Tamoxifen citrate

Tocris Bioscience | Catalog # 0999

Estrogen receptor partial agonist/antagonist
Tocris Bioscience

Key Product Details

Description

Estrogen receptor partial agonist/antagonist
View all Estrogen and Related Receptor Modulators »

Product Description

Tamoxifen citrate is an estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo. Also high affinity agonist at the membrane estrogen receptor GPER. Tamoxifen (Cat. No. 6432) is also available.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications for Tamoxifen citrate

Molecular Weight

563.65

Formula

C26H29NO.C6H8O7

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate

CAS Number

54965-24-1

PubChem ID

2733525

InChI Key

FQZYTYWMLGAPFJ-OQKDUQJOSA-N

SMILES

CC/C(C2=CC=CC=C2)=C(C3=CC=CC=C3)/C1=CC=C(OCCN(C)C)C=C1.O=C(O)CC(O)(C(O)=O)CC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 56.37 100
Ethanol 2.82 5 with gentle warming

Preparing Stock Solutions for Tamoxifen citrate

The following data is based on the product molecular weight 563.65.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.77 mL 8.87 mL 17.74 mL
5 mM 0.35 mL 1.77 mL 3.55 mL
10 mM 0.18 mL 0.89 mL 1.77 mL
50 mM 0.04 mL 0.18 mL 0.35 mL

Calculators

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Product Documents for Tamoxifen citrate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tamoxifen citrate

For research use only

⚠ WARNING: This product can expose you to chemicals including Tamoxifen citrate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for Tamoxifen citrate

Customer Reviews for Tamoxifen citrate (1)

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  • Blocks effects of estradoil
    Name: Ourlad Alzeus Tantengco
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Endocervical Epithelial Cells
    Verified Customer | Posted 01/30/2021
    Tamoxifen (1 ug/mL) was used to block the effects of estradiol in endocervical epithelial cells on intermediate filament (cytokeratin 18 and vimentin) expression.
    Tamoxifen citrate 0999

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