TC-MCH 7c

Catalog # Availability Size / Price Qty
4365/10
TC-MCH 7c | CAS No. 864756-35-4 | Melanin-concentrating Hormone Receptor Antagonists
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Description: Selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist

Chemical Name: 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone

Purity: ≥97%

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Biological Activity

Potent, selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist (IC50= 5.6 nM in hMCH1R-expressing CHO cells). Displays selectivity for MCH1R over MCH2R (IC50 = > 10 μM). Decreases body weight in a mouse model of diet-induced obesity. Brain penetrant; orally active.

Technical Data

M.Wt:
408.47
Formula:
C24H25FN2O3
Solubility:
Soluble to 100 mM in 1eq. HCl and to 50 mM in DMSO
Purity:
≥97%
Storage:
Store at RT
CAS No:
864756-35-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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