Recombinant Human IL-3 Protein

GMP Version Available: 203-GMP
GMP
Analyzed by SEC-MALS

Carrier Free

Catalog # Availability Size / Price Qty
203-IL-010/CF
203-IL-050/CF
203-IL-250/CF
203-IL-500/CF
203-IL-01M/CF
203-IL-100/CF

With Carrier

Catalog # Availability Size / Price Qty
203-IL-010
203-IL-050
203-IL-100
203-IL-250
203-IL-500
203-IL-01M

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Recombinant Human IL‑3 Protein SEC-MALS.
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Product Details
Citations (222)
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Recombinant Human IL-3 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is 0.02-0.1 ng/mL.
Source
E. coli-derived human IL-3 protein
Ala20-Phe152, with and without an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Ala20 and Met
Predicted Molecular Mass
15 kDa

Product Datasheets

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203-IL (with carrier)

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203-IL/CF (carrier free)

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

203-IL

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

203-IL/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

SEC-MALS View Larger

Recombinant Human IL-3 Protein (Catalog # 203-IL) has a molecular weight (MW) of 14.6 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer.

Bioactivity Recombinant Human IL-3 Protein Bioactivity View Larger

Recombinant Human IL-3 (Catalog # 203-IL) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED50 for this effect is 0.02-0.1 ng/mL.

SDS-PAGE Recombinant Human IL-3 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Human IL-3 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-3

Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages. Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor, P-cell stimulating factor, burst promoting activity, multi-colony stimulating factor, thy-1 inducing factor and WEHI-3 growth factor. In addition to activated T cells, other cell types such as human thymic epithelial cells, activated murine mast cells, murine keratinocytes and neurons/astrocytes can also produce IL-3. At the amino acid sequence level, mature human and murine IL-3 share only 29% sequence identity. Consistent with this lack of homology, IL-3 activity is highly species-specific and human IL-3 does not show activity on murine cells.

IL-3 exerts its biological activities through binding to specific cell surface receptors. The high affinity receptor responsible for IL-3 signaling is composed of at least two subunits, an IL-3 specific alpha chain which binds IL-3 with low affinity and a common beta chain that is shared by the IL-5 and GM-CSF high-affinity receptors. Although the beta chain itself does not bind IL-3, it confers high-affinity IL-3 binding in the presence of the  alpha chain. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils and various myeloid leukemic cells.

Long Name
Interleukin 3
Entrez Gene IDs
3562 (Human); 16187 (Mouse); 24495 (Rat)
Alternate Names
Hematopoietic growth factor; IL3; IL-3; IL-3MGC79398; interleukin 3 (colony-stimulating factor, multiple); interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MCGFMGC79399; MULTI-CSF; multilineage-colony-stimulating factor; Multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor

Citations for Recombinant Human IL-3 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

