Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit

Catalog # Availability Size / Price Qty
PKGE001
SKGE001
KGE001
Control Products Available
Multi-species Total Nitric Oxide and Nitrate/Nitrite ELISA Standard Curve
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Product Details
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Citations (166)
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Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit Summary

Format
96-well strip plate
Assay Length
< 1 hour
Sample Type & Volume Required Per Well
Cell Culture Supernates (10 uL), Serum (25 uL), EDTA Plasma (25 uL), Heparin Plasma (25 uL), Citrate Plasma (25 uL), Urine (10 uL)
Sensitivity
0.78 umol/L
Assay Range
3.1 - 200 umol/L (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)
Specificity
Measures Total Nitric Oxide, Nitrite and Nitrate levels in various samples
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
Interference observed with other substances.

Product Summary

The Parameter Total Nitric Oxide kit has two assay options. Endogenous nitrite is measured in the first option. In the second option, nitrate is converted to nitrite using nitrate reductase and total nitrite is measured. To obtain the nitrate concentration, endogenous nitrite is subtracted from the total nitrite value.

Recovery

The recovery of the nitrate standard spiked to levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (Nitrite Assay) (n=10) 107 91-115
Plasma (Nitrate Assay) (n=25) 98 87-110
Plasma (Nitrite Assay) (n=20) 104 92-117
Serum (Nitrate Assay) (n=10) 95 89-101
Serum (Nitrite Assay) (n=10) 109 98-118
Urine (Nitrite Assay) (n=10) 101 87-112

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of the nitrate standard were serially diluted with the Reaction Diluent to produce samples with values within the dynamic range of the assay.
Multi-species Total Nitric Oxide and Nitrate/Nitrite ELISA Linearity

Scientific Data

Multi-species Total Nitric Oxide and Nitrate/Nitrite ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Assay Procedure

Nitrite Assay Procedure
Nitrate Reduction Assay Procedure


Refer to the product for complete assay procedure.

This assay procedure measures the concentration of endogenous nitrite present in the sample. Bring all reagents and samples to room temperature before use. It is recommended that all samples and standards be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Reaction Diluent (1X)
  4.   Add 50 µL of Reaction Diluent (1X) to the Blank wells.

  5. 50 µL Nitrite Standard or Sample
  6.   Add 50 µL of Nitrite Standard or sample to the remaining wells.

  7. 50 µL Reaction Diluent (1X)
  8.   Add 50 µL of Reaction Diluent (1X) to all wells.

  9. 50 µL Griess Reagent I
  10.   Add 50 µL of Griess Reagent I to all wells.

  11. 50 µL Griess Reagent II
  12.   Add 50 µL of Griess Reagent II to all wells. Mix by gently tapping the side of the plate.
  13.   Incubate at room temperature for 10 minutes. Read at 540 nm with wavelength correction at 690 nm.



Refer to the product for complete assay procedure.

This assay procedure measures total nitrite by converting nitrate to nitrite. To determine the nitrate concentration in the sample, the endogenous nitrite concentration measured from the Nitrite Assay Procedure must be subtracted from the converted nitrite concentration measured in this procedure. Bring all reagents and samples to room temperature before use. It is recommended that all samples and standards be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Reaction Diluent (1X)
  4.   Add 50 µL of Reaction Diluent (1X) to the Blank wells.

  5. 50 µL Nitrate Standard or Sample
  6.   Add 50 µL of Nitrate Standard or sample to the remaining wells.

  7. 25 µL NADH
  8.   Add 25 µL of NADH to all wells.

  9. 25 µL Nitrate Reductase
  10.   Add 25 µL of diluted Nitrate Reductase to all wells. Mix well, cover with a plate sealer, and incubate at 37 °C for 30 minutes.

  11. 50 µL Griess Reagent I
  12.   Add 50 µL of Griess Reagent I to all wells.

  13. 50 µL Griess Reagent II
  14.   Add 50 µL of Griess Reagent II to all wells. Mix by gently tapping the side of the plate.
  15.   Incubate at room temperature for 10 minutes. Read at 540 nm with wavelength correction at 690 nm.

