SECISBP2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-45407

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all SECISBP2 Primary Antibodies »

Product Specifications

Immunogen

SECIS binding protein 2. (Uniprot# Q96T21)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SECISBP2 Antibody - BSA Free

SECISBP2 Antibody - BSA Free

Western Blot: SECISBP2 Antibody - BSA Free [NBP3-45407] -

Western Blot: SECISBP2 Antibody - BSA Free [NBP3-45407] - HeLa cells were subjected to SDS PAGE followed by western blot with FNab07595(SECISBP2 antibody) at dilution of 1:1000
SECISBP2 Antibody - BSA Free

Immunohistochemistry: SECISBP2 Antibody - BSA Free [NBP3-45407] -

Immunohistochemistry: SECISBP2 Antibody - BSA Free [NBP3-45407] - Immunohistochemistry of paraffin-embedded human liver injury using (SECISBP2 antibody) at dilution of 1:100

Applications for SECISBP2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:100

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SECISBP2

SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.

Alternate Names

DKFZp686C09169, SBP2SECIS-binding protein 2, SECIS binding protein 2, selenocysteine insertion sequence binding protein 2, selenocysteine insertion sequence-binding protein 2

Gene Symbol

SECISBP2

Additional SECISBP2 Products

Product Documents for SECISBP2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SECISBP2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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