CD28 homolog (CD28H), also called TMIG2 and IGPR-1, is a 55 kDa glycosylated transmembrane protein that is constitutively expressed on naive T and NK cells. The interaction of CD28H with B7-H7 induces effector and memory T cell proliferation and activation. CD28H also regulates epithelial cell morphology, focal adhesion contact formation, and cell migration as well as angiogenesis. It interacts with multiple cytoskeletal proteins including Actin, Paxillin, SPIN90, CACNB2, and BPAG1.
TMIGD2 Antibody (953743) [Biotin]
Novus Biologicals | Catalog # FAB83162B
Key Product Details
Species Reactivity
Human
Applications
Blockade of Receptor-ligand Interaction, Flow Cytometry, CyTOF-ready
Label
Biotin
Antibody Source
Recombinant Monoclonal Mouse IgG2A Clone # 953743
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Product Specifications
Immunogen
Human embryonic kidney cell line HEK-293-derived human TMIGD2/CD28H
Met1-Gly150
Accession # Q96BF3
Met1-Gly150
Accession # Q96BF3
Specificity
Detects human TMIGD2/CD28H in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for TMIGD2 Antibody (953743) [Biotin]
Application
Recommended Usage
Blockade of Receptor-ligand Interaction
Optimal dilutions of this antibody should be experimentally determined.
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Flow Cytometry Panel Builder
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Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.
Advanced Features
- Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
- Spillover Popups - Visualize the spectra of individual fluorochromes
- Antigen Density Selector - Match fluorochrome brightness with antigen density
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: TMIGD2/CD28H
Long Name
Transmembrane And Immunoglobulin Domain Containing 2
Alternate Names
CD28H, IGPR-1, IGPR1
Additional TMIGD2/CD28H Products
Product Documents for TMIGD2 Antibody (953743) [Biotin]
Product Specific Notices for TMIGD2 Antibody (953743) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- Protocol: Annexin V and PI Staining by Flow Cytometry
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- Troubleshooting Guide: Fluorokine Flow Cytometry Kits
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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