SMER 28

Catalog # Availability Size / Price Qty
4297/10
4297/50
Autophagy-related Compounds Small Molecule
1 Image
Description: Positive regulator of autophagy

Chemical Name: 6-Bromo-N-2-propenyl-4-quinazolinamine

Purity: ≥99%

Product Details
Citations (3)
Reviews

Biological Activity

Positive regulator of autophagy in a mechanism independent from the mTOR pathway. Increases autophagosome synthesis and enhances clearance of model autophagy substrates such as mutant huntingtin and A53T α-synuclein, associated with Huntington's and Parkinson's diseases, respectively. Promotes reprogramming of fibroblasts to neural stem-like cells in combination with other chemical reagents.

Technical Data

M.Wt:
264.12
Formula:
C11H10BrN3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
307538-42-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reconstitution Calculator

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Citations for SMER 28

The citations listed below are publications that use Tocris products. Selected citations for SMER 28 include:

3 Citations: Showing 1 - 3

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