Citations for Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

166 Citations: Showing 1 - 10
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  1. Effects of plant- and animal-based-protein meals for a day on serum nitric oxide and peroxynitrite levels in healthy young men
    Authors: Kaneko, T;Yoshioka, M;Kawahara, F;Nishitani, N;Mori, S;Park, J;Tarumi, T;Kosaki, K;Maeda, S;
    Endocrine journal
    Species: Human
    Sample Types: Serum
  2. Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-?1/NF-?B Axis
    Authors: Sun, R;Zhu, J;Sun, K;Gao, L;Zheng, B;Shi, J;
    International journal of medical sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  3. Individual cell types in C. elegans age differently and activate distinct cell-protective responses
    Authors: Roux, AE;Yuan, H;Podshivalova, K;Hendrickson, D;Kerr, R;Kenyon, C;Kelley, D;
    Cell reports
    Species: Rat
    Sample Types: Cell Culture Supenates
  4. Thrombin-Induced Microglia Activation Modulated through Aryl Hydrocarbon Receptors
    Authors: Sheu, ML;Pan, LY;Yang, CN;Sheehan, J;Pan, LY;You, WC;Wang, CC;Pan, HC;
    International journal of molecular sciences
  5. Nanonitrator: novel enhancer of inorganic nitrate's protective effects, predicated on swarm learning approach
    Authors: W Pan, G Hu, S Li, G Li, X Feng, Z Wu, D Zhang, L Qin, X Wang, L Hu, J Xu, L Hu, Y Jia, X Wen, J Wang, C Zhang, J Zhou, W Li, X Wang, Y Wang, S Wang
    Science bulletin, 2023-03-30;0(0):.
    Species: Rat
    Sample Types: Plasma
  6. Endothelial Function and Hypoxic-Hyperoxic Preconditioning in Coronary Surgery with a Cardiopulmonary Bypass: Randomized Clinical Trial
    Authors: Mandel, IA;Podoksenov, YK;Mikheev, SL;Suhodolo, IV;Svirko, YS;Shipulin, VM;Ivanova, AV;Yavorovskiy, AG;Yaroshetskiy, AI;
    Biomedicines
    Species: Human
    Sample Types: Plasma
  7. Plantamajoside suppresses the activation of NF-kappaB and MAPK and ameliorates the development of osteoarthritis
    Authors: S Lin, J Lu, Q Chen, H Jiang, C Lou, C Lin, W Wang, J Lin, X Pan, X Xue
    International immunopharmacology, 2022-12-28;115(0):109582.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Effects of Thymoquinone Alone or in Combination with Losartan on the Cardiotoxicity Caused by Oxidative Stress and Inflammation in Hypercholesterolemia
    Authors: ZH Al-Oanzi, FO Alenazy, HH Alhassan, MR El-Aassar, AI Alzarea, SI Alzarea, AM Abbas, MH Alanazi, MM Al-Enazi
    Journal of cardiovascular development and disease, 2022-12-01;9(12):.
    Species: Rat
    Sample Types: Serum
  9. Anti-Inflammatory Effect of Sparstolonin B through Inhibiting Expression of NF-kappaB and STAT-1
    Authors: N Kim, C Kim, SH Ryu, GO Kim, JS Bae
    International Journal of Molecular Sciences, 2022-09-06;23(18):.
    Species: Human
    Sample Types: Cell Culture Supernates
  10. Integrated comparative metabolomics and network pharmacology approach to uncover the key active ingredients of Polygonati rhizoma and their therapeutic potential for the treatment of Alzheimer's disease
    Authors: F Wang, H Chen, Y Hu, L Chen, Y Liu
    Frontiers in Pharmacology, 2022-08-04;13(0):934947.
    Species: Rat
    Sample Types: Cell Culture Supernatants
  11. Sulfaphenazole reduces thermal and�pressure injury severity through rapid restoration of tissue perfusion
    Authors: CT Turner, M Pawluk, J Bolsoni, MR Zeglinski, Y Shen, H Zhao, T Ponomarev, KC Richardson, CR West, A Papp, DJ Granville
    Scientific Reports, 2022-07-23;12(1):12622.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Lipophilic Bioactive Compounds Transported in Triglyceride-Rich Lipoproteins Modulate Microglial Inflammatory Response
    Authors: JM Espinosa, JM Castellano, S Garcia-Rod, A Quintero-F, N Carrasquil, JS Perona
    International Journal of Molecular Sciences, 2022-07-12;23(14):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Time-dependent relationships between exercise training-induced changes in nitric oxide production and hormone regulation
    Authors: S Fujie, K Sanada, T Hamaoka, M Iemitsu
    Oncogene, 2022-07-09;166(0):111888.
    Species: Human
    Sample Types: Plasma
  14. Neutrophils and Circulating Inflammatory Biomarkers in Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction
    Authors: D Chaar, BL Dumont, B Vulesevic, PE Neagoe, A Räkel, M White, MG Sirois
    The American journal of cardiology, 2022-07-08;0(0):.
    Species: Human
    Sample Types: Plasma
  15. Plasma Endothelial and Oxidative Stress Biomarkers Associated with Late Mortality in Hospitalized COVID-19 Patients
    Authors: A Orea-Tejad, C Sánchez-Mo, OG Aztatzi-Ag, MP Sierra-Var, D González-I, Y Debray-Gar, MS Ortega-Rom, C Keirns-Dav, L Cornejo-Co, J Aguilar-Me
    Journal of Clinical Medicine, 2022-07-07;11(14):.
    Species: Human
    Sample Types: Plasma
  16. Gasdermin D-mediated microglial pyroptosis exacerbates neurotoxicity of aflatoxins B1 and M1 in mouse primary microglia and neuronal cultures
    Authors: J Zhang, D Su, Q Liu, Q Yuan, Z Ouyang, Y Wei, C Xiao, L Li, C Yang, W Jiang, L Guo, T Zhou
    Neurotoxicology, 2022-06-15;91(0):305-320.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  17. Influence of Malignant Pleural Fluid from Lung Adenocarcinoma Patients on Neutrophil Response
    Authors: M Mulet, R Osuna-Góme, C Zamora, JM Porcel, JC Nieto, L Perea, V Pajares, AM Muñoz-Fern, N Calvo, MA Sorolla, S Vidal
    Cancers, 2022-05-20;14(10):.
    Species: Human
    Sample Types: Pleural Fluid
  18. Aerobic exercise training-induced follistatin-like 1 secretion in the skeletal muscle is related to arterial stiffness via arterial NO production in obese rats
    Authors: K Inoue, S Fujie, N Horii, H Yamazaki, M Uchida, M Iemitsu
    Physiological Reports, 2022-05-01;10(10):e15300.
    Species: Rat
    Sample Types: Whole Blood
  19. Lipopolysaccharide-induced inflammation increases nitric oxide production in taste buds
    Authors: Z Wu, Y Huang, W Hu, L Ren, P Jiang, RF Margolskee, H Wang, S Feng
    Brain, Behavior, and Immunity, 2022-04-18;103(0):145-153.
    Species: Mouse
    Sample Types: Cell Culture Media
  20. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer
    Authors: MM LaRue, S Parker, J Puccini, M Cammer, AC Kimmelman, D Bar-Sagi
    Proceedings of the National Academy of Sciences of the United States of America, 2022-04-11;119(16):e2119168119.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  21. Eight Days of L-Citrulline or L-Arginine Supplementation Did Not Improve 200-m and 100-m Swimming Time Trials
    Authors: O Esen, MC Eser, M Abdioglu, D Benesova, T Gabrys, R Karayigit
    International Journal of Environmental Research and Public Health, 2022-04-07;19(8):.
    Species: Human
    Sample Types: Plasma
  22. Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury
    Authors: T Genovese, A Duranti, R D'Amico, R Fusco, D Impellizze, AF Peritore, R Crupi, E Gugliandol, S Cuzzocrea, R Di Paola, R Siracusa, M Cordaro
    International Journal of Molecular Sciences, 2022-03-03;23(5):.
    Species: Mouse
    Sample Types: Alveolar Fluid
