Key Product Details

Species Reactivity

Human

Applications

Western Blot, Blockade of Receptor-ligand Interaction, Flow Cytometry, CyTOF-ready

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Siglec-11
Asn17-His543 (Glu84Ala, Lys145Gln)
Accession # Q96RL6

Specificity

Detects human Siglec-11 in direct ELISAs and Western blots. In direct ELISA and Western blots, approximately 20% cross-reactivity with recombinant human (rh) Siglec-10 is observed and less than 5% cross-reactivity with rhSiglec-2, -3, -5, -6, -7, -9 and recombinant mouse Siglec-F is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Siglec-11 Antibody [DyLight 405]

Application
Recommended Usage

Blockade of Receptor-ligand Interaction

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

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Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Siglec-11

SIGLECs are a family of cell surface lectins defined by shared structural motifs in the first 2 immunoglobulin(Ig)-like domains and by their ability to recognize sialic acids via the first Ig V set domain.(supplied by OMIM)

Long Name

Sialic Acid Binding Ig-like Lectin 11

Alternate Names

Siglec11

Gene Symbol

SIGLEC11

Additional Siglec-11 Products

Product Documents for Siglec-11 Antibody [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Siglec-11 Antibody [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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