RJR 2403 oxalate

  ( 6 citations )    
Product Datasheet
Catalog Number:1053
Alternate Names:Metanicotine, TC-2403
Chemical Name:(E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate
Product Details
Citations (6)
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Reviews
Biological Activity
A neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Active in vivo.
Technical Data
  • M.Wt:
    252.27
  • Formula:
    C10H14N2.C2H2O4
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    220662-95-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for RJR 2403 oxalate include:

6 Citations: Showing 1 - 6
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  1. Nicotinic acetylcholine receptors containing the α7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle.
    Authors: Kiss Et al.
    PLoS One  2014;9:e109538
  2. Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.
    Authors: Zhong Et al.
    Dev Neurobiol  2013;8:e82719
  3. α4β2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion.
    Authors: Scholze Et al.
    Cardiovasc Res  2011;71:390
  4. Chronic cerebral ischaemia forms new cholinergic mechanisms of learning and memory.
    Authors: Zakharova Et al.
    Int J Alzheimers Dis  2011;2010:954589
  5. Specific subtypes of nicotinic cholinergic receptors involved in sympathetic and parasympathetic cardiovascular responses.
    Authors: Li Et al.
    Neurosci Lett  2009;462:20
  6. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides.
    Authors: Liu Et al.
    J Neurosci  2009;29:918

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