SIGNR1/CD209b Antibody (ER-TR9)

Novus Biologicals | Catalog # NBP1-42424

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Flow Cytometry, Functional

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgM Clone # ER-TR9
View all SIGNR1/CD209b Primary Antibodies »

Product Specifications

Immunogen

The antibody reacts with the SIGN-R1 antigen.

Specificity

Does not react with macrophages in other regions of the spleen, such as CD169+ marginal metallophils and F4/80+ red pulp macrophages.

Clonality

Monoclonal

Host

Rat

Isotype

IgM

Applications for SIGNR1/CD209b Antibody (ER-TR9)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500
Application Notes
Uptake of FITC-labeled dextran by macrophages can be blocked both in vivo and in vitro by the monoclonal antibody ER-TR9. Therefore, the monoclonal antibody ER-TR9 can be used to study the uptake of polysaccharides by macrophages.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Sterile culture medium

Preservative

0.02% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SIGNR1/CD209b

Mouse SIGNR1 is a type II transmembrane protein that is a homolog of human DCSIGN (R). It is a C-type lectin expressed by marginal zone macrophages and by medullary and subcapsular macrophages in lymph nodes. SIGN R1 binds and mediates the uptake of dextran via mannose and fucose binding sites.

Long Name

SIGN-related 1

Alternate Names

CD209b

Gene Symbol

Cd209a

Additional SIGNR1/CD209b Products

Product Documents for SIGNR1/CD209b Antibody (ER-TR9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SIGNR1/CD209b Antibody (ER-TR9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SIGNR1/CD209b Antibody (ER-TR9)

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for SIGNR1/CD209b Antibody (ER-TR9)

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  • Q: For the following product, could you let us know the buffer composition? #NBP1-42424 SIGN-R1 Antibody (ER-TR9) Preservative: No Preservative

    A: The SIGN-R1 antibody with catalogue number NBP1-42424 is supplied as sterile culture media, with no added preservatives.

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