Somatostatin Antibody (YC7) - BSA Free

Novus Biologicals | Catalog # NB100-64650

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Cited:

Immunohistochemistry Free-Floating, IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2B Clone # YC7

Format

BSA Free
View all Somatostatin Primary Antibodies »

Product Specifications

Immunogen

Somatostatin conjugated to thyroglobulin

Reactivity Notes

Predicted cross-reactivities: Porcine, Mouse, Guinea Pig, Rat, Zebrafish

Localization

Secreted

Specificity

NB100-64650 is specific for somatostatin. A hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product.This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially cross reacts with somatostatin fragments. The epitope recognized by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for Somatostatin Antibody (YC7) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Formulation, Preparation, and Storage

Purification

Tissue culture supernatant

Formulation

Tissue culture supernatant

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Somatostatin

The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas.

Alternate Names

SMST, SOM, SRIF, SST

Entrez Gene IDs

6750 (Human); 6750 (Human)

Gene Symbol

SST

UniProt

P61278

Additional Somatostatin Products

Product Documents for Somatostatin Antibody (YC7) - BSA Free

Certificate of Analysis

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Product Specific Notices for Somatostatin Antibody (YC7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Citations for Somatostatin Antibody (YC7) - BSA Free

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Protocols

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