Serpin B5/Maspin Antibody [Biotin]

Novus Biologicals | Catalog # NB110-97377B

Novus Biologicals

Key Product Details

Species Reactivity

Human

Applications

Western Blot, ICC/IF (Negative), Knockdown Validated

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG
View all Serpin B5/Maspin Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide made to an internal portion of human MASPIN (within residues 100-200). [Swiss-Prot# P36952]

Localization

Secreted, extracellular space.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Serpin B5/Maspin Antibody [Biotin]

Application
Recommended Usage

ICC/IF (Negative)

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Serpin B5/Maspin

Maspin is an extracellular matrix tumor supressor that blocks the growth, invasion, and metastatic properties of mammary and prostate tumors. Structurally Maspin is a serine protease inhibitor (Serpin), but it does not undergo the stressed to relaxed conformational transition characteristic of active serpins and exhibits no serine protease inhibitory activity. Maspin is also expressed by the corneal epithelium and regulates migration and adhesion of corneal stromal fibroblasts and myofibroblasts during corneal wound healing.

Alternate Names

Maspin, PI5

Gene Symbol

SERPINB5

Additional Serpin B5/Maspin Products

Product Documents for Serpin B5/Maspin Antibody [Biotin]

Certificate of Analysis

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Product Specific Notices for Serpin B5/Maspin Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Serine Proteases and Regulators

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