222 Citations: Showing 1 - 10
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  1. Inflammatory responses revealed through HIV infection of microglia-containing cerebral organoids
    Authors: Narasipura, SD;Zayas, JP;Ash, MK;Reyes, AF;Shull, T;Gambut, S;Szczerkowski, JLA;McKee, C;Schneider, JR;Lorenzo-Redondo, R;Al-Harthi, L;Mamede, JI;
    Journal of neuroinflammation
    Species: Human
    Sample Types: Whole Cells, Organoid
    Applications: Bioassay
  2. Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages
    Authors: Pickering, S;Wilson, H;Bravo, E;Perera, MR;Seow, J;Graham, C;Almeida, N;Fotopoulos, L;Williams, T;Moitra, A;Winstone, H;Nissen, TAD;Galão, RP;Snell, LB;Doores, KJ;Malim, MH;Neil, SJD;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate
    Authors: Demirci, S;Zeng, J;Palchaudhuri, R;Wu, C;Abraham, DM;Hayal, TB;Essawi, K;Nguyen, MA;Stasula, U;Chu, R;Leonard, A;Porter, SN;Khan, MBN;Hinojosa, G;Uchida, N;Hong, S;Lazzarotto, CR;Neri, NR;da Silva, LF;Pellin, D;Verma, A;Lanieri, L;Bhat, A;Hammond, K;Tate, T;Maitland, SA;Sheikhsaran, F;Bonifacino, AC;Krouse, AE;Linde, NS;Engels, T;Golomb, J;Tsai, SQ;Pruett-Miller, SM;Scadden, DT;Dunbar, CE;Wolfe, SA;Donahue, RE;Olson, LM;Bauer, DE;Tisdale, JF;
    Cell stem cell
    Species: Mouse, Rhesus Macaque
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Evidence for a Role of the Long Non-Coding RNA ITGB2-AS1 in Eosinophil Differentiation and Functions
    Authors: Fettrelet, T;Hosseini, A;Wyss, J;Boros-Majewska, J;Stojkov, D;Yousefi, S;Simon, HU;
    Cells
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Homology-independent targeted insertion-mediated derivation of M1-biased macrophages harbouring Megf10 and CD3? from human pluripotent stem cells
    Authors: Zhen, X;Kim, J;Kang, JS;Choi, BJ;Park, KH;Lee, DS;Hong, SH;Lee, JH;
    EBioMedicine
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cells
    Authors: Kent, GM;Atkins, MH;Lung, B;Nikitina, A;Fernandes, IM;Kwan, JJ;Andrews, TS;MacParland, SA;Keller, GM;Gage, BK;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Human Vascularized Macrophage-Islet Organoids to Model Immune-Mediated Pancreatic ? cell Pyroptosis upon Viral Infection
    Authors: Yang, L;Han, Y;Zhang, T;Dong, X;Ge, J;Roy, A;Zhu, J;Lu, T;Vandana, JJ;de Silva, N;Robertson, CC;Xiang, JZ;Pan, C;Sun, Y;Que, J;Evans, T;Liu, C;Wang, W;Naji, A;Parker, SCJ;Schwartz, RE;Chen, S;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms
    Authors: Landau, S;Zhao, Y;Hamidzada, H;Kent, GM;Okhovatian, S;Lu, RXZ;Liu, C;Wagner, KT;Cheung, K;Shawky, SA;Vosoughi, D;Beroncal, EL;Fernandes, I;Cummins, CL;Andreazza, AC;Keller, GM;Epelman, S;Radisic, M;
    Cell stem cell
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries
    Authors: Abello, J;Yin, Y;Zhao, Y;Maurer, J;Lee, J;Bodell, C;Clevenger, AJ;Burton, Z;Goeckel, ME;Lin, M;Grainger, S;Halabi, CM;Raghavan, SA;Sah, R;Stratman, AN;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model
    Authors: Paul, SK;Oshima, M;Patil, A;Sone, M;Kato, H;Maezawa, Y;Kaneko, H;Fukuyo, M;Rahmutulla, B;Ouchi, Y;Tsujimura, K;Nakanishi, M;Kaneda, A;Iwama, A;Yokote, K;Eto, K;Takayama, N;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. SARS-CoV-2 superinfection in CD14+ monocytes with latent human cytomegalovirus (HCMV) promotes inflammatory cascade
    Authors: Payen, SH;Adhikari, K;Petereit, J;Uppal, T;Rossetto, CC;Verma, SC;
    Virus research
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1
    Authors: Johnson, D;Colijn, S;Richee, J;Yano, J;Burns, M;Davis, AE;Pham, VN;Saric, A;Jain, A;Yin, Y;Castranova, D;Melani, M;Fujita, M;Grainger, S;Bonifacino, JS;Weinstein, BM;Stratman, AN;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing
    Authors: Capin, J;Harrison, A;Raele, RA;Yadav, SKN;Baiwir, D;Mazzucchelli, G;Quinton, L;Satchwell, TJ;Toye, AM;Schaffitzel, C;Berger, I;Aulicino, F;
    Nucleic acids research
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
    Authors: Wang, P;Zhang, Y;Xiang, R;Yang, J;Xu, Y;Deng, T;Zhou, W;Wang, C;Xiao, X;Wang, S;
    Cancer research
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  15. Complete absence of GLUT1 does not impair human terminal erythroid differentiation
    Authors: Freire, CM;King, NR;Dzieciatkowska, M;Stephenson, D;Moura, PL;Dobbe, JGG;Streekstra, GJ;D'Alessandro, A;Toye, AM;Satchwell, TJ;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. SH2 domain protein E and ABL signaling regulate blood vessel size
    Authors: Schumacher, JA;Wright, ZA;Rufin Florat, D;Anand, SK;Dasyani, M;Batta, SPR;Laverde, V;Ferrari, K;Klimkaite, L;Bredemeier, NO;Gurung, S;Koller, GM;Aguera, KN;Chadwick, GP;Johnson, RD;Davis, GE;Sumanas, S;
    PLoS genetics
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Triptolide inhibits the proinflammatory potential of myeloid-derived suppressor cells via reducing Arginase-1 in rheumatoid arthritis
    Authors: Zhao, Z;Huang, H;Ke, S;Deng, B;Wang, YX;Xu, N;Peng, A;Han, G;Liang, E;He, X;He, Q;Ke, PF;Huang, XZ;He, M;
    International immunopharmacology
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  18. Anti-TIM3 chimeric antigen receptor-natural killer cells from engineered induced pluripotent stem cells effectively target acute myeloid leukemia cells
    Authors: Klaihmon, P;Luanpitpong, S;Kang, X;Issaragrisil, S;
    Cancer cell international
    Species: Human
    Sample Types: Whole Cells, Embryoid Bodies
    Applications: Bioassay
  19. Synergistic roles of DYRK1A and GATA1 in trisomy 21 megakaryopoiesis
    Authors: Sit, YT;Takasaki, K;An, HH;Xiao, Y;Hurtz, C;Gearhart, P;Zhang, Z;Gadue, P;French, D;Chou, ST;
    JCI insight
    Species: Human
    Sample Types: Whole Cells, Transduced Whole Cells
    Applications: Bioassay
  20. Human cellular model systems of ?-thalassemia enable in-depth analysis of disease phenotype
    Authors: Daniels, DE;Ferrer-Vicens, I;Hawksworth, J;Andrienko, TN;Finnie, EM;Bretherton, NS;Ferguson, DCJ;Oliveira, ASF;Szeto, JA;Wilson, MC;Brewin, JN;Frayne, J;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Factors Influencing Marker Expressions of Cultured Human Cord Blood-Derived Mast Cells
    Authors: Alimohammadi, S;Masuda-Kuroki, K;Szöll?si, AG;Di Nardo, A;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9
    Authors: Vahsen, BF;Nalluru, S;Morgan, GR;Farrimond, L;Carroll, E;Xu, Y;Cramb, KML;Amein, B;Scaber, J;Katsikoudi, A;Candalija, A;Carcolé, M;Dafinca, R;Isaacs, AM;Wade-Martins, R;Gray, E;Turner, MR;Cowley, SA;Talbot, K;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses
    Authors: Sulczewski, FB;Maqueda-Alfaro, RA;Alcántara-Hernández, M;Perez, OA;Saravanan, S;Yun, TJ;Seong, D;Arroyo Hornero, R;Raquer-McKay, HM;Esteva, E;Lanzar, ZR;Leylek, RA;Adams, NM;Das, A;Rahman, AH;Gottfried-Blackmore, A;Reizis, B;Idoyaga, J;
    Nature immunology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages
    Authors: Gillan, JL;Chokshi, M;Hardisty, GR;Clohisey Hendry, S;Prasca-Chamorro, D;Robinson, NJ;Lasota, B;Clark, R;Murphy, L;Whyte, MKB;Baillie, JK;Davidson, DJ;Bao, G;Gray, RD;
    Science advances
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy
    Authors: Shariatzadeh, M;Nagtzaam, NMA;van Vark-van der Zee, L;van Holten-Neelen, C;Verhoeven, AJM;Dehairs, J;Swinnen, JV;Leijten, F;Ten Berge, JC;Ciriano, JPM;Wong, KT;Mulder, M;Leenen, PJM;Dik, WA;
    Investigative ophthalmology & visual science
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts
    Authors: A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel
    Cell Reports, 2023-04-28;42(5):112453.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A
