SIGIRR Antibody - BSA Free

Novus Biologicals | Catalog # NB100-56890

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids 334-358 of human SIGIRIR.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SIGIRR Antibody - BSA Free

Western Blot: SIGIRR Antibody [NB100-56890]

Western Blot: SIGIRR Antibody [NB100-56890]

Western Blot: SIGIRR Antibody [NB100-56890] - Analysis of human SIGIRR in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using this antibody at 0.5 ug/ml.

Applications for SIGIRR Antibody - BSA Free

Application
Recommended Usage

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SIGIRR

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). TIR8, also know as single Ig IL-1 receptor, is a member of the IL-1/TLR superfamily (2). TIR8 acts as intracellular decoy to inhibit NF-kappaB activation by members of the IL-1/TLR family (3, 4).

Long Name

Single lg IL-1 Related Protein

Alternate Names

IL-1R8, TIR8

Entrez Gene IDs

59307 (Human); 24058 (Mouse)

Gene Symbol

SIGIRR

UniProt

Additional SIGIRR Products

Product Documents for SIGIRR Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SIGIRR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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Associated Pathways

IL-1 Family Signaling Pathways IL-1 Family Signaling Pathway Thumbnail