STARD3 Antibody

Novus Biologicals | Catalog # NB300-599

Novus Biologicals
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Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all STARD3 Primary Antibodies »

Product Specifications

Immunogen

Recombinant MLN64 protein.

Specificity

MLN 64

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for STARD3 Antibody

Western Blot: STARD3 Antibody [NB300-599]

Western Blot: STARD3 Antibody [NB300-599]

Western Blot: STARD3 Antibody [NB300-599] - Analysis of MLN64 on rat adrenal gland extract.

Applications for STARD3 Antibody

Application
Recommended Usage

Western Blot

1 ug/ml
Application Notes
WB: Detects an approx. 53 kDa protein representing MLN 64 from rat adrenal gland tissue extracts. Also detects an approx. 25 kDa protein from rat adrenal gland which may correspond to degradation product.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: STARD3

The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN 64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN 64 are deleted, the resulting N-218 MLN 64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN 64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN 64 is similar to the organization of StAR. However, as MLN 64 never enters the mitochondria, the protease-resistant domain of MLN 64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.

Alternate Names

CAB1, es64, Metastatic lymph node gene 64 protein, metastatic lymph node protein 64, MLN 64, MLN64FLJ41370, Protein CAB1, StARD3, StAR-related lipid transfer (START) domain containing 3, stAR-related lipid transfer protein 3, START domain containing 3, START domain-containing protein 3, steroidogenic acute regulatory protein related

Entrez Gene IDs

291182 (Rat)

Gene Symbol

STARD3

Additional STARD3 Products

Product Documents for STARD3 Antibody

Certificate of Analysis

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Product Specific Notices for STARD3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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