SCH 202676 hydrobromide
Chemical Name: N-(2,3-Diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)methanamine hydrobromide
Biological ActivitySCH 202676 hydrobromide is a sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors. Inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors (IC50 values are 0.1-1.8 μM).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
SCH-202676: an allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors.
Fawzi et al.
Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors.
Gao et al.
Life Sci., 2004;74:3173
The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.
Lewandowicz et al.
Citation for SCH 202676 hydrobromide
The citations listed below are publications that use Tocris products. Selected citations for SCH 202676 hydrobromide include:
1 Citation: Showing 1 - 1
Both Type I and Type II Interferons Can Activate Antitumor M1 Macrophages When Combined With TLR Stimulation.
Authors: M?ller Et al.
Front Immunol 2018;9:2520
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