(S)-(+)-Dimethindene maleate

Catalog # Availability Size / Price Qty
1425/10
1425/50

15% Off Limited-time Savings on Your Reagents, Assays, and Kits
Now through September 27th, you can save 15% on Bio-Techne reagents, assays, and kits (including Novus, Tocris, and R&D Systems). Use promotion code SAVE15 at checkout on orders over $1,000. See terms and conditions for offer details.

(S)-(+)-Dimethindene maleate | CAS No. 136152-65-3 | mAChR M2 Antagonists
1 Image
Description: Selective M2 antagonist

Chemical Name: N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate

Purity: ≥99%

Product Details
Citations (6)
Supplemental Products
Reviews

Biological Activity

(S)-(+)-Dimethindene maleate is an enantiomer that is a subtype-selective M2 muscarinic receptor antagonist (pKi values are 7.08, 7.78, 6.70 and 7.00 for M1, M2, M3 and M4 receptors respectively). Also H1 histamine receptor antagonist (pKi = 7.48). Allows formation of extended pluripotent stem (EPS) cells in combination with CHIR 99021 (Cat.No. 4423), minocycline hydrochloride (Cat.No. 3268) and human leukemia inhibitory factor.

For more information about how Dimethindene maleate may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail).

Technical Data

M.Wt:
408.5
Formula:
C20H24N2.C4H4O4
Solubility:
Soluble to 100 mM in water with gentle warming
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
136152-65-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for (S)-(+)-Dimethindene maleate

The citations listed below are publications that use Tocris products. Selected citations for (S)-(+)-Dimethindene maleate include:

6 Citations: Showing 1 - 6

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for (S)-(+)-Dimethindene maleate

There are currently no reviews for this product. Be the first to review (S)-(+)-Dimethindene maleate and earn rewards!

Have you used (S)-(+)-Dimethindene maleate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.