  23. Endothelial MicroRNA-483-3p Is Hypertension-Protective
    Authors: F Shang, X Guo, Y Chen, C Wang, J Gao, E Wen, B Lai, L Bai
    Oxidative Medicine and Cellular Longevity, 2022-02-17;2022(0):3698219.
    Species: Human
    Sample Types: Serum
  24. Intravenous Arginine Administration Attenuates the Inflammatory Response and Improves Metabolic Profiles in Diet-Induced Obese Mice after Sleeve Gastrectomy
    Authors: YL Chen, MT Lin, WH Wang, SL Yeh, CL Yeh
    Metabolites, 2022-02-07;12(2):.
    Species: Mouse
    Sample Types: Plasma
  25. Exacerbation of Thrombotic Responses to Silver Nanoparticles in Hypertensive Mouse Model
    Authors: Z Ferdous, S Beegam, NE Zaaba, O Elzaki, S Tariq, YE Greish, BH Ali, A Nemmar
    Oxidative Medicine and Cellular Longevity, 2022-01-15;2022(0):2079630.
    Species: Mouse
    Sample Types: Plasma
  26. The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
    Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
    Biomedicines, 2022-01-04;10(1):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. Changes of plasma nitric oxide, endothelin-1, and blood coagulation following intravitreal conbercept
    Authors: QY Yi, LS Chen, Y Shen, YH Liao, YY Wang, J Yang, Y Jin, L Cheng
    Scientific Reports, 2021-12-13;11(1):23885.
    Species: Human
    Sample Types: Plasma
  28. Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells
    Authors: B Zhou, GT Jiang, H Liu, M Guo, J Liu, J She
    Nutrients, 2021-11-17;13(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Panaxynol induces fibroblast-like synovial cell apoptosis, inhibits proliferation and invasion through TLR4/NF-kappaB pathway to alleviate rheumatoid arthritis
    Authors: Y Zhao, X Sun, J Lin, T Zhang, S Liu, Z Yan
    International immunopharmacology, 2021-11-03;101(0):108321.
    Species: Rat
    Sample Types: Cell Culture Supernates
  30. Inhibitory effects of modified gamgil-tang in a particulate matter-induced lung injury mouse model
    Authors: YR Lyu, WK Yang, SW Lee, SH Kim, DS Kim, E Son, IC Jung, YC Park
    Journal of ethnopharmacology, 2021-10-30;284(0):114789.
    Species: Mouse
    Sample Types: BALF
  31. Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis
    Authors: E Román, M Poca, G Amorós-Fig, J Rosell-Fer, C Gely, JC Nieto, S Vidal, E Urgell, A Ferrero-Gr, E Alvarado-T, B Cuyàs, E Hernández, R Santesmase, C Guarner, À Escorsell, G Soriano
    Scientific Reports, 2021-10-14;11(1):20415.
    Species: Human
    Sample Types: Whole Blood
  32. Antioxidant and Anti-Inflammatory Properties of Bioavailable Protein Hydrolysates from Lupin-Derived Agri-Waste
    Authors: S Montserrat, A Villanueva, J Pedroche, F Millan, ME Martin, MC Millan-Lin
    Biomolecules, 2021-10-04;11(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  33. Aerobic Exercise Restores Aging-Associated Reductions in Arterial Adropin Levels and Improves Adropin-Induced Nitric Oxide-Dependent Vasorelaxation
    Authors: S Fujie, N Hasegawa, N Horii, M Uchida, K Sanada, T Hamaoka, J Padilla, LA Martinez-L, S Maeda, M Iemitsu
    Journal of the American Heart Association, 2021-05-03;0(0):e020641.
    Species: Human, Mouse
    Sample Types: Plasma
  34. P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
    Authors: E Yeini, P Ofek, S Pozzi, N Albeck, D Ben-Shusha, G Tiram, S Golan, R Kleiner, R Sheinin, S Israeli Da, S Reich-Zeli, R Grossman, Z Ram, H Brem, TM Hyde, P Magod, D Friedmann-, A Madi, R Satchi-Fai
    Nature Communications, 2021-03-26;12(1):1912.
    Species: Human
    Sample Types: Cell Culture Supernates
  35. Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice
    Authors: Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar
    NanoImpact, 2021-03-13;22(0):100310.
    Species: Mouse
    Sample Types: Tissue Homogenates
  36. All-trans-retinoic acid ameliorates atherosclerosis, promotes perivascular adipose tissue browning, and increases adiponectin production in Apo-E mice
    Authors: M Kalisz, M Chmielowsk, L Marty?ska, A Doma?ska, W Bik, A Litwiniuk
    Scientific Reports, 2021-02-24;11(1):4451.
    Species: Mouse
    Sample Types: Tissue Homogenates
  37. Dexamethasone increased the survival rate in Plasmodium berghei-infected mice
    Authors: DR Moreira, ACMG Uberti, ARQ Gomes, MES Ferreira, A da Silva B, ELP Varela, MF Dolabela, S Percário
    Scientific Reports, 2021-01-29;11(1):2623.
    Species: Mouse
    Sample Types: Tissue Homogenates
  38. Venous and Arterial Endothelial Cells from Human Umbilical Cords: Potential Cell Sources for Cardiovascular Research
    Authors: S Lau, M Gossen, A Lendlein, F Jung
    International Journal of Molecular Sciences, 2021-01-19;22(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  39. Impairment of IGF-1 Signaling and Antioxidant Response Are Associated with Radiation Sensitivity and Mortality
    Authors: S Y Aghdam, D Kenchegowd, GP Holmes-Ham, M Moroni, S P Ghosh
    International Journal of Molecular Sciences, 2021-01-05;22(1):.
    Species: Mouse
    Sample Types: Serum
  40. Cystathionine &gamma-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis
    Authors: R Bok, DD Guerra, RA Lorca, SA Wennersten, PS Harris, AK Rauniyar, SP Stabler, KN MacLean, JR Roede, LD Brown, KJ Hurt
    Redox Biology, 2020-12-08;40(0):101827.
    Species: Mouse
    Sample Types: Serum
  41. Pre-exposure to mechanical ventilation and endotoxemia increases Pseudomonas aeruginosa growth in lung tissue during experimental porcine pneumonia
    Authors: J Sperber, A Nyberg, A Krifors, P Skorup, M Lipcsey, M Castegren
    PLoS ONE, 2020-10-27;15(10):e0240753.
    Species: Porcine
    Sample Types: Urine
  42. Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells
    Authors: JH Song, DY Eum, SY Park, YH Jin, JW Shim, SJ Park, MY Kim, SJ Park, K Heo, YJ Choi
    PLoS ONE, 2020-10-22;15(10):e0240533.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. &alpha-Bisabolol, a Dietary Bioactive Phytochemical Attenuates Dopaminergic Neurodegeneration through Modulation of Oxidative Stress, Neuroinflammation and Apoptosis in Rotenone-Induced Rat Model of Parkinson's disease
    Authors: H Javed, MFN Meeran, S Azimullah, L Bader Eddi, VD Dwivedi, NK Jha, S Ojha
    Biomolecules, 2020-10-08;10(10):.
    Species: Rat
    Sample Types: Tissue Homogenates
  44. Computational Analysis of Clinical and Molecular Markers and New Theranostic Possibilities in Primary Open-Angle Glaucoma
    Authors: MD Pinazo-Dur, JJ García-Med, JM Bolarín, SM Sanz-Gonzá, M Valero-Vel, J Abellán-Ab, V Zanón-More, J Moreno-Mon
    Journal of Clinical Medicine, 2020-09-21;9(9):.
    Species: Human
    Sample Types: Aqueous Humor
  45. L-Arginine/Nitric Oxide Pathway Is Altered in Colorectal Cancer and Can Be Modulated by Novel Derivatives from Oxicam Class of Non-Steroidal Anti-Inflammatory Drugs
    Authors: M Krzystek-K, B Szcz??niak, I Szczuka, P Fortuna, M Zawadzki, A Kubiak, M Mierzcha?a, MG Fleszar, ? Lewandowsk, P Serek, N Jamrozik, K Neubauer, J Wi?niewski, R Kempi?ski, W Witkiewicz, I Bednarz-Mi
