Tranylcypromine hydrochloride

Catalog # Availability Size / Price Qty
Tranylcypromine hydrochloride | CAS No. 1986-47-6 | Monoamine Oxidase (MAO) Inhibitors
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Description: Irreversible inhibitor of LSD1; also inhibits MAO
Alternative Names: 2-PCPA

Chemical Name: (±)-trans-2-Phenylcyclopropylamine hydrochloride

Purity: ≥98%

Product Details
Citations (8)

Biological Activity

Tranylcypromine hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Inhibits histone demethylation. In combination with CHIR 99021 (Cat. No. 4423), enables reprogramming of mouse embryonic fibroblasts transduced by only two factors, Oct4 and Klf4, into induced pluripotent stem (iPS) cells.

For more information about how Tranylcypromine hydrochloride may be used, see our protocol: Highly Efficient Generation of CiPSCs from MEFs

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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