Rp-8-Br-PET-cGMPS

Tocris Bioscience | Catalog # 3028

Protein kinase G inhibitor
Tocris Bioscience

Key Product Details

Description

Protein kinase G inhibitor
View all Protein Kinase G Inhibitors »

Product Description

Rp-8-Br-PET-cGMPS is a competitive, reversible cGMP-dependent protein kinase (PKG) inhibitor; cGMP analog.

This product is sold in units of 560μg, equivalent to 1μmol.

Product Specifications for Rp-8-Br-PET-cGMPS

Molecular Weight

562.27

Formula

C18H14BrN5NaO6PS

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-Bromo-3,4-dihydro-3-[3,5-O-[(R)-mercaptophosphinylidene]-β-D-ribofuranosyl]-6-phenyl-9H-Imidazo[1,2-a]purin-9-one sodium salt

CAS Number

185246-32-6

PubChem ID

23695925

InChI Key

PNUXBFRWMZKKAJ-IPZAVTHYSA-M

SMILES

[H][C@@]([C@@](O[C@@H](N3C(Br)=NC5=C3NC4=NC(C6=CC=CC=C6)=CN4C5=O)[C@@H]2O)([H])CO1)2O[P@@]1(S[Na])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 11.25 20
DMSO 22.49 40

Preparing Stock Solutions for Rp-8-Br-PET-cGMPS

The following data is based on the product molecular weight 562.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.4 mM 4.45 mL 22.23 mL 44.46 mL
2 mM 0.89 mL 4.45 mL 8.89 mL
4 mM 0.44 mL 2.22 mL 4.45 mL
20 mM 0.09 mL 0.44 mL 0.89 mL

Calculators

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Product Documents for Rp-8-Br-PET-cGMPS

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rp-8-Br-PET-cGMPS

For research use only

Citations for Rp-8-Br-PET-cGMPS

Customer Reviews for Rp-8-Br-PET-cGMPS (1)

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  • PKG inhibitor in vitro
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Neuron
    Verified Customer | Posted 08/11/2018
    Excellent PKG inhibitor
    Used in cultured neurons at 10 uM

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