Equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. Selective agonist for metabotropic glutamate receptors; active at both group I and group II mGlu receptors (EC50
values are 2, 15, 23 and ~800 μ
M at mGluR2
(Cat. No. 0284) and cis-ACPD
(Cat. No. 0186) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Molecular diversity of glutamate receptors and implications for brain functions.
Metabotropic glutamate receptors: novel targets for drug development.
Knopfel et al.
The metabotropic glutamate receptors: structure and functions.
Pin and Duvoisin
Synthesis and pharmacology of 3-hydroxy-Δ2-isoxazoline-cyclopentance analogues of glutamic acid
Conti et al.
The citations listed below are publications that use Tocris products. Selected citations for (±)-trans-ACPD include:
Showing Results 1 - 6 of 6