SHANK1 Antibody (M369)

Novus Biologicals | Catalog # NBP3-23391

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # M369
View all SHANK1 Primary Antibodies »

Product Specifications

Immunogen

Clone M369 was generated from a sequence corresponding to amino acids in the C-terminal region of rat SHANK1. This sequence has high homology to human and mouse SHANK1. [UniProt# Q9WV48]

Specificity

This antibody detects a 225 kDa protein corresponding to the molecular mass of Shank1 on SDS-PAGE immunoblots of adult mouse brain.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

225 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Stable for at least 1 year at -20°C.

Scientific Data Images for SHANK1 Antibody (M369)

SHANK1 Antibody (M369)

Western Blot: SHANK1 Antibody (M369) [NBP3-23391] -

Western Blot: SHANK1 Antibody (M369) [NBP3-23391] - Western blot of mouse brain lysate. The blot was probed with mouse monoclonal anti-SHANK1 (C-terminal region) antibody at 1:250 (lane 1), 1:500 (lane 2), or 1:1000 (lane 3).

Applications for SHANK1 Antibody (M369)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 1 mg/ml BSA and 50% glycerol

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: SHANK1

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Alternate Names

SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, Shank1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIPSPANK-1, synamon

Gene Symbol

SHANK1

Additional SHANK1 Products

Product Documents for SHANK1 Antibody (M369)

Certificate of Analysis

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Product Specific Notices for SHANK1 Antibody (M369)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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