Partial agonist of α
7 nAChR. Improves mnemonic function in aged mice for the treatment of aging-related memory disturbances. Displays more efficient memory-enhancing effects than memantine
(Cat. No. 0773) in Alzheimer's disease mouse models.
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The partial α7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus.
Lagostena et al.
Comparative effects of the α7 nicotinic partial agonist, S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice.
Marighetto et al.
Improvement of contextual memory by S 24795 in aged mice: comparison with memantine.
Beracochea et al.