    Cancers (Basel), 2020-09-11;12(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  46. Increase of Cardiometabolic Biomarkers Among Vehicle Inspectors Exposed to PM0.25 and Compositions
    Authors: DH Ramdhan, F Kurniasari, M Tejamaya, A Fitri, A Indriani, A Kusumaward, M Santoso
    Safety and health at work, 2020-08-29;12(1):114-118.
    Species: Human
    Sample Types: Plasma
  47. Exercise-Induced Elevated BDNF Level Does Not Prevent Cognitive Impairment Due to Acute Exposure to Moderate Hypoxia in Well-Trained Athletes
    Authors: Z Piotrowicz, M Chalimoniu, K P?oszczyca, M Czuba, J Langfort
    Int J Mol Sci, 2020-08-04;21(15):.
    Species: Human
    Sample Types: Serum
  48. Silencing of long non-coding RNA Sox2ot inhibits oxidative stress and inflammation of vascular smooth muscle cells in abdominal aortic aneurysm via microRNA-145-mediated Egr1 inhibition
    Authors: H Lin, B You, X Lin, X Wang, D Zhou, Z Chen, Y Chen, R Wang
    Aging (Albany NY), 2020-07-06;12(13):12684-12702.
    Species: Mouse
    Sample Types: Serum
  49. MiR-22-3p suppresses sepsis-induced acute kidney injury by targeting PTEN
    Authors: X Wang, Y Wang, M Kong, J Yang
    Biosci. Rep., 2020-06-26;40(6):.
    Species: Human, Rat
    Sample Types: Cell Culture Supernates, Serum
  50. Secretome of Hypoxic Endothelial Cells Stimulates Bone Marrow-Derived Mesenchymal Stem Cells to Enhance Alternative Activation of Macrophages
    Authors: KJ Chou, CY Hsu, CW Huang, HY Chen, SH Ou, CL Chen, PT Lee, HC Fang
    Int J Mol Sci, 2020-06-21;21(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Synergistic Effects of Moderate Therapeutic Hypothermia and Levosimendan on Cardiac Function and Survival After Asphyxia-Induced Cardiac Arrest in Rats
    Authors: CH Wang, WT Chang, MS Tsai, CH Huang, WJ Chen
    J Am Heart Assoc, 2020-06-01;0(0):e016139.
    Species: Rat
    Sample Types: Plasma
  52. Combination of Red Clover and Hops Extract Improved Menopause Symptoms in an Ovariectomized Rat Model
    Authors: MR Kim, HJ Kim, SH Yu, BS Lee, SY Jeon, JJ Lee, YC Lee
    Evid Based Complement Alternat Med, 2020-05-23;2020(0):7941391.
    Species: Rat
    Sample Types: Serum
  53. Imbalance Between Oxidative Stress and Growth Factors in Human High Myopia
    Authors: S Mérida, VM Villar, A Navea, C Desco, M Sancho-Tel, C Peris, F Bosch-More
    Front Physiol, 2020-05-14;11(0):463.
    Species: Human
    Sample Types: Aqueous Humor
  54. Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis
    Authors: SA Tanusepute, MT Lin, SL Yeh, CL Yeh
    Mediators Inflamm., 2020-05-11;2020(0):3201635.
    Species: Mouse
    Sample Types: Plasma
  55. Reevaluation of Lung Injury in TNF-Induced Shock: The Role of the Acid Sphingomyelinase
    Authors: LK Reiss, U Raffetsede, L Gibbert, HK Drescher, KL Streetz, A Schwarz, C Martin, S Uhlig, D Adam
    Mediators Inflamm., 2020-05-01;2020(0):3650508.
    Species: Mouse
    Sample Types: Plamsa
  56. The Role of High Fat Diets and Liver Peptidase Activity in the Development of Obesity and Insulin Resistance in Wistar Rats
    Authors: G Domínguez-, AB Segarra, M Ramírez-Sá, I Prieto
    Nutrients, 2020-02-28;12(3):.
    Species: Rat
    Sample Types: Plasma
  57. iNOS regulates the therapeutic response of pancreatic cancer cells to radiation therapy
    Authors: PMR Pereira, KJ Edwards, K Mandleywal, LM Carter, FE Escorcia, LF Campesato, M Cornejo, L Abma, AA Mohsen, CA Iacobuzio-, T Merghoub, JS Lewis
    Cancer Res., 2020-02-21;0(0):.
    Species: Human, Mouse
    Sample Types: Cell Culture Supernates
  58. Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection
    Authors: N Steffens, C Beuter-Gun, E Kravets, A Reich, L Legewie, K Pfeffer, D Degrandi
    MBio, 2020-01-21;11(1):.
    Species: Mouse
    Sample Types: Serum
  59. Comparative Study on Pulmonary Toxicity in Mice Induced by Exposure to Unflavoured and Apple- and Strawberry-Flavoured Tobacco Waterpipe Smoke
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
    Oxid Med Cell Longev, 2020-01-14;2020(0):6450450.
    Species: Mouse
    Sample Types: Tissue Homogenates
  60. N-acetyl cysteine attenuates oxidative stress and glutathione-dependent redox imbalance caused by high glucose/high palmitic acid treatment in pancreatic Rin-5F cells
    Authors: A Alnahdi, A John, H Raza
    PLoS ONE, 2019-12-20;14(12):e0226696.
    Species: Rat
    Sample Types: Cell Culture Superantes
  61. Effect of atorvastatin on pulmonary arterial hypertension in rats through PI3K/AKT signaling pathway
    Authors: YY Wang, XD Cheng, H Jiang
    Eur Rev Med Pharmacol Sci, 2019-12-01;23(23):10549-10556.
    Species: Rat
    Sample Types: Serum
  62. A macromolecular alpha-glucan from fruiting bodies of Volvariella volvacea activating RAW264. 7 macrophages through MAPKs pathway
    Authors: F Cui, L Jiang, L Qian, W Sun, T Tao, X Zan, Y Yang, D Wu, X Zhao
    Carbohydr Polym, 2019-11-26;230(0):115674.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. Vitamin e-loaded membrane dialyzers reduce hemodialysis inflammaging
    Authors: V Sepe, M Gregorini, T Rampino, P Esposito, R Coppo, F Galli, C Libetta
    BMC Nephrol, 2019-11-15;20(1):412.
    Species: Human
    Sample Types: Serum
  64. In deep evaluation of the neurotoxicity of orally administered TiO2 nanoparticles
    Authors: I Grissa, J ElGhoul, R Mrimi, LE Mir, HB Cheikh, P Horcajada
    Brain Res. Bull., 2019-11-09;0(0):.
    Species: Rat
    Sample Types: Tissue Lysates
  65. Genome sequence data announcement of Bifidobacterium bifidum strain ICIS-202 isolated from a healthy human intestine stimulating active nitrogen oxide production in macrophages
    Authors: OV Bukharin, SV Andryusche, NB Perunova, EV Ivanova, IN Chainikova, IA Zdvizhkova
    Data Brief, 2019-11-06;27(0):104761.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  66. Comparison of the Effectiveness of High-Intensity Interval Training in Hypoxia and Normoxia in Healthy Male Volunteers: A Pilot Study
    Authors: A ?ebrowska, D Jastrz?bsk, E Sadowska-K, M Sikora, C Di Giulio
    Biomed Res Int, 2019-09-22;2019(0):7315714.
    Species: Human
    Sample Types: Serum
  67. Impaired microvascular reactivity after eccentric muscle contractions is not restored by acute ingestion of antioxidants or dietary nitrate
    Authors: RG Larsen, JM Thomsen, RP Hirata, R Steffensen, ER Poulsen, JB Frøkjaer, T Graven-Nie
    Physiol Rep, 2019-07-01;7(13):e14162.
    Species: Human
    Sample Types: Plasma
  68. Testicular Toxicity of Water Pipe Smoke Exposure in Mice and the Effect of Treatment with Nootkatone Thereon
    Authors: BH Ali, S Al-Salam, SA Adham, K Al Balushi, M Al Za'abi, S Beegam, P Yuvaraju, P Manoj, A Nemmar
    Oxid Med Cell Longev, 2019-06-25;2019(0):2416935.
    Species: Mouse
    Sample Types: Tissue Homogenates
  69. Coronary circulating mononuclear progenitor cells and soluble biomarkers in the cardiovascular prognosis after coronary angioplasty
    Authors: JA Suárez-Cue, R Robledo-No, MA Alcántara-, LJ Díaz Herná, E Vera-Gómez, A Hernández-, KS Sánchez-Dí, JA Buendía-Gu, A Contreras-, AS Ruíz-Herná, R Pérez-Cabe, P Mondragón-
    J. Cell. Mol. Med., 2019-05-08;0(0):.