    Authors: AA Almad, L Garcia, A Takanohash, A Gagne, W Yang, J Ann McGuir, D French, A Vanderver
    Stem Cell Research, 2023-03-26;69(0):103083.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML
    Authors: JR James, J Curd, JC Ashworth, M Abuhantash, M Grundy, CH Seedhouse, KP Arkill, AJ Wright, CLR Merry, A Thompson
    International Journal of Molecular Sciences, 2023-02-20;24(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression
    Authors: S Takase, T Hiroyama, F Shirai, Y Maemoto, A Nakata, M Arata, S Matsuoka, T Sonoda, H Niwa, S Sato, T Umehara, M Shirouzu, Y Nishigaya, T Sumiya, N Hashimoto, R Namie, M Usui, T Ohishi, SI Ohba, M Kawada, Y Hayashi, H Harada, T Yamaguchi, Y Shinkai, Y Nakamura, M Yoshida, A Ito
    Nature Communications, 2023-01-12;14(1):23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses
    Authors: L Feige, T Kozaki, G Dias de Me, V Guillemot, F Larrous, F Ginhoux, H Bourhy
    Viruses, 2022-12-29;15(1):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment
    Authors: X Wang, S Cooper, HE Broxmeyer, R Kapur
    Leukemia, 2022-12-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  32. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    Authors: X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama
    Embo Molecular Medicine, 2022-12-01;0(0):e15631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  33. Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture
    Authors: PY Su, W Lee, J Zernant, SH Tsang, T Nagasaki, B Corneo, R Allikmets
    Oncogene, 2022-11-14;65(0):102973.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Improved Sendai viral system for reprogramming to naive pluripotency.
    Authors: Kunitomi A, Hirohata R, Arreola V, Osawa M, Kato T, Nomura M, Kawaguchi J, Hara H, Kusano K, Takashima Y, Takahashi K, Fukuda K, Takasu N, Yamanaka S
    Cell Rep Methods, 2022-10-17;2(11):100317.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
    Authors: N Vilaplana-, V Cuminetti, R Almaghrabi, G Papatzikas, AK Rout, M Jeeves, E González, Y Alyahyawi, A Cunningham, A Erdem, F Schnütgen, M Raghavan, S Potluri, JB Cazier, JJ Schuringa, MAC Reed, L Arranz, UL Günther, P Garcia
    Elife, 2022-09-02;11(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells
    Authors: YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra
    Science Advances, 2022-08-24;8(34):eabn5522.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
    Authors: BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, A Katsikoudi, Y Xu, L Farrimond, R Wade-Marti, WS James, MR Turner, SA Cowley, K Talbot
    Scientific Reports, 2022-07-23;12(1):12606.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder
    Authors: IB Kim, T Lee, J Lee, J Kim, S Lee, IG Koh, JH Kim, JY An, H Lee, WK Kim, YS Ju, Y Cho, SJ Yu, SA Kim, M Oh, DW Han, E Kim, JK Choi, HJ Yoo, JH Lee
    Oncogene, 2022-07-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
    Authors: S Wahlen, F Matthijsse, W Van Loocke, S Taveirne, L Kiekens, E Persyn, E Van Ammel, Z De Vos, S De Munter, P Matthys, F Van Nieuwe, T Taghon, B Vandekerck, P Van Vlierb, G Leclercq
    Elife, 2022-07-06;11(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors
    Authors: L Liu, A Vujovic, NP Deshpande, S Sathe, G Anande, HTT Chen, J Xu, MD Minden, GW Yeo, A Unnikrishn, KJ Hope, Y Lu
    Nature Communications, 2022-07-04;13(1):3833.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells
    Authors: BA Krishna, AB Wass, EA Murphy, CM O'Connor
    Viruses, 2022-06-12;14(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model
    Authors: Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BW Mok, A Thakur, X Ke, P Motallebne, V Nicolaescu, J Chen, CY Ma, X Zhou, S Han, T Han, W Zhang, AY Tan, T Zhang, X Wang, D Xu, J Xiang, A Xu, C Liao, FP Huang, YW Chen, J Na, G Randall, HF Tse, Z Chen, Y Chen, HJ Chen
    Nature Communications, 2022-04-19;13(1):2028.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL
    Authors: AV Jacobsen, CL Pierotti, KN Lowes, AE Au, Y Zhang, N Etemadi, C Fitzgibbon, WJA Kersten, AL Samson, MF van Delft, DCS Huang, HJ Sabroux, G Lessene, J Silke, JM Murphy
    Cell Death & Disease, 2022-04-01;13(4):291.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  44. Generation of an induced pluripotent stem cell (iPSC) line from a diabetic patient with glucagon receptor (GCGR) p.W83X mutation
    Authors: Y Liu, Y Liu, Y Jia, J Lv, D Sun, Y Yin, N Liu, B Su, G Sun
    Stem Cell Research, 2022-03-11;61(0):102745.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL
    Authors: G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker
    Stem Cell Research, 2021-12-23;59(0):102635.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Generation of an iPSC line (ZZUNEUi021-A) from a hypertrophic cardiomyopathy patient with TNNT2 mutation
    Authors: Y Dong, X Li, W Fu, X Tian, G Guo, Y Peng, Y Zhai, J Zhao, Z Ding, X Zhao, J Dong
    Stem Cell Research, 2021-12-11;58(0):102622.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera
    Authors: C Tipgomut, A Khuhapinan, MC Wilson, S Poldee, KJ Heesom, C Metheetrai, O Sripichai, C Mitrpant, J Frayne, K Trakarnsan
    Scientific Reports, 2021-11-18;11(1):22483.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients
    Authors: AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles
    Cells, 2021-11-10;10(11):.
  49. Generation of two human induced pluripotent stem cell lines from a patient with complete androgen insensitivity syndrome with a hemizygous single nucleotide variant in the androgen receptor (AR) gene
    Authors: GB Schwartz, H Kubo, MM Laronda
    Stem Cell Research, 2021-06-30;55(0):102441.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity
    Authors: G Iannello, A Patel, D Sirabella, B Corneo, V Thaker
    Stem Cell Research, 2021-06-21;54(0):102432.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
    Authors: S Simón Serr, M Tavecchio, A Grönberg, W Sime, M Jemaà, S Moss, MA Gregory, P Gallay, E Elmér, MJ Hansson, R Massoumi
    Cancers, 2021-06-18;13(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Base editing of haematopoietic stem cells rescues sickle cell disease in mice
    Authors: GA Newby, JS Yen, KJ Woodard, T Mayuranath, CR Lazzarotto, Y Li, H Sheppard-T, SN Porter, Y Yao, K Mayberry, KA Everette, Y Jang, CJ Podracky, E Thaman, C Lechauve, A Sharma, JM Henderson, MF Richter, KT Zhao, SM Miller, T Wang, LW Koblan, AP McCaffrey, JF Tisdale, TA Kalfa, SM Pruett-Mil, SQ Tsai, MJ Weiss, DR Liu
    Nature, 2021-06-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Generation of two human induced pluripotent stem cell (hiPSC) lines derived from unrelated Marfan Syndrome patients
    Authors: J Borsoi, M Morato-Mar, F de Araújo, L Assis Pere, LE Farinha-Ar, R Delgado Sa, AB Alvarez Pe, L Veiga Pere
    Stem Cell Research, 2021-05-25;54(0):102407.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification
    Authors: S Matsuo, Y Nishinaka-, Y Kazuki, M Oshimura, T Nakahata, A Niwa, MK Saito
    PLoS ONE, 2021-03-29;16(3):e0247595.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. A computer-guided design tool to increase the efficiency of cellular conversions
    Authors: S Jung, E Appleton, M Ali, GM Church, A Del Sol
    Nature Communications, 2021-03-12;12(1):1659.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  56. Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
