(Z)-4-Hydroxytamoxifen

Catalog # Availability Size / Price Qty
3412/10
3412/50
Cat.No. 3412 - (Z)-4-Hydroxytamoxifen | C26H29NO2 | CAS No. 68047-06-3
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Description: Metabolite of tamoxifen (Cat. No. 0999)
Alternative Names: 4-OH-TAM

Chemical Name: 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Estrogen receptor antagonist. Tamoxifen (Cat. No. 0999) metabolite; exhibits greater potency than the parent compound. Chemotherapeutic agent. Also activates intein-linked inactive Cas9, reducing off-target CRISPR-mediated gene editing; system has ~25-fold higher specificity than wtCas9.

Technical Data

M.Wt:
387.51
Formula:
C26H29NO2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
68047-06-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for (Z)-4-Hydroxytamoxifen

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