SRRM1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-13381

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Simple Western

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all SRRM1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: RQRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRRM1 Antibody - BSA Free

Simple Western: SRRM1 Antibody [NBP2-13381]

Simple Western: SRRM1 Antibody [NBP2-13381]

Simple Western: SRRM1 Antibody [NBP2-13381] - Simple Western lane view shows a specific band for SRRM1 in 0.2 mg/ml of HEK 293T lysate(s). This experiment was performed under reducing conditions using the 12-230 kDa separation system.
Simple Western: SRRM1 Antibody [NBP2-13381]

Simple Western: SRRM1 Antibody [NBP2-13381]

Simple Western: SRRM1 Antibody [NBP2-13381] - Electropherogram image of the corresponding Simple Western lane view. SRRM1 antibody was used at 1:50 dilution on HEK 293T lysate(s) respectively.
SRRM1 Antibody - BSA Free

SRRM1 Antibody [NBP2-13381] -

Analysis in human cell line NB4.

Applications for SRRM1 Antibody - BSA Free

Application
Recommended Usage

Simple Western

1:50

Western Blot

0.04-0.4 ug/ml
Application Notes

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point.
See Simple Western Antibody Database for Simple Western validation: Tested in HEK 293T lysate, separated by Size, antibody dilution of 1:50, apparent MW was 203 kDa.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SRRM1

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates

Alternate Names

MGC39488, POP101, Ser/Arg-related nuclear matrix protein, serine/arginine repetitive matrix 1, serine/arginine repetitive matrix protein 1, SRm160, SRM160160-KD, SR-related nuclear matrix protein of 160 kDa

Gene Symbol

SRRM1

Additional SRRM1 Products

Product Documents for SRRM1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SRRM1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SRRM1 Antibody - BSA Free

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