    Authors: AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, GM Muscato, RH Klein, K Ballotti, S Liu, CE Harris, A Galvin, M Malsch, D Dale, JM Gansner, TA Nakano, A Bertuch, A Vlachos, JM Lipton, P Castillo, J Connelly, J Churpek, JR Edwards, N Hijiya, RH Ho, I Hofmann, JN Huang, S Keel, A Lamble, BW Lau, M Norkin, E Stieglitz, W Stock, K Walkovich, S Boettcher, C Brendel, MD Fleming, SM Davies, EA Weller, C Bahl, SL Carter, A Shimamura, RC Lindsley
    Nature Communications, 2021-02-26;12(1):1334.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets
    Authors: T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynow, C Leslie, EP Papapetrou
    Cell Stem Cell, 2021-02-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
    Authors: P Gonzalez-M, M Romano, H Yan, R Deshmukh, J Papoin, L Oburoglu, M Daumur, AS Dumé, I Phadke, C Mongellaz, X Qu, PN Bories, M Fontenay, X An, V Dardalhon, M Sitbon, VS Zimmermann, PG Gallagher, S Tardito, L Blanc, N Mohandas, N Taylor, S Kinet
    Cell Reports, 2021-02-02;34(5):108723.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes
    Authors: MAE Rab, BA van Oirsch, PA Kosinski, J Hixon, K Johnson, V Chubukov, L Dang, G Pasterkamp, S van Straat, WW van Soling, EJ van Beers, C Kung, R van Wijk
    Haematologica, 2021-01-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  60. SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2
    Authors: S Chen, L Yang, B Nilsson-Pa, Y Han, F Jaffré, J Zhu, P Wang, T Zhang, D Redmond, S Houghton, R Møller, D Hoagland, S Horiuchi, J Acklin, J Lim, Y Bram, C Richardson, V Chandar, A Borczuk, Y Huang, J Xiang, D Ho, R Schwartz, B tenOever, T Evans
    Res Sq, 2020-11-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/&beta-thalassemia patient
    Authors: K Trakarnsan, C Tipgomut, C Metheetrai, M Wattanapan, A Khuhapinan, S Poldee, R Kurita, Y Nakamura, C Srisawat, J Frayne
    Sci Rep, 2020-10-08;10(1):16798.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
    Authors: R Leylek, M Alcántara-, JM Granja, M Chavez, K Perez, OR Diaz, R Li, AT Satpathy, HY Chang, J Idoyaga
    Cell Rep, 2020-09-22;32(12):108180.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
    Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
    Res Sq, 2020-09-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells
    Authors: S Riccetti, A Sinigaglia, G Desole, N Nowotny, M Trevisan, L Barzon
    Viruses, 2020-08-12;12(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency
    Authors: BA Krishna, AB Wass, CM O'Connor
    Proc. Natl. Acad. Sci. U.S.A., 2020-08-11;117(34):20860-20867.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype
    Authors: N Thornton, V Karamatic, L Tilley, CA Green, CL Tay, RE Griffiths, BK Singleton, F Spring, P Walser, AG Alattar, B Jones, R Laundy, JR Storry, M Möller, L Wall, R Charlewood, CM Westhoff, C Lomas-Fran, V Yahalom, U Feick, A Seltsam, B Mayer, ML Olsson, DJ Anstee
    Nat Commun, 2020-07-16;11(1):3569.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles
    Authors: PR Norden, Z Sun, GE Davis
    PLoS ONE, 2020-06-22;15(6):e0235116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
    Cell Stem Cell, 2020-06-19;27(1):125-136.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition
    Authors: X Xiao, P Liu, D Li, Z Xia, P Wang, X Zhang, M Liu, L Liao, B Jiao, R Ren
    J Hematol Oncol, 2020-06-18;13(1):80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
    Authors: J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomano, A Zviran, AG Deslaurier, N Dusaj, SD Nimer, C Leslie, DA Landau, MG Kharas, EP Papapetrou
    Cell Rep, 2020-06-02;31(9):107688.
    Species: Human
    Sample Types:
    Applications: Cell Culture
  71. Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development
    Authors: Carissa Dege, Katherine H. Fegan, J. Philip Creamer, Melissa M. Berrien-Elliott, Stephanie A. Luff, Darren Kim et al.
    Developmental Cell
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE
    Authors: M Meinders, D Shoemark, JGG Dobbe, GJ Streekstra, J Frayne, AM Toye
    Mol Ther Methods Clin Dev, 2020-04-01;17(0):822-830.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  73. Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization
    Authors: CD Lemke-Milt, SE Blackwell, C Yin, AE Krug, AJ Morris, AM Krieg, GJ Weiner
    J. Immunol., 2020-01-17;204(5):1386-1394.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
    Cell Stem Cell, 2020;27(1):125-136.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
    Authors: VA Balaji Rag, M Anwar, MZ Akhter, A Chavez, Y Mao, V Natarajan, S Lakshmikan, M Chrzanowsk, AZ Dudek, L Claesson-W, JK Kitajewski, KK Wary, AB Malik, D Mehta
    Cell Rep, 2019-12-10;29(11):3472-3487.e4.
    Species: Human
    Sample Types: Whole Cells
  76. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population
    Authors: R Leylek, M Alcántara-, Z Lanzar, A Lüdtke, OA Perez, B Reizis, J Idoyaga
    Cell Rep, 2019-12-10;29(11):3736-3750.e8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  77. Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models
    Authors: AT Stefka, D Johnson, S Rosebeck, JH Park, Y Nakamura, AJ Jakubowiak
    Cancer Med, 2019-11-12;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  78. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
    Authors: J Grajcarek, J Monlong, Y Nishinaka-, M Nakamura, M Nagai, S Matsuo, D Lougheed, H Sakurai, MK Saito, G Bourque, K Woltjen
    Nat Commun, 2019-10-24;10(1):4856.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system
    Authors: JP Ruiz, G Chen, JJ Haro Mora, K Keyvanfar, C Liu, J Zou, J Beers, H Bloomer, H Qanash, N Uchida, JF Tisdale, M Boehm, A Larochelle
    Stem Cell Res, 2019-10-15;41(0):101600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  80. Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand
    Authors: WR Proto, SV Siegel, S Dankwa, W Liu, A Kemp, S Marsden, ZA Zenonos, S Unwin, PM Sharp, GJ Wright, BH Hahn, MT Duraisingh, JC Rayner
    Nat Commun, 2019-10-04;10(1):4512.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  81. Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders
    Authors: N Uchida, MM Hsieh, L Raines, JJ Haro-Mora, S Demirci, AC Bonifacino, AE Krouse, ME Metzger, RE Donahue, JF Tisdale
    Nat Commun, 2019-10-02;10(1):4479.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  82. Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance
    Authors: M Ly, S Rentas, A Vujovic, N Wong, S Moreira, J Xu, N Holzapfel, S Bhatia, D Tran, MD Minden, JS Draper, KJ Hope
    Cancer Res., 2019-09-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia
    Authors: MD McKenzie, M Ghisi, EP Oxley, S Ngo, L Cimmino, C Esnault, R Liu, JM Salmon, CC Bell, N Ahmed, M Erlichster, MT Witkowski, GJ Liu, M Chopin, A Dakic, E Simankowic, G Pomilio, T Vu, P Krsmanovic, S Su, L Tian, TM Baldwin, DA Zalcenstei, L DiRago, S Wang, D Metcalf, RW Johnstone, BA Croker, GI Lancaster, AJ Murphy, SH Naik, SL Nutt, V Pospisil, T Schroeder, M Wall, MA Dawson, AH Wei, H de Thé, ME Ritchie, J Zuber, RA Dickins
    Cell Stem Cell, 2019-08-01;25(2):258-272.e9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  84. CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients
    Authors: M Nasri, M Ritter, P Mir, B Dannenmann, N Aghaallaei, D Amend, V Makaryan, Y Xu, B Fletcher, R Bernhard, I Steiert, K Hahnel, J Berger, I Koch, B Sailer, K Hipp, C Zeidler, M Klimiankou, B Bajoghli, DC Dale, K Welte, J Skokowa
    Haematologica, 2019-06-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Lipocalin 2: A New Antimicrobial in Mast Cells
    Authors: YL Chang, Z Wang, S Igawa, JE Choi, T Werbel, A Di Nardo
    Int J Mol Sci, 2019-05-14;20(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  86. Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells
