TC-MCH 7c

   
Product Datasheet
Catalog Number:4365
Chemical Name:4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone
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Biological Activity
Potent, selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist (IC50= 5.6 nM in hMCH1R-expressing CHO cells). Displays selectivity for MCH1R over MCH2R (IC50 = > 10 μM). Decreases body weight in a mouse model of diet-induced obesity. Brain penetrant; orally active.
Technical Data
  • M.Wt:
    408.47
  • Formula:
    C24H25FN2O3
  • Solubility:
    Soluble to 100 mM in 1eq. HCl and to 50 mM in DMSO
  • Purity:
    >97
  • Storage:
    Store at RT
  • CAS No:
    864756-35-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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