    Species: Human
    Sample Types: Plasma
  70. Uncoupling Protein 2 Increases Blood Pressure in DJ -1 Knockout Mice
    Authors: C De Miguel, WC Hamrick, R Sedaka, S Jagarlamud, LD Asico, PA Jose, S Cuevas
    J Am Heart Assoc, 2019-05-07;8(9):e011856.
    Species: Mouse
    Sample Types: Serum
  71. Effects of propofol on the inflammatory response during robot-assisted laparoscopic radical prostatectomy: a prospective randomized controlled study
    Authors: GU Roh, Y Song, J Park, YM Ki, DW Han
    Sci Rep, 2019-03-27;9(1):5242.
    Species: Human
    Sample Types: Serum
  72. Modified lipoproteins in periodontitis: a link to cardiovascular disease?
    Authors: S Ljunggren, T Bengtsson, H Karlsson, C Starkhamma, E Palm, F Nayeri, B Ghafouri, J Davies, G Svensäter, J Lönn
    Biosci. Rep., 2019-03-26;39(3):.
    Species: Human
    Sample Types: Serum
  73. Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water-Pipe Smoke Exposure in Mice
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
    Front Physiol, 2019-02-25;10(0):53.
    Species: Mouse
    Sample Types: Tissue Homogenates
  74. Effects of maternal dietary nitrate supplementation on farrowing and placental characteristics, level of asphyxiation at birth and piglet vitality
    Authors: M van den Bo, J Wijnen, IB van de Lin, AAM van Wesel, D Melchior, B Kemp, H van den Br, C Clouard
    Theriogenology, 2019-02-12;129(0):1-7.
    Species: Porcine
    Sample Types: Plasma
  75. High drug payload nanoparticles formed from dexamethasone-peptide conjugates for the treatment of endotoxin-induced uveitis in rabbit
    Authors: X Yu, R Zhang, L Lei, Q Song, X Li
    Int J Nanomedicine, 2019-01-14;14(0):591-603.
    Species: Human
    Sample Types: Cell Culture Supernates
  76. Vascular and hemostatic alterations associated with pulmonary hypertension in ?-thalassemia hemoglobin E patients receiving regular transfusion and iron chelation
    Authors: N Uaprasert, S Satitthumm, B Akkawat, P Sutcharitc, P Rojnuckari
    Thromb. Res., 2018-12-20;174(0):104-112.
    Species: Human
    Sample Types: Plasma
  77. Cytoprotective Effects of N-Acetylcysteine on Streptozotocin- Induced Oxidative Stress and Apoptosis in RIN-5F Pancreatic ?-Cells
    Authors: AMT Al-Nahdi, A John, H Raza
    Cell. Physiol. Biochem., 2018-11-16;51(1):201-216.
    Species: Rat
    Sample Types: Cell Culture Supernates
  78. Morphological changes, nitric oxide production, and phagocytosis are triggered in vitro in microglia by bloodstream forms of Trypanosoma brucei
    Authors: K Figarella, NL Uzcategui, S Mogk, K Wild, P Fallier-Be, JJ Neher, M Duszenko
    Sci Rep, 2018-10-09;8(1):15002.
    Species: Mouse, Parasite - Trypanosoma brucei
    Sample Types: Cell Culture Supernates
  79. Different aspects of platelet evaluation in dengue: measurement of circulating mediators, ability to interact with the virus, the degree of activation and quantification of intraplatelet protein content
    Authors: TA da Costa B, D de Oliveir, AT de Carvalh, NR da Costa F, DF Barreto-Vi, F Cunha Jáco, OM Barth, RMR Nogueira, PC da Costa N, DC de Souza M, EL de Azeredo, PV Damasco, RV da Cunha, LM de-Oliveir
    Virus Res., 2018-09-30;0(0):.
    Species: Human
    Sample Types: Plasma
  80. The effect of sodium nitrite infusion on renal function, brachial and central blood pressure during enzyme inhibition by allopurinol, enalapril or acetazolamide in healthy subjects: a randomized, double-blinded, placebo-controlled, crossover study
    Authors: JB Rosenbaek, EB Pedersen, JN Bech
    BMC Nephrol, 2018-09-21;19(1):244.
    Species: Human
    Sample Types: Plasma
  81. The Protective Effect of Ligustilide in Osteoarthritis: An in Vitro and in Vivo Study
    Authors: X Li, D Wu, Z Hu, J Xuan, X Ding, G Zheng, Z Feng, W Ni, A Wu
    Cell. Physiol. Biochem., 2018-08-17;48(6):2583-2595.
    Species: Human
    Sample Types: Cell Culture Supernates
  82. Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite
    Authors: N Li, C Wang, S Sun, C Zhang, D Lü, Q Chen, M Long
    Front Physiol, 2018-07-31;9(0):1025.
    Species: Human
    Sample Types: Cell Culture Supernates
  83. Protective effect and mechanism of rat recombinant S100 calcium-binding protein A4 on oxidative stress injury of rat vascular endothelial cells
    Authors: X Meng, X Gao, Z Zhang, X Zhou, L Wu, M Yang, K Wang, H Ren, B Sun, T Wang
    Oncol Lett, 2018-07-11;16(3):3614-3622.
    Species: Rat
    Sample Types: Cell Culture Supernates
  84. Beneficial role of virgin coconut oil supplementation against acute methotrexate chemotherapy-induced oxidative toxicity and inflammation in rats
    Authors: AC Famurewa, AM Folawiyo, EB Enohnyaket, SO Azubuike-O, I Abi, SG Obaje, OA Famurewa
    Integr Med Res, 2018-05-14;7(3):257-263.
    Species: Rat
    Sample Types: Serum
  85. Hybrids of carbon dots with subunit B of ricin toxin for enhanced immunomodulatory activity
    Authors: Y Li, W Liu, C Sun, M Zheng, J Zhang, B Liu, Y Wang, Z Xie, N Xu
    J Colloid Interface Sci, 2018-03-30;523(0):226-233.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Arginine pretreatment enhances circulating endothelial progenitor cell population and attenuates inflammatory response in high-fat diet-induced obese mice with limb ischemia
    Authors: YF Kuo, CL Yeh, JM Shih, YM Shih, SL Yeh
    Nutr Res, 2018-03-23;0(0):.
    Species: Mouse
    Sample Types: Plasma
  87. Effects of fish and krill oil on gene expression in peripheral blood mononuclear cells and circulating markers of inflammation: a randomised controlled trial
    Authors: A Rundblad, KB Holven, I Bruheim, MC Myhrstad, SM Ulven
    J Nutr Sci, 2018-03-21;7(0):e10.
    Species: Human
    Sample Types: Serum
  88. Bioactive Cembranoids from the Soft Coral Genus Sinularia sp. in Borneo
    Authors: T Kamada, MC Kang, CS Phan, II Zanil, YJ Jeon, CS Vairappan
    Mar Drugs, 2018-03-21;16(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  89. In Vivo Protective Effects of Nootkatone against Particles-Induced Lung Injury Caused by Diesel Exhaust Is Mediated via the NF-?B Pathway
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, N Hamadi, BH Ali
    Nutrients, 2018-02-26;10(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  90. Cardiac effects of fish oil in a rat model of streptozotocin-induced diabetes
    Authors: F Mayyas, R Jaradat, KH Alzoubi
    Nutr Metab Cardiovasc Dis, 2018-02-25;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  91. The effect of low and high-intensity cycling in diesel exhaust on flow-mediated dilation, circulating NOx, endothelin-1 and blood pressure
    Authors: LV Giles, SJ Tebbutt, C Carlsten, MS Koehle
    PLoS ONE, 2018-02-21;13(2):e0192419.
    Species: Human
    Sample Types: Plasma
  92. Effect of hypotensive therapy combined with modified diet or zinc supplementation on biochemical parameters and mineral status in hypertensive patients
    Authors: J Suliburska, K Skrypnik, M Szuli?ska, J Kupsz, P Bogda?ski
    J Trace Elem Med Biol, 2018-02-18;47(0):140-148.
    Species: Human
    Sample Types: Serum