    Authors: M Ruiz-Gutie, ÖV Bölükba??, G Alexe, AG Kotini, K Ballotti, CE Joyce, DW Russell, K Stegmaier, K Myers, CD Novina, EP Papapetrou, A Shimamura
    JCI Insight, 2019-04-30;5(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  87. Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation
    Authors: K Trakarnsan, D Ferguson, DE Daniels, RE Griffiths, MC Wilson, KE Mordue, A Gartner, TN Andrienko, A Calvert, A Condie, A McCahill, JC Mountford, AM Toye, DJ Anstee, J Frayne
    Stem Cell Res Ther, 2019-04-29;10(1):130.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
    Cell Rep, 2019-04-09;27(2):599-615.e12.
    Species: Human
    Sample Types: cell culture
    Applications: Differentiation, Differentiation
  89. The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids
    Authors: AK Seneviratn, M Xu, JJA Henao, VA Fajardo, Z Hao, V Voisin, GW Xu, R Hurren, S Kim, N MacLean, X Wang, M Gronda, D Jeyaraju, Y Jitkova, T Ketela, M Mullokando, D Sharon, G Thomas, R Chouinard-, JR Hawley, C Schafer, HL Yau, Z Khuchua, A Aman, R Al-Awar, A Gross, SM Claypool, R Bazinet, M Lupien, S Chan, DD De Carvalh, MD Minden, GD Bader, KD Stark, P LeBlanc, AD Schimmer
    Cell Stem Cell, 2019-03-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
    Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
    Cell Stem Cell, 2019-03-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans
    Authors: SL Taylor, J Hogwood, W Guo, EA Yates, JE Turnbull
    Sci Rep, 2019-02-25;9(1):2679.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection
    Authors: S Vangeti, J Gertow, M Yu, S Liu, F Baharom, S Scholz, D Friberg, M Starkhamma, A Ahlberg, A Smed-Sören
    J. Immunol., 2019-02-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I
    Authors: M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue
    Stem Cell Res, 2019-02-12;36(0):101406.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling
    Authors: P Potirat, M Wattanapan, V Viprakasit, P Kheolamai, S Issaragris
    Stem Cell Res, 2018-12-14;34(0):101344.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Downregulation of TREM-like transcript-1 and collagen receptor ?2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia
    Authors: AC Glembotsky, D Sliwa, D Bluteau, N Balayn, CP Marin Oyar, A Raimbault, M Bordas, N Droin, I Pirozhkova, V Washington, NP Goette, RF Marta, R Favier, H Raslova, PG Heller
    Haematologica, 2018-12-13;104(6):1244-1255.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Optimization of an erythroid culture system to reduce the cost of in vitro production of red blood cells
    Authors: S Poldee, C Metheetrai, S Nugoolsuks, J Frayne, K Trakarnsan
    MethodsX, 2018-11-30;5(0):1626-1632.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells
    Authors: A Hyder, S Ehnert, F Fändrich, H Ungefroren
    Stem Cells Int, 2018-10-04;2018(0):4271875.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A)
    Authors: N Brookhouse, P Zhang, R Caselli, JJ Kim, DA Brafman
    Stem Cell Res, 2018-09-21;32(0):145-149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin.
    Authors: Karina T Barretto, Calvin M Swanson, Christopher L Nguyen, Douglas S Annis, Stephane J Esnault, Deane F Mosher, Mats W Johansson
    PLoS ONE, 2018-07-26;0(0):1932-6203.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
    Authors: Y Heshmati, S Kharazi, G Türköz, D Chang, E Kamali Dol, J Boström, A Krstic, T Boukoura, E Wagner, N Kadri, R Månsson, M Altun, H Qian, J Walfridsso
    Sci Rep, 2018-07-25;8(1):11202.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia
    Authors: J Zhang, Z Xiang, PA Malaviarac, Y Yan, NJ Baltz, PD Emanuel, YL Liu
    Cell. Signal., 2018-06-28;50(0):72-79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. STK3 is a therapeutic target for a subset of acute myeloid leukemias
    Authors: A Camgoz, M Paszkowski, S Satpathy, M Wermke, MV Hamann, M von Bonin, C Choudhary, S Knapp, F Buchholz
    Oncotarget, 2018-05-22;9(39):25458-25473.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Generation of Human Induced Pluripotent Stem Cells Using a Defined, Feeder-Free Reprogramming System.
    Authors: Park S, Mostoslavsky G
    Curr Protoc Stem Cell Biol, 2018-05-04;45(1):e48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach
    Authors: R Berndt, L Hummitzsch, K He beta, M Albrecht, K Zitta, R Rusch, B Sarras, A Bayer, J Cremer, F Faendrich, J Gro beta
    Stem Cell Res Ther, 2018-04-27;9(1):117.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement
    Authors: JM Orengo, AR Radin, V Kamat, A Badithe, LH Ben, BL Bennett, S Zhong, D Birchard, A Limnander, A Rafique, J Bautista, A Kostic, D Newell, X Duan, MC Franklin, W Olson, T Huang, NA Gandhi, L Lipsich, N Stahl, NJ Papadopoul, AJ Murphy, GD Yancopoulo
    Nat Commun, 2018-04-12;9(1):1421.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development
    Authors: M Cesana, MH Guo, D Cacchiarel, L Wahlster, J Barragan, S Doulatov, LT Vo, B Salvatori, C Trapnell, K Clement, P Cahan, KM Tsanov, PM Sousa, B Tazon-Vega, A Bolondi, FM Giorgi, A Califano, JL Rinn, A Meissner, JN Hirschhorn, GQ Daley
    Cell Stem Cell, 2018-04-05;22(4):575-588.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment
    Authors: S Kotha, S Sun, A Adams, B Hayes, KT Phong, R Nagao, JA Reems, D Gao, B Torok-Stor, JA López, Y Zheng
    PLoS ONE, 2018-04-04;13(4):e0195082.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality
    Authors: CM Ferrer, M Alders, AV Postma, S Park, MA Klein, M Cetinbas, E Pajkrt, A Glas, S van Koning, VM Christoffe, MMAM Mannens, L Knegt, JP Etchegaray, RI Sadreyev, JM Denu, G Mostoslavs, MC van Maarle, R Mostoslavs
    Genes Dev., 2018-03-19;32(5):373-388.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model
    Authors: K Schmitt, P Charlins, M Veselinovi, L Kinner-Bib, S Hu, J Curlin, L Remling-Mu, KE Olson, T Aboellail, R Akkina
    Virology, 2018-01-06;515(0):235-242.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells
    Authors: M Carretta, AZ Brouwers-V, M Bosman, SJ Horton, JHA Martens, E Vellenga, JJ Schuringa
    PLoS ONE, 2017-12-14;12(12):e0189102.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes
    Authors: A Palau, AK Garz, J Diesch, A Zwick, R Malinverni, V Valero, K Lappin, R Casquero, A Lennartsso, J Zuber, T Navarro, KI Mills, KS Götze, M Buschbeck
    Oncotarget, 2017-12-01;8(70):115002-115017.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain
    Authors: RHP Wilbers, DR van Raaij, LB Westerhof, J Bakker, G Smant, A Schots
    PLoS ONE, 2017-10-10;12(10):e0186317.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments
    Authors: S Radecke, K Schwarz, F Radecke
    Mol. Ther., 2017-09-15;26(1):115-131.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
    Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
    Cell Rep, 2017-08-15;20(7):1597-1608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis
    Authors: L Butcher, M Ahluwalia, T Örd, J Johnston, RH Morris, E Kiss-Toth, T Örd, JD Erusalimsk
    Sci Rep, 2017-07-27;7(1):6684.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC Induced Thrombocytopenia
    Authors: H Zhao, S Gulesseria, SK Ganesan, J Ou, K Morrison, Z Zeng, V Robles, J Snyder, L Do, H Aviña, S Karki, DR Stover, F Doñate
    Mol. Cancer Ther., 2017-06-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
    Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
    Nat Commun, 2017-05-25;8(0):15380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise
