TROVE2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-86998

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunoprecipitation

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all TROVE2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGF

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TROVE2 Antibody - BSA Free

Western Blot: TROVE2 Antibody [NBP1-86998]

Western Blot: TROVE2 Antibody [NBP1-86998]

TROVE2-Antibody-Western-Blot-NBP1-86998-img0004.jpg
Immunohistochemistry-Paraffin: TROVE2 Antibody [NBP1-86998]

Immunohistochemistry-Paraffin: TROVE2 Antibody [NBP1-86998]

Immunohistochemistry-Paraffin: TROVE2 Antibody [NBP1-86998] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
TROVE2 Antibody - BSA Free Western Blot: TROVE2 Antibody - BSA Free [NBP1-86998]

Western Blot: TROVE2 Antibody - BSA Free [NBP1-86998]

Analysis in human cell line K562.
TROVE2 Antibody - BSA Free

Western Blot: TROVE2 Antibody - BSA Free [NBP1-86998] -

Ro60 and La proteins are depressed in RRMS. (A) Ro60 (TROVE2) and La (SSB) transcript levels in CTRL (N = 24), CIS-MS (N = 16), RRMS (N = 22), RA (N = 18), SLE (N = 24), NMO (N = 22), and PD (N = 19) were determined by quantitative PCR after cDNA synthesis using oligo-dT. Results are normalized to CTRL = 1.0 after normalization to transcript levels of GAPDH, error bars are S.D. (B) As in (A) using whole genome RNA-sequencing data. (C) Western blotting to determine Ro60 and La protein levels in PBMC from CTRL (N = 9) and RRMS (N = 8). (D) Quantitative estimates of protein abundance relative to beta -actin. *P <0.05, **P <0.01. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/25885816), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Applications for TROVE2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
Use in immunprecipitation reported in scientific literature (PMID 25885816). TROVE2 antibody validated for WB from a verified customer review. For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 1 review rated 5 using NBP1-86998 in the following applications:

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TROVE2

RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation

Alternate Names

60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, 60 kDa SS-A/Ro ribonucleoprotein, Ro 60 kDa autoantigen, RO60gastric cancer multi-drug resistance protein, RORNP, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro), SS-A, SSA2Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro), TROVE domain family member 2, TROVE domain family, member 2

Gene Symbol

RO60

Additional TROVE2 Products

Product Documents for TROVE2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TROVE2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for TROVE2 Antibody - BSA Free

Customer Reviews for TROVE2 Antibody - BSA Free (1)

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Customer Images

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  • Name: Charles Spurlock
    Application: Western Blot
    Sample Tested: Human PBMC Whole Cell Lysate
    Species: Human
    Verified Customer | Posted 06/30/2014
    TROVE2 expression in human PBMCs from a healthy donor.
    TROVE2 Antibody - BSA Free NBP1-86998

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