RJR 2403 oxalate

Catalog # Availability Size / Price Qty
RJR 2403 oxalate | CAS No. 220662-95-3 | Nicotinic (a4b2) Receptor Agonists
1 Image
Description: Selective α4β2 nAChR agonist
Alternative Names: Metanicotine, TC-2403

Chemical Name: (E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate

Purity: ≥99%

Product Details
Citations (6)
Supplemental Products

Biological Activity

RJR 2403 oxalate is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Active in vivo.

Technical Data

Soluble to 100 mM in water
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Experiment

Background References

  1. RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization.
    Bencherif et al.
    J.Pharmacol.Exp.Ther., 1996;279:1413
  2. Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist.
    Damaj et al.
    J.Pharmacol.Exp.Ther., 1999;291:390
  3. RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization.
    Lippiello et al.
    J.Pharmacol.Exp.Ther., 1996;279:1422

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for RJR 2403 oxalate


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for RJR 2403 oxalate

There are currently no reviews for this product. Be the first to review RJR 2403 oxalate and earn rewards!

Have you used RJR 2403 oxalate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.