    Authors: H Zhao, S Gulesseria, MC Malinao, S Kumar-Gane, J Song, MS Chang, MM Williams, Z Zeng, M Mattie, BA Mendelsohn, DR Stover, F Doñate
    Mol. Cancer Ther., 2017-05-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease
    Authors: J Huang, A Khan, BC Au, DL Barber, L López-Vásq, NL Prokopishy, M Boutin, M Rothe, JW Rip, M Abaoui, MS Nagree, S Dworski, A Schambach, A Keating, ML West, J Klassen, PV Turner, S Sirrs, CA Rupar, C Auray-Blai, R Foley, JA Medin
    Mol Ther Methods Clin Dev, 2017-05-12;5(0):241-258.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Mechanistic Correlates of Clinical Responses to Omalizumab in the Setting of Oral Immunotherapy for Milk Allergy
    Authors: PA Frischmeye, M Masilamani, W Gu, E Brittain, R Wood, J Kim, K Nadeau, KM Jarvinen, A Grishin, R Lindblad, HA Sampson
    J. Allergy Clin. Immunol., 2017-04-13;0(0):.
    Species: Human
    Sample Types: Whole Blood
    Applications: Bioassay
  121. Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency
    Authors: JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia
    Cell Rep, 2017-04-04;19(1):20-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity
    Authors: DC Thomas, S Clare, JM Sowerby, M Pardo, JK Juss, DA Goulding, L van der We, D Storistean, A Prakash, M Espéli, S Flint, JC Lee, K Hoenderdos, L Kane, K Harcourt, S Mukhopadhy, Y Umrania, R Antrobus, JA Nathan, DJ Adams, A Bateman, JS Choudhary, PA Lyons, AM Condliffe, ER Chilvers, G Dougan, KG Smith
    J. Exp. Med, 2017-03-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD)
    Authors: E Varga, C Nemes, I Bock, Z Táncos, S Berzsenyi, G Lévay, V Román, J Kobolák, A Dinnyés
    Stem Cell Res, 2017-03-18;21(0):19-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells
    Authors: K Trakarnsan, RE Griffiths, MC Wilson, A Blair, TJ Satchwell, M Meinders, N Cogan, S Kupzig, R Kurita, Y Nakamura, AM Toye, DJ Anstee, J Frayne
    Nat Commun, 2017-03-14;8(0):14750.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement
    Authors: E Schuh, A Musumeci, FS Thaler, S Laurent, JW Ellwart, R Hohlfeld, A Krug, E Meinl
    J. Immunol, 2017-03-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML
    Authors: SU Liyanage, R Hurren, V Voisin, G Bridon, X Wang, C Xu, N MacLean, TP Siriwarden, M Gronda, D Yehudai, S Sriskantha, D Avizonis, A Shamas-Din, MD Minden, GD Bader, R Laposa, AD Schimmer
    Blood, 2017-03-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
    Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
    J. Immunol, 2017-03-06;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption
    Authors: CY Chiu, SC Su, WL Fan, SH Lai, MH Tsai, SH Chen, KS Wong, WH Chung
    Sci Rep, 2017-02-24;7(0):43469.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
    Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
    Cell Stem Cell, 2017-02-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
    Authors: Ivan Carcamo-Or
    Cell Stem Cell, 2016-12-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia
    Oncogene, 2016-12-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML
    Mol Ther Methods Clin Dev, 2016-12-07;3(0):16074.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta
    Authors: Amber N Stratman
    Development, 2016-12-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells
    PLoS ONE, 2016-11-03;11(11):e0165949.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes
    Immunology, 2016-09-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
    Cell Biosci, 2016-08-30;6(1):50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors
    Sci Rep, 2016-08-30;6(0):32149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. A New Glucocerebrosidase Chaperone Reduces ?-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism
    J Neurosci, 2016-07-13;36(28):7441-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts
    Blood, 2016-03-24;127(23):2879-89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation.
    Authors: Isabela Pedroza-Pa, Divya Shah, Anna Domogala, Martha Luevano, Michael Blundell, Nicola Jackson, Adrian Thrasher, Alejandro Madrigal, Aurore Saudemont
    Scientific Reports, 2016-02-26;0(0):2045-2322.
    Species: Xenograft
    Sample Types: In Vivo
    Applications: In Vivo
  141. Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 degrees C.
    Authors: Shima T, Iwasaki H, Yamauchi T, Kadowaki M, Kiyosuke M, Mochimaru T, Takenaka K, Miyamoto T, Akashi K, Teshima T
    Bone Marrow Transplant, 2015-06-22;50(9):1195-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia.
    Authors: Park I, Mundy-Bosse B, Whitman S, Zhang X, Warner S, Bearss D, Blum W, Marcucci G, Caligiuri M
    Leukemia, 2015-06-19;29(12):2382-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Prospectively Isolated Human Bone Marrow Cell-Derived MSCs Support Primitive Human CD34-Negative Hematopoietic Stem Cells.
    Authors: Matsuoka Y, Nakatsuka R, Sumide K, Kawamura H, Takahashi M, Fujioka T, Uemura Y, Asano H, Sasaki Y, Inoue M, Ogawa H, Takahashi T, Hino M, Sonoda Y
    Stem Cells, 2015-05-01;33(5):1554-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy.
    Authors: Baldwin K, Urbinati F, Romero Z, Campo-Fernandez B, Kaufman M, Cooper A, Masiuk K, Hollis R, Kohn D
    Stem Cells, 2015-05-01;33(5):1532-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML).
    Authors: Jiang X, Lim C, Li Z, Lee P, Yatim S, Guan P, Li J, Zhou J, Pan J, Chng W, Chai C, Yu Q
    PLoS ONE, 2015-04-30;10(4):e0122983.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells.
    Authors: Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M
    Stem Cells, 2015-04-01;33(4):1142-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues.
    Authors: Patterson, Scott D, Rossi, John M, Paweletz, Katherin, Fitzpatrick, V Dan, Begley, C Glenn, Busse, Leigh, Elliott, Steve, McCaffery, Ian
    PLoS ONE, 2015-03-25;10(3):e0122149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation.
    Authors: Baharom F, Thomas S, Bieder A, Hellmer M, Volz J, Sandgren K, McInerney G, Karlsson Hedestam G, Mellman I, Smed-Sorensen A
    J Immunol, 2015-03-23;194(9):4422-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24).
    Authors: Dyer, Kimberly, Rosenberg, Helene F
    PLoS ONE, 2015-03-16;10(3):e0118887.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-beta.
    Authors: Ungefroren H, Hyder A, Hinz H, Groth S, Lange H, El-Sayed K, Ehnert S, Nussler A, Fandrich F, Gieseler F
    PLoS ONE, 2015-02-23;10(2):e0118097.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  151. Suppression of basophil FcvarepsilonRI activation by serum from active chronic idiopathic/spontaneous urticaria (CIU/CSU) subjects.
    Authors: Sterba P, Hamilton R, Saini S
    J Invest Dermatol, 2015-02-03;135(5):1454-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  152. High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
    Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M
    J Virol, 2015-01-21;89(7):3859-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells.
    Authors: Purushothaman P, Thakker S, Verma S
    J Virol, 2014-12-31;89(6):3093-111.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.
    Authors: Gallagher K, Joshi A, Carson W, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman E, Henke P, Hogaboam C, Burant C, Kunkel S
    Diabetes, 2014-11-03;64(4):1420-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice.
    Authors: Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, Cherkas A, Tang X, Qin X
    Mol Ther, 2014-10-20;23(2):339-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Neutralizing antibodies inhibit HIV-1 infection of plasmacytoid dendritic cells by an FcgammaRIIa independent mechanism and do not diminish cytokines production.
