Rucaparib camsylate

Tocris Bioscience | Catalog # 6230

PARP inhibitor
Tocris Bioscience

Key Product Details

Description

PARP inhibitor

Alternative Names

CO-338
View all Poly(ADP-ribose) Polymerase Inhibitors »

Product Description

Rucaparib camsylate is a PARP inhibitor. Chemosensitizes colorectal cancer cells to Temozolomide (Cat. No. 2706) and Topotecan (Cat. No. 4562) in vitro and in vivo.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for Rucaparib camsylate

Molecular Weight

555.66

Formula

C19H18FN3O.C10H16O4S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid

CAS Number

1859053-21-6

PubChem ID

53356947

InChI Key

INBJJAFXHQQSRW-FHIDHQGESA-N

SMILES

CNCC1=CC=C(C2=C3CCNC(C4=C3C(N2)=CC(F)=C4)=O)C=C1.O=S(C[C@@]5(C6(C)C)CC[C@@H]6CC5=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 55.57 100

Preparing Stock Solutions for Rucaparib camsylate

The following data is based on the product molecular weight 555.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.80 mL 9.00 mL 18.00 mL
5 mM 0.36 mL 1.80 mL 3.60 mL
10 mM 0.18 mL 0.90 mL 1.80 mL
50 mM 0.04 mL 0.18 mL 0.36 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Rucaparib camsylate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rucaparib camsylate

For research use only

Related Research Areas

Apoptosis

Citations for Rucaparib camsylate

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