SLC7A5/LAT1 Antibody - BSA Free

Novus Biologicals | Catalog # NB110-39037

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all SLC7A5/LAT1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic 15 amino acid peptide from internal region of human SLC7A5/LAT1.

Epitope

Internal domain of human.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Gorilla (93%), Mouse (80%), Rat (80%), Canine (80%), Bat (80%).

Localization

Integral membrane protein

Specificity

This is specific to the human SLC7A5/LAT1 protein. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for SLC7A5/LAT1 Antibody - BSA Free

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody - BSA Free [NB110-39037]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody - BSA Free [NB110-39037]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody - BSA Free [NB110-39037] - Human testis

Applications for SLC7A5/LAT1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: SLC7A5/LAT1

Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.

Long Name

Solute Carrier Family 7 Member 5

Alternate Names

4F2LC, CD98lc, E16, LAT1, MPE16, TA1

Gene Symbol

SLC7A5

Additional SLC7A5/LAT1 Products

Product Documents for SLC7A5/LAT1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SLC7A5/LAT1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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