-66.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model.
Authors: Gomez-Navarro J, ¯&h~²@á, Contreras JL, Arafat W, Jiang XL, Krisky D, Oligino T, Marconi P, Hubbard B, Glorioso JC, Curiel DT, Thomas JM
2000-01-01;7(1):43-52.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
Blood, 1996-09-15;88(6):2013-25.
Species: Human
Sample Types:
Applications: Bioassay

Proliferating dendritic cell progenitors in human blood.
Authors: Romani N, Gruner S, Brang D, Kampgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch P, Steinman R, Schuler G
J Exp Med, 1994-07-01;180(1):83-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay