RIP140 Antibody

Name: RIP140 Antibody
Brand: Novus Biologicals
SKU: NB110-5122
Price: 399 USD
Availability: InStock
Rating: 3 (1 reviews)

Novus Biologicals | Catalog # NB110-5122

(1)

Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

View all RIP140 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues G(718) N P T K G R V K K K E K T P L R D(735) of human RIP140.

Reactivity Notes

Cross-reactivity with Non-human primate.

Specificity

Detects a band at approximately 140 kDa.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

140 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RIP140 Antibody

Western Blot: RIP140 Antibody [NB110-5122]

Western Blot: RIP140 Antibody [NB110-5122] - Analysis of recombinant human.

Applications for RIP140 Antibody

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Western Blot

2 ug/ml

Application Notes

ICC/IF usage reported in scientific literature (PMID: 7641693).

Reviewed Applications

Read 1 review rated 3 using NB110-5122 in the following applications:

Western Blot (1 Review)

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RIP140

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Receptor Interacting Protein 140 (RIP 140) has been shown to enhance estrogen receptor transcriptional activity through the AF2 activation domain in an agonist dependent manner and has also been implicated to be involved in other steroid receptor pathways, including the retinoid pathway. RIP 140 has recently been shown to interact with peroxisome proliferator-activated receptor-alpha (PPAR alpha) and has been proposed to competitively inhibit PPAR alpha interaction with Steroid Receptor Coactivator-1 (SRC-1).

Alternate Names

10RIP140Receptor-interacting protein 140, FLJ77253, nuclear receptor interacting protein 1, nuclear receptor-interacting protein 1, receptor interacting protein 140

Entrez Gene IDs

8204 (Human)

Gene Symbol

NRIP1

Additional RIP140 Products

Product Documents for RIP140 Antibody

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Certificate of Analysis

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Product Specific Notices for RIP140 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for RIP140 Antibody (1)

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Name: Anonymous

Application: Western Blot

Sample Tested: 293T cell lysate

Species: Human

Verified Customer | Posted 09/05/2014

RIP 140 western in 293T cells

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