Selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30
) in vitro
and in vivo
. Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin
(Cat. No. 1292).
Soluble to 75 mM in DMSO
Store at +4°C
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Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor.
Aghajanyy et al.