  93. Chronic hyperuricemia impairs blood flow recovery in the ischemic hindlimb through suppression of endothelial progenitor cells
    Authors: IC Chen, CS Kuo, CC Wu, HY Tsai, CP Lin, SY Li, RH Chou, PH Huang, JW Chen, SJ Lin
    Oncotarget, 2018-01-22;9(10):9285-9298.
    Species: Mouse
    Sample Types: Serum
  94. Isolated kidney perfusion: the influence of pulsatile flow
    Authors: C von Horn, T Minor
    Scand. J. Clin. Lab. Invest., 2018-01-04;0(0):1-5.
    Species: Porcine
    Sample Types: Tissue Homogenates
  95. The Potential Therapeutic Role of Peroxisome ProliferatorActivated Receptors Agonist in Preeclamptic Pregnant Rats
    Authors: HIG Allam, AAA Masri
    J Coll Physicians Surg Pak, 2018-01-01;28(1):31-35.
    Species: Rat
    Sample Types: Plasma
  96. Functional status of microvascular vasomotion is impaired in spontaneously hypertensive rat
    Authors: M Liu, X Zhang, B Wang, Q Wu, B Li, A Li, H Zhang, R Xiu
    Sci Rep, 2017-12-06;7(1):17080.
    Species: Rat
    Sample Types: Cell Culture Supernates
  97. Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-?B and HMGB1 pathways through the upregulation of SIRT1
    Authors: KC Lan, SC Chao, HY Wu, CL Chiang, CC Wang, SH Liu, TI Weng
    Sci Rep, 2017-09-20;7(1):12026.
    Species: Mouse
    Sample Types: Serum
  98. Effects of anti-lipid peroxidation of Punica granatum fruit extract in endothelial cells induced by plasma of severe pre-eclamptic patients
    Authors: I Nasifah, S Soeharto, M Nooryanto
    J Ayurveda Integr Med, 2017-09-15;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic ?-Cells
    Authors: AMTA Nahdi, A John, H Raza
    Oxid Med Cell Longev, 2017-08-06;2017(0):7054272.
    Species: Rat
    Sample Types: Cell Culture Supernates
  100. Citrulline decreases hepatic endotoxin-induced injury in fructose-induced non-alcoholic liver disease: an ex vivo study in the isolated perfused rat liver
    Authors: W Ouelaa, P Jegatheesa, J M'bouyou-B, C Vicente, S Nakib, E Nubret, JP De Bandt
    Br. J. Nutr., 2017-06-22;0(0):1-8.
    Species: Rat
    Sample Types: Liver Perfusate
  101. Cynanchum wilfordii Polysaccharides Suppress Dextran Sulfate Sodium-Induced Acute Colitis in Mice and the Production of Inflammatory Mediators from Macrophages
    Authors: CW Cho, S Ahn, TG Lim, HD Hong, YK Rhee, DC Yang, M Jang
    Mediators Inflamm., 2017-06-20;2017(0):3859856.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  102. The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches
    Authors: RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So
    PLoS ONE, 2017-06-08;12(6):e0179174.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. Danhong Huayu Koufuye Prevents Diabetic Retinopathy in Streptozotocin-Induced Diabetic Rats via Antioxidation and Anti-Inflammation
    Authors: W Chen, X Yao, C Zhou, Z Zhang, G Gui, B Lin
    Mediators Inflamm., 2017-05-30;2017(0):3059763.
    Species: Rat
    Sample Types: Serum
  104. Benzo[a]pyrene activates interleukin-6 induction and suppresses nitric oxide-induced apoptosis in rat vascular smooth muscle cells
    Authors: HP Tzeng, KC Lan, TH Yang, MN Chung, SH Liu
    PLoS ONE, 2017-05-22;12(5):e0178063.
    Species: Rat
    Sample Types: Cell Culture Supernates
  105. Intravenous Arginine Administration Promotes Proangiogenic Cells Mobilization and Attenuates Lung Injury in Mice with Polymicrobial Sepsis
    Authors: CL Yeh, MH Pai, YM Shih, JM Shih, SL Yeh
    Nutrients, 2017-05-17;9(5):.
    Species: Mouse
    Sample Types: Plasma
  106. Prostate cancer downregulated SIRP-? modulates apoptosis and proliferation through p38-MAPK/NF-?B/COX-2 signaling
    Authors: C Yao, G Li, M Cai, Y Qian, L Wang, L Xiao, F Thaiss, B Shi
    Oncol Lett, 2017-04-21;13(6):4995-5001.
    Species: Human
    Sample Types: Cell Culture Supernates, Serum
  107. Defective Platelet Activation and Bleeding Complications upon Cholestasis in Mice
    Authors: NS Gowert, M Klier, M Reich, F Reusswig, L Donner, V Keitel, D Häussinger, M Elvers
    Cell. Physiol. Biochem., 2017-04-20;41(6):2133-2149.
    Species: Mouse
    Sample Types: Plasma
  108. Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis
    Authors: P Piñero, O Juanola, E Caparrós, P Zapater, P Giménez, JM González-N, J Such, R Francés
    Sci Rep, 2017-04-18;7(0):46425.
    Species: Human
    Sample Types: Serum
  109. CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation-resistant tissues
    Authors: Farshid Guilak
    Arthritis & rheumatology, 2017-03-31;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  110. Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice
    Authors: A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali
    Oxid Med Cell Longev, 2017-03-14;2017(0):9639035.
    Species: Mouse
    Sample Types: Tissue Homogenates
  111. Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial
    Authors: VK Snowdon, NJ Lachlan, AM Hoy, PW Hadoke, SI Semple, D Patel, W Mungall, TJ Kendall, A Thomson, RJ Lennen, MA Jansen, CM Moran, A Pellicoro, P Ramachandr, I Shaw, RL Aucott, T Severin, R Saini, J Pak, D Yates, N Dongre, JS Duffield, DJ Webb, JP Iredale, PC Hayes, JA Fallowfiel
    PLoS Med, 2017-02-28;14(2):e1002248.
    Species: Human, Rat
    Sample Types: Serum
  112. Nitric Oxide Synthase Trafficking Inducer is a pleiotropic regulator of endothelial cell function and signaling
    Authors: S Chakrabort, R Ain
    J. Biol. Chem, 2017-02-24;0(0):.
  113. Histological and Immunohistochemical Basis of the Effect of Aminoguanidine on Renal Changes Associated with Hemorrhagic Shock in a Rat Model
    Authors: A Al Drees, M Salah Khal, M Soliman
    Acta Histochem Cytochem, 2017-02-22;50(1):11-19.
    Species: Rat
    Sample Types: Plasma
  114. Exosomes from eosinophils autoregulate and promote eosinophil functions
    Authors: JA Ca¤as, B Sastre, C Mazzeo, M Fern ndez-, JM Rodrigo-Mu, A Gonz lez-G, M Izquierdo, P Barranco, S Quirce, J Sastre, V Del Pozo
    J. Leukoc. Biol, 2017-01-17;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  115. Inflammatory Mediators in Tracheal Aspirates of Preterm Infants Participating in a Randomized Trial of Inhaled Nitric Oxide
    Authors: M Laube, E Amann, U Uhlig, Y Yang, HW Fuchs, M Zemlin, JC Mercier, RF Maier, HD Hummler, S Uhlig, UH Thome
    PLoS ONE, 2017-01-03;12(1):e0169352.
    Species: Human
    Sample Types: Tissue Secretion
  116. Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression
    Authors: Jun Lu
    Brain Res. Bull, 2016-11-30;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  117. Hesperidin ameliorates immunological outcome and reduces neuroinflammation in the mouse model of multiple sclerosis
    Authors: Mahmoud Mahmoudi
    J. Neuroimmunol., 2016-11-26;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  118. Lectins from Synadenium carinatum (ScLL) and Artocarpus heterophyllus (ArtinM) Are Able to Induce Beneficial Immunomodulatory Effects in a Murine Model for Treatment of Toxoplasma gondii Infection
    Authors: EL Ramos, SS Santana, MV Silva, FM Santiago, TW Mineo, JR Mineo
