9 results for "Nicotinic (a4b2) Receptor Agonists" in Products

Nicotinic (a4b2) Receptor Agonists

Prototypical nAChR agonist

Chemical Name: (S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine (L-(+))-ditartrate salt
Purity: ≥99%
Prototypical nAChR agonist
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Selective α4β2 nAChR partial agonist; orally active

Chemical Name: 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate
Purity: ≥99%
Selective α4β2 nAChR partial agonist; orally active
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Selective α4β2 nAChR agonist

Alternate Names: Metanicotine,TC-2403
Chemical Name: (E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate
Purity: ≥99%
Selective α4β2 nAChR agonist
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Potent α4β4, α4β2 and α7 nAChR agonist

Chemical Name: (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
Purity: ≥98%
Potent α4β4, α4β2 and α7 nAChR agonist
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High affinity and selective α4β2 nAChR partial agonist

Chemical Name: 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride
Purity: ≥98%
High affinity and selective α4β2 nAChR partial agonist
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Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs

Chemical Name: 3-(2-Chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole hydrochloride
Purity: ≥98%
Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs
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Selective α4β2 nAChR agonist

Alternate Names: Tebanicline
Chemical Name: (R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride
Purity: ≥98%
Selective α4β2 nAChR agonist
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Selective α4β2 nAChR partial agonist

Chemical Name: 4-(5-ethoxy-3-pyridinyl)-N-methyl-(3E)-3-buten-1-amine difumarate
Purity: ≥98%
Selective α4β2 nAChR partial agonist
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Highly potent PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

Chemical Name: 1-Methyl-7,8,9,10-tetrahydro-1H-6,10-methanoazepino[4,5-g]quinoxalin-2(6H)-one hydrochloride
Purity: ≥98%
Highly potent PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
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