(S)-4-Carboxyphenylglycine

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(S)-4-Carboxyphenylglycine | CAS No. 134052-73-6 | Group I mGluR Antagonists
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Description: Competitive group I mGlu antagonist; also weak group II agonist
Alternative Names: (S)-4CPG

Purity: ≥99%

Product Details
Citations (7)
Reviews (1)

Biological Activity

Competitive group I metabotropic glutamate receptor antagonist, with selectivity for mGlu1a/1a over mGlu5a/5b.

Racemate and R-enantiomer also available.

Technical Data

M.Wt:
195.17
Formula:
C9H9NO4
Solubility:
Soluble to 100 mM in 1eq. NaOH with gentle warming
Purity:
≥99%
Storage:
Store at RT
CAS No:
134052-73-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for (S)-4-Carboxyphenylglycine

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(S)-4-carboxyphenylglycine (CPG)(0.2 uM)
By Anonymous on 12/11/2019
Application: Species: Human

Treatment with (S)-4-carboxyphenylglycine (CPG) ensitizes LP-1/Cfz cells. Cellswere treated with the indicated concentrations of carfilzomib for 72 hours in the absence or presence of CPG (0.2 uM)

PMID: 27626179

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