A selective h5-HT1B
antagonist with approximately 25-fold selectivity over h5-HT1D
and little or no affinity for a range of other receptor types.
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All Tocris products are intended for laboratory research use only.
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SB-216641 and BRL-15572 - compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors.
Price et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1997;356:312
Effects of selective h5-HT1B (SB-216641) and 5-HT1D (BRL-15572) receptor ligands on guinea pig and human 5-HT auto- and heteroreceptors.
Schlicker et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1997;356:321
Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.
Hagan et al.
The citations listed below are publications that use Tocris products. Selected citations for SB 216641 hydrochloride include:
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