TNP-ATP triethylammonium salt

  ( 3 citations )    
Product Datasheet
Catalog Number:2464
Chemical Name:2',3'-O-(2,4,6-Trinitrophenyl)adenosine-5'-triphosphate tetra(triethylammonium) salt
Product Details
Citations (3)
Reviews
Biological Activity
High affinity, selective P2X receptor antagonist. Inhibits ATP-induced currents in cells expressing P2X1, P2X3 and heteromeric P2X2/3 receptors with IC50 values of 6, 0.9 and 7 nM respectively. Displays 1000-fold selectivity over P2X2, P2X4 and P2X7.
Technical Data
  • M.Wt:
    1123.04
  • Formula:
    C16H13N8O19P3.C24H64N4
  • Solubility:
    Soluble in water (supplied pre-dissolved at a concentration of 10mM)
  • Purity:
    >95
  • Storage:
    Desiccate at -20°C
  • CAS No:
    61368-63-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for TNP-ATP triethylammonium salt include:

3 Citations: Showing 1 - 3
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  1. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells.
    Authors: Ghalali Et al.
    J Biol Chem  2014;289:11601
  2. Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium.
    Authors: Shabir Et al.
    Naunyn Schmiedebergs Arch Pharmacol  2013;305:F396
  3. ATP release and autocrine signaling through P2X4 receptors regulate γδ T cell activation.
    Authors: Manohar Et al.
    J Leukoc Biol  2012;92:787

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