(S)-4-Carboxyphenylglycine

Tocris Bioscience | Catalog # 0323

Competitive group I mGlu antagonist; also weak group II agonist
Tocris Bioscience

Key Product Details

Description

Competitive group I mGlu antagonist; also weak group II agonist

Alternative Names

(S)-4CPG
View all Group I mGluR Antagonists »

Product Description

(S)-4-Carboxyphenylglycine is a competitive group I metabotropic glutamate receptor antagonist, with selectivity for mGlu1a/1a over mGlu5a/5b.

Product Specifications for (S)-4-Carboxyphenylglycine

Molecular Weight

195.17

Formula

C9H9NO4

Storage

Store at RT

Purity

≥98% (HPLC)

CAS Number

134052-73-6

PubChem ID

5311459

InChI Key

VTMJKPGFERYGJF-ZETCQYMHSA-N

SMILES

[H][C@@](N)(C(O)=O)C1=CC=C(C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. NaOH 19.52 100 with gentle warming

Preparing Stock Solutions for (S)-4-Carboxyphenylglycine

The following data is based on the product molecular weight 195.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.12 mL 25.62 mL 51.24 mL
5 mM 1.02 mL 5.12 mL 10.25 mL
10 mM 0.51 mL 2.56 mL 5.12 mL
50 mM 0.10 mL 0.51 mL 1.02 mL

Calculators

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Product Documents for (S)-4-Carboxyphenylglycine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (S)-4-Carboxyphenylglycine

For research use only

Citations for (S)-4-Carboxyphenylglycine

Customer Reviews for (S)-4-Carboxyphenylglycine (1)

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  • (S)-4-carboxyphenylglycine (CPG)(0.2 uM)
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: LP-1 cell line
    Verified Customer | Posted 12/11/2019
    Treatment with (S)-4-carboxyphenylglycine (CPG) ensitizes LP-1/Cfz cells. Cells were treated with the indicated concentrations of carfilzomib for 72 hours in the absence or presence of CPG (0.2 uM)
    (S)-4-Carboxyphenylglycine 0323

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