    Front Cell Infect Microbiol, 2016-11-25;6(0):164.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  119. Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells
    Sci Rep, 2016-11-16;6(0):37095.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling
    PLoS ONE, 2016-11-04;11(11):e0165197.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  121. Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1?-Induced Inflammation and Apoptosis in Chondrocytes
    Biomed Res Int, 2016-10-30;2016(0):6290957.
    Species: Rat
    Sample Types: Cell Culture Supernates
  122. Irisin Lowers Blood Pressure by Improvement of Endothelial Dysfunction via AMPK-Akt-eNOS-NO Pathway in the Spontaneously Hypertensive Rat
    J Am Heart Assoc, 2016-10-26;5(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  123. Cytotoxicity of Silver Nanoparticle and Chitin-Nanofiber Sheet Composites Caused by Oxidative Stress
    Authors: J Kinoda, M Ishihara, H Hattori, S Nakamura, K Fukuda, H Yokoe
    Nanomaterials (Basel), 2016-10-20;6(10):.
    Species: Human
    Sample Types: Cell Lysates
  124. Physicochemistry and cardiovascular toxicity of metal fume PM2.5: a study of human coronary artery endothelial cells and welding workers
    Sci Rep, 2016-09-19;6(0):33515.
    Species: Human
    Sample Types: Cell Culture Supernates
  125. Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments
    Authors: Haiyan Peng
    J. Neuroimmunol, 2016-08-05;299(0):35-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  126. Endothelial Cell Response to Fusobacterium nucleatum.
    Authors: Mendes R, Pamuk F
    Infect Immun, 2016-06-23;84(7):2141-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. Impact of Genetic Polymorphism of methylenetetrahydrofolate reductase C677T on Development of Hyperhomocysteinemia and Related Oxidative Changes in Egyptian ?-Thalassemia Major Patients
    PLoS ONE, 2016-05-17;11(5):e0155070.
    Species: Human
    Sample Types: Plasma
  128. Aberrant Inflammasome Activation Characterizes Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome
    Authors: HY Tan, YK Yong, EM Shankar, G Paukovics, R Ellegård, M Larsson, A Kamarulzam, MA French, SM Crowe
    J Immunol, 2016-04-13;0(0):.
    Species: Human
    Sample Types: Plasma
  129. Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism.
    Authors: Chang T, Wu T, Huang P, Lin C, Chen J, Lin L, Lin S, Chen J
    PLoS ONE, 2015-08-25;10(8):e0136627.
    Species: Mouse
    Sample Types: Plasma
  130. The homeoprotein DLX4 controls inducible nitric oxide synthase-mediated angiogenesis in ovarian cancer.
    Authors: Trinh B, Ko S, Haria D, Barengo N, Naora H
    Mol Cancer, 2015-04-30;14(0):97.
    Species: Human
    Sample Types: Cell Culture Supernates
  131. Estradiol promotes M1-like macrophage activation through cadherin-11 to aggravate temporomandibular joint inflammation in rats.
    Authors: Kou X, Li C, He D, Wang X, Hao T, Meng Z, Zhou Y, Gan Y
    J Immunol, 2015-02-13;194(6):2810-8.
    Species: Rat
    Sample Types: Cell Culture Supernates
  132. Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT(2)R and cytoskeletal dysregulation.
    Authors: Chang K, Nayak R, Roy S, Perumbeti A, Wellendorf A, Bezold K, Pirman M, Hill S, Starnes J, Loberg A, Zhou X, Inagami T, Zheng Y, Malik P, Cancelas J
    Nat Commun, 2015-01-09;6(0):5914.
    Species: Mouse
    Sample Types: Plasma
  133. High levels of pigment epithelium-derived factor in diabetes impair wound healing through suppression of Wnt signaling.
    Authors: Qi W, Yang C, Dai Z, Che D, Feng J, Mao Y, Cheng R, Wang Z, He X, Zhou T, Gu X, Yan L, Yang X, Ma J, Gao G
    Diabetes, 2014-11-03;64(4):1407-19.
    Species: Mouse
    Sample Types: Plasma
  134. Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study.
    Authors: Lin L, Huang C, Chen J, Wu T, Leu H, Huang P, Chang T, Lin S, Chen J
    Cardiovasc Diabetol, 2014-07-16;13(0):111.
    Species: Human
    Sample Types: Serum
  135. Aspirin treatment improved mesenchymal stem cell immunomodulatory properties via the 15d-PGJ2/PPARgamma/TGF-beta1 pathway.
    Authors: Tang J, Xiong J, Wu T, Tang Z, Ding G, Zhang C, Wang S, Liu Y
    Stem Cells Dev, 2014-07-01;23(17):2093-103.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma.
    Authors: Voraphani N, Gladwin M, Contreras A, Kaminski N, Tedrow J, Milosevic J, Bleecker E, Meyers D, Ray A, Ray P, Erzurum S, Busse W, Zhao J, Trudeau J, Wenzel S
    Mucosal Immunol, 2014-02-12;7(5):1175-85.
    Species: Human
    Sample Types: Cell Culture Supernates
  137. Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
    Authors: Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S
    EMBO Mol Med, 2014-01-08;6(3):322-34.
    Species: Human
    Sample Types: Cell Culture Supernates
  138. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus.
    Authors: Cherney D, Perkins B, Soleymanlou N, Maione M, Lai V, Lee A, Fagan N, Woerle H, Johansen O, Broedl U, von Eynatten M
    Circulation, 2013-12-13;129(5):587-97.
    Species: Human
    Sample Types: Plasma
  139. Lung protective ventilation induces immunotolerance and nitric oxide metabolites in porcine experimental postoperative sepsis.
    Authors: Sperber J, Lipcsey M, Larsson A, Larsson A, Sjolin J, Castegren M
    PLoS ONE, 2013-12-12;8(12):e83182.
    Species: Porcine
    Sample Types: Urine
  140. Increase in the mediators of asthma in obesity and obesity with type 2 diabetes: reduction with weight loss.
    Authors: Dandona P, Ghanim H, Monte S, Caruana J, Green K, Abuaysheh S, Lohano T, Schentag J, Dhindsa S, Chaudhuri A
    Obesity (Silver Spring), 2013-09-04;22(2):356-62.
    Species: Human
    Sample Types: Plasma
  141. Comparison of drug and cell-based delivery: engineered adult mesenchymal stem cells expressing soluble tumor necrosis factor receptor II prevent arthritis in mouse and rat animal models.
    Authors: Liu L, Wang G, Hendricks K, Lee K, Bohnlein E, Junker U, Mosca J
    Stem Cells Transl Med, 2013-04-16;2(5):362-75.
    Species: Human
    Sample Types: Cell Culture Supernates
  142. Modulation of inflammatory response in a cirrhotic rat model with induced bacterial peritonitis.
    Authors: Sanchez E, Frances R, Soriano G, Mirelis B, Sancho F, Gonzalez-Navajas J, Munoz C, Song X, Perez-Mateo M, Such J, Guarner C
    PLoS ONE, 2013-03-20;8(3):e59692.
    Species: Rat
    Sample Types: Serum
  143. Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture.
    Authors: Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W, Van Dyck C
    Lab Invest, 2012-08-13;92(10):1428-39.
    Species: Rat
    Sample Types: Serum
  144. Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.
    J. Invest. Dermatol., 2012-06-21;132(11):2642-51.
    Species: Human
    Sample Types: Cell Culture Supernates
  145. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
    Authors: Barber DL, Mayer-Barber KD, Feng CG
    J. Immunol., 2010-12-20;186(3):1598-607.
    Species: Mouse
    Sample Types: BALF
  146. The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss.
    Authors: Liang S, Krauss JL, Domon H, McIntosh ML, Hosur KB, Qu H, Li F, Tzekou A, Lambris JD, Hajishengallis G
