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Rosiglitazone

  ( 2 citations )    
Product Datasheet
Catalog Number:5325
Alternate Names:BRL 49653
Chemical Name:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Potent and selective PPARγ agonist (EC50 = 60 nM); exhibits no activity at PPARα and PPARβ. Promotes differentiation of pluripotent C3H10T1/2 stem cells into adipocytes. Exhibits antihyperglycemic activity in diabetic ob/ob mouse model. Antidiabetic agent.
Technical Data
  • M.Wt:
    357.43
  • Formula:
    C18H19N3O3S
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    122320-73-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Rosiglitazone include:

2 Citations: Showing 1 - 2
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  1. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.
    Authors: Matsa Et al.
    Cell Stem Cell.  2016;19:311
  2. Studies of the pharmacology of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol, a synthetic anti-inflammatory androstene.
    Authors: Ahlem Et al.
    Int J Clin Exp Med  2011;4:119

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