TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-16952

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Dot Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free
View all TDP-43/TARDBP Primary Antibodies »

Product Specifications

Immunogen

A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDBP (NP_031401.1). SKSSGW

Modification

p Ser 409, p Ser 410

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Dot Blot: TDP-43/TARDBP [p Ser409, p Ser410] Antibody [NBP3-16952] - Dot-blot analysis of all sorts of peptides using TDP-43/TARDBP antibody (NBP3-16952) at 1:1000 dilution. Exposure time: 10s.
Dot Blot: TDP-43/TARDBP [p Ser409, p Ser410] Antibody [NBP3-16952] - Dot-blot analysis of all sorts of peptides using TDP-43/TARDBP antibody (NBP3-16952) at 1:1000 dilution. Exposure time: 1s.

Applications for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Application
Recommended Usage

Dot Blot

1:500 - 1:1000

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

Azide and BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TDP-43/TARDBP

TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

Long Name

TAR DNA-binding Protein 43

Alternate Names

ALS10, TARDBP, TDP43

Gene Symbol

TARDBP

Additional TDP-43/TARDBP Products

Product Documents for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Infectious Diseases

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