Rosiglitazone

  ( 2 citations )    
Product Datasheet
Catalog Number:5325
Alternate Names:BRL 49653
Chemical Name:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Product Details
Citations (2)
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Reviews
Biological Activity
Potent and selective PPARγ agonist (EC50 = 60 nM); exhibits no activity at PPARα and PPARβ. Promotes differentiation of pluripotent C3H10T1/2 stem cells into adipocytes. Exhibits antihyperglycemic activity in diabetic ob/ob mouse model. Antidiabetic agent.
Technical Data
  • M.Wt:
    357.43
  • Formula:
    C18H19N3O3S
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    122320-73-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Rosiglitazone include:

2 Citations: Showing 1 - 2
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  1. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.
    Authors: Matsa Et al.
    Cell Stem Cell.  2016;19:311
  2. Studies of the pharmacology of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol, a synthetic anti-inflammatory androstene.
    Authors: Ahlem Et al.
    Int J Clin Exp Med  2011;4:119

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