SC 26196

  ( 1 citations )    
Product Datasheet
Catalog Number:4189
Chemical Name:α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
Product Details
Citations (1)
Reviews
Biological Activity
Selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro). Displays selectivity over Δ5 and Δ9 desaturases (IC50 values are >200 μM in vitro). Exhibits anti-inflammatory properties in a mouse edema model. Eliminates CSCs from ovarian cancer cell lines and inhibits sphere formation in vitro.
Technical Data
  • M.Wt:
    423.55
  • Formula:
    C27H29N5
  • Solubility:
    Soluble to 25 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    218136-59-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SC 26196 include:

1 Citations: Showing 1 - 1

  1. Correlating chemical sensitivity and basal gene expression reveals mechanism of action.
    Authors: Rees Et al.
    PLoS One  2016;12:109

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