Rosiglitazone

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5325/10
5325/50
Rosiglitazone | CAS No. 122320-73-4 | PPAR gamma Receptor Agonists
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Description: Potent and selective PPARγ agonist; antidiabetic agent
Alternative Names: BRL 49653

Chemical Name: 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

Purity: ≥98%

Product Details
Citations (7)
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Biological Activity

Rosiglitazone is a potent and selective PPARγ agonist (EC50 = 60 nM); exhibits no activity at PPARα and PPARβ. Promotes differentiation of pluripotent C3H10T1/2 stem cells into adipocytes. Also promotes differentiation of urothelial organoids in combination with Erlotinib (Cat. No. 7194). Exhibits antihyperglycemic activity in diabetic ob/ob mouse model. Antidiabetic agent.

Technical Data

M.Wt:
357.43
Formula:
C18H19N3O3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
122320-73-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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