Key Product Details

Species Reactivity

Human

Applications

Western Blot, Block/Neutralize

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 2116C

Format

Azide and BSA Free
View all TL1A/TNFSF15 Primary Antibodies »

Product Specifications

Immunogen

Partial recombinant human TL1A protein (amino acids 72-251) [UniProt O95150]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

>90% by SDS PAGE

Scientific Data Images for TL1A/TNFSF15 Antibody (2116C) - Azide and BSA Free

Western Blot: TL1A/TNFSF15 Antibody (2116C)Azide and BSA Free [MAB7442]

Western Blot: TL1A/TNFSF15 Antibody (2116C)Azide and BSA Free [MAB7442]

Western Blot: TL1A/TNFSF15 Antibody (2116C) [MAB7442] - Analysis of human prostate, kidney, and lung tissue lysates with 1 ug/ml of hTL1A Monoclonal Antibody followed by HRP-conjugated Anti-Rabbit IgG Antibody. A specific band was detected for hTL1A at approximately 22 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Applications for TL1A/TNFSF15 Antibody (2116C) - Azide and BSA Free

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TL1A/TNFSF15

VEGI is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined

Long Name

TNF-like 1

Alternate Names

TNFSF15, VEGI

Gene Symbol

TNFSF15

Additional TL1A/TNFSF15 Products

Product Documents for TL1A/TNFSF15 Antibody (2116C) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TL1A/TNFSF15 Antibody (2116C) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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