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3 results for "Melanin-concentrating Hormone Receptor Antagonists" in Products
Melanin-concentrating Hormone Receptor Antagonists
Melanin-concentrating hormone (MCH) is a neuropeptide that is expressed in the central and peripheral nervous systems and plays an important role in the control of feeding behaviors and energy metabolism. MCH acts on two GPCRs: MCH1 (GPR24) and MCH2 (GPR145).
MCH1 and MCH2 have very similar tissue distribution patterns and are expressed in many brain regions, particularly the ventromedial, dorsalmedial and arcuate nuclei of the hypothalamus and zona incerta. They are also found at lower levels ...
Potent and selective MCH1 antagonist
| Chemical Name: | N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamide hydrochloride |
| Purity: | ≥98% |
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MCH1 antagonist
| Chemical Name: | 6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one |
| Purity: | ≥95% |
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Selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist
| Chemical Name: | 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone |
| Purity: | ≥97% |
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