Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG Clone # RB57630
View all Scn1a Primary Antibodies »

Product Specifications

Immunogen

This SCN1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 481-515 amino acids from the Central region of human SCN1A.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Scn1a Antibody (RB57630)

Scn1a Antibody (RB57630)

Flow Cytometry:Scn1a Antibody (RB57630)[NBP3-52190]-

Anti-SCN1A Antibody (Center) at 1:2000 dilution + U-87 MG whole cell lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 229 kDaBlocking/Dilution buffer: 5% NFDM/TBST.
Scn1a Antibody (RB57630)

Western Blot:Scn1a Antibody (RB57630)[NBP3-52190]-

Anti-SCN1A Antibody (Center) at 1:2000 dilution + U-87 MG whole cell lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 229 kDaBlocking/Dilution buffer: 5% NFDM/TBST.

Applications for Scn1a Antibody (RB57630)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Scn1a

Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript. [provided by RefSeq, Oct 2015]

Alternate Names

brain I alpha subunit, DEE6, DEE6A, DEE6B, DRVT, EIEE6, FEB3, FEB3A, FHM3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI, sodium channel, voltage-gated, type I, alpha polypeptide, sodium channel, voltage-gated, type I, alpha subunit

Gene Symbol

SCN1A

Additional Scn1a Products

Product Documents for Scn1a Antibody (RB57630)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Scn1a Antibody (RB57630)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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