THDOC

Tocris Bioscience | Catalog # 6334

Positive modulator of GABAA receptors; endogenous neurosteroid
Tocris Bioscience

Key Product Details

Description

Positive modulator of GABAA receptors; endogenous neurosteroid
View all GABA-A Receptor Modulators »

Product Description

THDOC is a positive modulator of GABAA receptors. Potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro. Endogenous neurosteroid.

Product Specifications for THDOC

Molecular Weight

334.49

Formula

C21H34O3

Storage

Store at RT

Purity

≥95% (HPLC)

Chemical Name

(3α,5α)-3,21-Dihydroxypregnan-20-one

CAS Number

567-02-2

PubChem ID

91475

InChI Key

CYKYBWRSLLXBOW-SIDISFDHSA-N

SMILES

[H][C@@]12CC[C@@H]([C@]1(CC[C@]3([C@]2(CC[C@]4(C[C@@H](CC[C@]34C)O)[H])[H])[H])C)C(CO)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.45 100
Ethanol 33.45 100

Preparing Stock Solutions for THDOC

The following data is based on the product molecular weight 334.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.99 mL 14.95 mL 29.90 mL
5 mM 0.60 mL 2.99 mL 5.98 mL
10 mM 0.30 mL 1.49 mL 2.99 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.

Product Documents for THDOC

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for THDOC

For research use only

Related Research Areas

GABA Receptors

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