RIC8A Antibody

Novus Biologicals | Catalog # NB100-1473

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all RIC8A Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence CLSSDPDSDPD corresponding to C-Terminus according to NP_068751.4.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for RIC8A Antibody

Western Blot: RIC8A Antibody [NB100-1473]

Western Blot: RIC8A Antibody [NB100-1473]

Western Blot: RIC8A Antibody [NB100-1473] - Analysis of RIC8A in human brain lysate (RIPA buffer, 35ug total protein per lane) using this antibody at 1ug/ml. Primary incubated for 1 hour. Detected using chemiluminescence.

Applications for RIC8A Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 70 kDa band observed in human brain lysates (calculated MW of 60.4 kDa band according to NP_068751.4).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RIC8A

RIC8 is a likely orthalog of mouse Synembryn. Synembryns are proteins that positively regulate synaptic transmission. They are actively required to maintain proper activity of the Go to Gq G-protein signalling network, which regulates neurotransmitter secretion in Caenorhabditis elegans by controlling the production and consumption of diacylglycerol. In addition to its role in the adult nervous system, synembryn is required to regulate a subset of centrosome movements in the early C. elegans embryo.

Alternate Names

RIC8, RIC8A resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), synembryn, synembryn-A

Entrez Gene IDs

60626 (Human); 101489 (Mouse)

Gene Symbol

RIC8A

UniProt

NP_068751. (Human)

Additional RIC8A Products

Product Documents for RIC8A Antibody

Certificate of Analysis

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Product Specific Notices for RIC8A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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