    Authors: Lederle A, Su B, Holl V, Penichon J, Schmidt S, Decoville T, Laumond G, Moog C
    Sci Rep, 2014-08-18;4(0):5845.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Increased IFN-alpha-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-alpha production.
    Authors: Xia C, Peng R, Chernatynskaya A, Yuan L, Carter C, Valentine J, Sobel E, Atkinson M, Clare-Salzler M
    J Immunol, 2014-06-27;193(3):1024-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity.
    Authors: Lin A, Burrascano C, Pettersson P, Ibanez C, Gruber H, Jolly D
    J Virol, 2014-06-25;88(17):10066-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Gene transfer properties and structural modeling of human stem cell-derived AAV.
    Authors: Smith, Laura J, Ul-Hasan, Taihra, Carvaines, Sarah K, Van Vliet, Kim, Yang, Ethel, Wong, Kamehame, Agbandje-McKenna, Mavis, Chatterjee, Saswati
    Mol Ther, 2014-06-13;22(9):1625-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity.
    Authors: Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Wang, Xiaoming, Goard, Carolyn, Jhas, Bozhena, Schimmer, Aaron D
    PLoS ONE, 2014-05-28;9(5):e95281.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins.
    Authors: Yang C, French A, Goh P, Pagnamenta A, Mettananda S, Taylor J, Knight S, Nathwani A, Roberts D, Watt S, Carpenter L
    Br J Haematol, 2014-05-16;166(3):435-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells.
    Authors: Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S
    Stem Cells, 2014-05-01;32(5):1337-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. NADPH oxidase-independent formation of extracellular DNA traps by basophils.
    Authors: Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S
    J Immunol, 2014-04-25;192(11):5314-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Epigenetic reprogramming induces the expansion of cord blood stem cells.
    Authors: Chaurasia P, Gajzer D, Schaniel C, D'Souza S, Hoffman R
    J Clin Invest, 2014-04-24;124(6):2378-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline.
    Authors: Drewes J, Szeto G, Engle E, Liao Z, Shearer G, Zink M, Graham D
    PLoS ONE, 2014-04-14;9(4):e94375.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia.
    Authors: Williams M, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, Chapman K, McAndrew R, Thomas A, Spence A, Gibson B, Graham G, Halsey C
    Blood, 2014-04-03;123(20):3116-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Stress hematopoiesis is regulated by the Kruppel-like transcription factor ZBP-89.
    Authors: Li X, Romain R, Park D, Scadden D, Merchant J, Arnaout M
    Stem Cells, 2014-03-01;32(3):791-801.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells.
    Authors: Jensen B, Frandsen P, Raaby E, Schiotz P, Skov P, Poulsen L
    J Leukoc Biol, 2014-02-03;95(6):893-901.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.
    Authors: van Wilgenburg, Bonnie, Moore, Michael, James, William, Cowley, Sally A
    PLoS ONE, 2014-01-22;9(1):e86071.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013-12-31;8(12):e85147.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.
    Authors: Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, Hussein K, Zeidler C, Welte K, Skokowa J
    Blood, 2013-12-18;123(8):1239-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells.
    Authors: Thanunchai, Maytawan, Kanrai, Pumaree, Wiboon-Ut, Suwimon, Puthavathana, Pilaipan, Hongeng, Suradej, Thitithanyanont, Arunee
    PLoS ONE, 2013-12-10;8(12):e81805.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. MHC class II expression in human basophils: induction and lack of functional significance.
    Authors: Voskamp A, Prickett S, Mackay F, Rolland J, O'Hehir R
    PLoS ONE, 2013-12-09;8(12):e81777.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  174. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa.
    Authors: Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J
    J Invest Dermatol, 2013-12-06;134(5):1246-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. CCK8 negatively regulates the TLR9-induced activation of human peripheral blood pDCs by targeting TRAF6 signaling.
    Authors: Jia X, Cong B, Zhang J, Li H, Liu W, Chang H, Dong M, Ma C
    Eur J Immunol, 2013-12-02;44(2):489-99.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  176. MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells.
    Authors: Liu, Suiyang, Yin, Li, Stroopinsky, Dina, Rajabi, Hasan, Puissant, Alexandr, Stegmaier, Kimberly, Avigan, David, Kharbanda, Surender, Kufe, Donald, Stone, Richard
    Blood, 2013-11-26;123(5):734-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells.
    Authors: Takahashi, M, Matsuoka, Y, Sumide, K, Nakatsuka, R, Fujioka, T, Kohno, H, Sasaki, Y, Matsui, K, Asano, H, Kaneko, K, Sonoda, Y
    Leukemia, 2013-11-05;28(6):1308-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.
    Authors: Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, Hadland B, Bernstein I, Collins J, Zon L, Daley G
    Cell Stem Cell, 2013-10-03;13(4):459-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib.
    Authors: Einwallner E, Jaeger E, Mitterbauer-Hohendanner G, Bilban M, Simonitsch-Klupp I, Steiner I, Pernicka E, Hoermann G, Herndlhofer S, Sillaber C, Valent P, Schwarzinger I
    Stem Cells Dev, 2013-09-04;22(23):3043-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
    Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
    Haematologica, 2013-08-23;99(1):19-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis.
    Authors: Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S
    J Immunol, 2013-03-18;190(8):3959-66.
    Species: Human
    Sample Types: Plasma
    Applications: Bioassay
  182. Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.
    Authors: Yu, Jianhua, Peng, Yong, Wu, Lai-Chu, Xie, Zhiliang, Deng, Youcai, Hughes, Tiffany, He, Shun, Mo, XiaoKui, Chiu, Ming, Wang, Qi-En, He, Xiaoming, Liu, Shujun, Grever, Michael, Chan, Kenneth, Liu, Zhongfa
    PLoS ONE, 2013-02-13;8(2):e55934.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells.
    Authors: Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, Chan R, Bahner I, Gersuk V, Wang X, Gjertson D, Baltimore D, Witte O, Economou J, Ribas A, Kohn D
    Mol Ther, 2013-02-05;21(5):1044-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Neurotensin and CRH interactions augment human mast cell activation.
    Authors: Alysandratos K, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, Critchfield A, Theoharides T
    PLoS ONE, 2012-11-14;7(11):e48934.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia.
    BMC Cancer, 2012-09-26;12(0):431.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.
    Blood Cancer J, 2012-09-07;2(0):e87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene.
    Authors: Li Q, Ramirez-Bergeron D, Dunwoodie S, Yang Y
    J Biol Chem, 2012-07-03;287(34):29088-100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Chronic immune activation in HIV-1 infection contributes to reduced interferon alpha production via enhanced CD40:CD40 ligand interaction.
    Authors: Donhauser N, Pritschet K, Helm M, Harrer T, Schuster P, Ries M, Bischof G, Vollmer J, Smola S, Schmidt B
    PLoS ONE, 2012-03-21;7(3):e33925.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. ETV6-RUNX1 promotes survival of early B lineage progenitor cells via a dysregulated erythropoietin receptor.
    Authors: Torrano V, Procter J, Cardus P