    J. Immunol., 2010-12-13;186(2):869-77.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  147. Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.
    Authors: Mayer-Barber KD, Barber DL, Shenderov K, White SD, Wilson MS, Cheever A, Kugler D, Hieny S, Caspar P, Nunez G, Schlueter D, Flavell RA, Sutterwala FS, Sher A
    J. Immunol., 2010-03-03;184(7):3326-30.
    Species: Mouse
    Sample Types: BALF
  148. Loss of ability to self-heal malaria upon taurine transporter deletion.
    Authors: Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishi S, Haussinger D, Wunderlich F
    Infect. Immun., 2010-01-25;78(4):1642-9.
    Species: Mouse
    Sample Types: Serum
  149. Molecular adsorbent recirculating system is ineffective in the management of type 1 hepatorenal syndrome in patients with cirrhosis with ascites who have failed vasoconstrictor treatment.
    Authors: Wong F, Raina N, Richardson R
    Gut, 2009-08-25;59(3):381-6.
    Species: Human
    Sample Types: Plasma
  150. Nox2-containing NADPH oxidase deficiency confers protection from hindlimb ischemia in conditions of increased oxidative stress.
    Authors: Haddad P, Dussault S, Groleau J, Turgeon J, Michaud SE, Menard C, Perez G, Maingrette F, Rivard A
    Arterioscler. Thromb. Vasc. Biol., 2009-07-02;29(10):1522-8.
    Species: Mouse
    Sample Types: Plasma
  151. Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukin-6-activated inducible nitric oxide synthase-related pathway.
    Authors: Weng TI, Wu HY, Lin PY, Liu SH
    Infect. Immun., 2009-05-26;77(8):3312-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  152. Endothelial nitric oxide synthase gene polymorphisms and Plasmodium falciparum infection in Indian adults.
    Authors: Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit M
    Infect. Immun., 2009-04-13;77(7):2943-7.
    Species: Human
    Sample Types: Plasma
  153. Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
    Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
    J Ethnopharmacol, 2009-02-03;122(3):473-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  154. Aerobic interval training reduces cardiovascular risk factors more than a multitreatment approach in overweight adolescents.
    Authors: Tjonna AE, Stolen TO, Bye A, Volden M, Slordahl SA, Odegard R, Skogvoll E, Wisloff U
    Clin. Sci., 2009-02-01;116(4):317-26.
    Species: Human
    Sample Types: Plasma
  155. Decreased nitric oxide products in the urine of patients undergoing cardiac surgery.
    Authors: Lema G, Urzua J, Jalil R, Canessa R, Vogel A, Moran S, Fajuri A, Carvajal C, Aeschlimann N, Jaque MP
    J. Cardiothorac. Vasc. Anesth., 2008-11-20;23(2):188-94.
    Species: Human
    Sample Types: Urine
  156. Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function.
    Authors: Hajishengallis G, Wang M, Liang S, Triantafilou M, Triantafilou K
    Proc. Natl. Acad. Sci. U.S.A., 2008-09-02;105(36):13532-7.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  157. Leptin, blood pressure, and aerobic capacity in women.
    Authors: Sabatier MJ, McCully KK, Marinik EL, Schwark EH, Haddow S, Cortez-Cooper M, Bergeron MF, Sloan GJ, Cannon JG
    Am. J. Hypertens., 2008-08-28;21(11):1245-50.
    Species: Human
    Sample Types: Serum
  158. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study.
    Authors: Tjonna AE, Lee SJ, Rognmo Ø, Stolen TO, Bye A, Haram PM, Loennechen JP, Al-Share QY, Skogvoll E, Slordahl SA, Kemi OJ, Najjar SM, Wisloff U
    Circulation, 2008-07-07;118(4):346-54.
    Species: Human
    Sample Types: Plasma
  159. Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction.
    Authors: Tamagawa E, Bai N, Morimoto K, Gray C, Mui T, Yatera K, Zhang X, Xing L, Li Y, Laher I, Sin DD, Man SF, van Eeden SF
    Am. J. Physiol. Lung Cell Mol. Physiol., 2008-05-09;295(1):L79-85.
    Species: Rabbit
    Sample Types: Serum
  160. Acute onset human atrial fibrillation is associated with local cardiac platelet activation and endothelial dysfunction.
    Authors: Akar JG, Jeske W, Wilber DJ
    J. Am. Coll. Cardiol., 2008-05-06;51(18):1790-3.
    Species: Human
    Sample Types: Plasma
  161. Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor.
    Authors: Tiwari S, Sharma N, Gill PS, Igarashi P, Kahn CR, Wade JB, Ecelbarger CM
    Proc. Natl. Acad. Sci. U.S.A., 2008-04-18;105(17):6469-74.
    Species: Mouse
    Sample Types: Urine
  162. Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis.
    Authors: Basso AS, Frenkel D, Quintana FJ, Costa-Pinto FA, Petrovic-Stojkovic S, Puckett L, Monsonego A, Bar-Shir A, Engel Y, Gozin M, Weiner HL
    J. Clin. Invest., 2008-04-01;118(4):1532-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  163. Role of extracellular signal-regulated kinases (ERK) in leptin-induced hypertension.
    Authors: Wojcicka G, Jamroz-Wisniewska A, Widomska S, Ksiazek M, Beltowski J
    Life Sci., 2007-12-17;82(7):402-12.
    Species: Rat
    Sample Types: Plasma
  164. The role of caveolin-1 in PCB77-induced eNOS phosphorylation in human-derived endothelial cells.
    Authors: Lim EJ, Smart EJ, Toborek M, Hennig B
    Am. J. Physiol. Heart Circ. Physiol., 2007-10-12;293(6):H3340-7.
    Species: Porcine
    Sample Types: Cell Culture Supernates
  165. Effects of atorvastatin therapy on hypercholesterolemic rabbits with respect to oxidative stress, nitric oxide pathway and homocysteine.
    Authors: Bolayirli IM, Aslan M, Balci H, Altug T, Hacibekiroglu M, Seven A
    Life Sci., 2007-05-06;81(2):121-7.
    Species: Rabbit
    Sample Types: Serum
  166. Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo.
    Authors: Joussen AM, Poulaki V, Qin W, Kirchhof B, Mitsiades N, Wiegand SJ, Rudge J, Yancopoulos GD, Adamis AP
    Am. J. Pathol., 2002-02-01;160(2):501-9.
    Species: Rat
    Sample Types: Tissue Homogenates

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Reviews for Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit

Average Rating: 3.8 (Based on 6 Reviews)

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Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit
By Anonymous on 09/18/2022
Sample Tested: Cell culture supernatant

Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit
By Anonymous on 10/19/2020
Sample Tested: Cell culture supernatant

Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit
By Anonymous on 03/12/2019
Sample Tested: THP-1 human acute monocytic leukemia cell line

***Bio-Techne Response: Thank you for reviewing our product. We are sorry to hear that this antibody did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction.***


Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit
By Anonymous on 02/26/2019
Sample Tested: Cell culture supernatant

Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit
By Danlee Enzler on 04/02/2018
Sample Tested: Cell Culture Media

Total Nitric Oxide and Nitrate/Nitrite Parameter Assay Kit
By Anonymous on 08/23/2016
Sample Tested: Human serum

I did spike in study for both nitrite and nitrate assay. The recovery of Nitrite is very good. However the nitrate is very poor.