Chemical Name: (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone
Biological ActivityHighly selective EP4 agonist (EC50 = 2.5 nM; Ki = 1.2 nM). Displays no significant binding at other prostaglandin receptors at concentrations up to 14 μM.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery of a potent and selective agonist of the prostaglandin EP4 receptor.
Billot et al.
Citation for TCS 2510
The citations listed below are publications that use Tocris products. Selected citations for TCS 2510 include:
1 Citation: Showing 1 - 1
Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia.
Authors: Liu Et al.
Am J Physiol Renal Physiol 2012;303:F1425
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