    Blood, 2011-09-07;118(18):4910-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.
    Authors: Bond E, Liang F, Sandgren KJ, Smed-Sorensen A, Bergman P, Brighenti S, Adams WC, Betemariam SA, Rangaka MX, Lange C, Wilkinson RJ, Andersson J, Lore K
    J. Invest. Dermatol., 2011-08-18;132(1):114-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.
    Authors: Niwa A, Heike T, Umeda K
    PLoS ONE, 2011-07-27;6(7):e22261.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
    Authors: Uchida N, Hsieh MM, Hayakawa J, Madison C, Washington KN, Tisdale JF
    Gene Ther., 2011-05-05;18(11):1078-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma.
    Authors: Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, Escudier B, Azzarone B, Caignard A
    Oncogene, 2011-01-24;30(23):2622-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome).
    Authors: Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, McElmurry R, Eide C, Orchard P, Kyba M, Osborn M, Lund T, Wagner J, Daley G, Blazar B
    Blood, 2010-10-29;117(3):839-47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Dynamic interaction networks in a hierarchically organized tissue.
    Authors: Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW
    Mol. Syst. Biol., 2010-10-05;6(0):417.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage.
    Authors: Gupta N, Barhanpurkar AP, Tomar GB
    J. Immunol., 2010-07-19;185(4):2261-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells.
    Authors: Ghirelli C, Zollinger R, Soumelis V
    Blood, 2010-04-09;115(24):5037-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation.
    Authors: Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE
    Blood, 2009-10-12;114(24):5091-101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma.
    Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D
    Int. J. Cancer, 2009-09-01;125(5):1092-101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
    Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
    Proc. Natl. Acad. Sci. U.S.A., 2009-05-29;106(24):9826-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
    Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
    Exp. Hematol., 2008-05-27;36(8):1035-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
    Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
    Exp. Hematol., 2008-05-01;36(5):545-558.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15.
    Authors: McCullar V, Oostendorp R, Panoskaltsis-Mortari A, Yun G, Lutz CT, Wagner JE, Miller JS
    Exp. Hematol., 2008-03-04;36(5):598-608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007-02-01;25(2):490-9.
    Species: Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
    Authors: Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
    Exp. Hematol., 2006-10-01;34(10):1312-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. CD48 is an allergen and IL-3-induced activation molecule on eosinophils.
    Authors: Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, Levi-Schaffer F
    J. Immunol., 2006-07-01;177(1):77-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis.
    Authors: Vassina EM, Yousefi S, Simon D, Zwicky C, Conus S, Simon HU
    Eur. J. Immunol., 2006-07-01;36(7):1975-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells.
    Authors: Yokoi H, Myers A, Matsumoto K, Crocker PR, Saito H, Bochner BS
    Allergy, 2006-06-01;61(6):769-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.
    Authors: Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, Nagasawa T, Nakamura Y
    Exp. Hematol., 2006-06-01;34(6):760-9.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells.
    Authors: Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, Zini R, Salati S, Tagliafico E, Manfredini R, Grande A, Ferrari S
    Cell Death Differ., 2006-02-03;13(10):1686-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines.
    Authors: Femenia F, Arock M, Leriche L, Delouis C, Millet G, Ben Hamouda N, Cote M, Alliot A, Lilin T, Pinton A, Iannucceli N, Parodi AL, Boireau P
    Life Sci., 2005-07-01;77(7):808-23.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Growth hormone-induced stimulation of multilineage human hematopoiesis.
    Authors: Hanley MB, Napolitano LA, McCune JM
    Stem Cells, 2005-06-13;23(8):1170-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Thrombospondin 1, produced by endothelial cells under the action of erythropoietin, stimulates thymidine incorporation into erythroid cells and counteracts the inhibitory action of insulin-like growth factor binding protein 3.
    Authors: Congote LF, DiFalco MR, Gibbs BF
    Cytokine, 2005-03-23;30(5):248-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
    Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
    J. Immunol., 2004-09-01;173(5):3482-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis.
    Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N
    Blood, 2003-09-25;103(3):1089-98.
    Species: Human
    Sample Types: Serum
    Applications: SDS-Page
  216. Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells.
    Authors: Bug G, Rossmanith T, Henschler R, Kunz-Schughart LA, Schroder B, Kampfmann M, Kreutz M, Hoelzer D, Ottmann OG
    J. Leukoc. Biol., 2002-10-01;72(4):837-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Prospective isolation of human clonogenic common myeloid progenitors.
    Authors: Manz MG, 107325, Miyamoto T, Akashi K, Weissman IL
    Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases, 2002-08-22;99(18):11872-7.
    Species: Human
    Sample Types:
    Applications: Bioassay
  218. Expression of functional interleukin-3 receptors on Hodgkin and Reed-Sternberg cells.
    Authors: Aldinucci D, 2019, Poletto D, Gloghini A, Nanni P, Degan M, Perin T, Ceolin P, Rossi FM, Gattei V, Carbone A, Pinto A
    439, 2002-02-01;160(2):585-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.
    Authors: Shih CC, Hu MC, Hu J
    Blood, 2000-03-15;95(6):1957-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model.
    Authors: Gomez-Navarro J, ¯&h~²@á, Contreras JL, Arafat W, Jiang XL, Krisky D, Oligino T, Marconi P, Hubbard B, Glorioso JC, Curiel DT, Thomas JM
    2000-01-01;7(1):43-52.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
    Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
    Blood, 1996-09-15;88(6):2013-25.
    Species: Human
    Sample Types:
    Applications: Bioassay
  222. Proliferating dendritic cell progenitors in human blood.
    Authors: Romani N, Gruner S, Brang D, Kampgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch P, Steinman R, Schuler G
    J Exp Med, 1994-07-01;180(1):83-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Can I reconstitute Recombinant Human IL-3 Protein (catalog # 203-IL) at a different concentration than recommended?

    • We cannot guarantee the performance if the protein is reconstituted at a different concentration than recommended in the product datasheet. Please contact Technical Service if you have any questions or concerns about reconstitution.

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Recombinant Human IL-3 Protein
By Anonymous on 04/16/2023
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human IL-3 Protein
By Anonymous on 01/01/2022
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human IL-3 Protein
By Meilyn Sylvestre on 11/20/2020
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human IL-3 Protein
By Anonymous on 10/13/2020
Application: Stem/Immune cell maintenance or differentiation

It's good for hematopoietic colony formation.


Recombinant Human IL-3 Protein
By Zhenping Wang on 09/30/2020
Application: CellDiff