(+)-Tubocurarine chloride

  ( 5 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:2820
Chemical Name:2,3,13a,14,15,16,25,25a,-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-13H-4,6:21,24-dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium chloride hydrochloride
Product Details
Citations (5)
Reviews
Biological Activity
Competitive, non-selective nicotinic acetylcholine receptor antagonist; causes skeletal muscle relaxation. Also a 5-HT3 and GABAA receptor antagonist.
Technical Data
  • M.Wt:
    681.65
  • Formula:
    C37H41ClN2O6.HCl
  • Solubility:
    Soluble to 25 mM in water and to 10 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    57-94-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (+)-Tubocurarine chloride include:

5 Citations: Showing 1 - 5
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  1. Nicotine receptors mediating sensorimotor gating and its enhancement by systemic nicotine.
    Authors: Pinnock Et al.
    BMC Syst Biol  2015;9:30
  2. Re-Emergent Inhibition of Cochlear Inner Hair Cells in a Mouse Model of Hearing Loss.
    Authors: Zachary and Fuchs
    J Neurosci  2015;35:9701
  3. Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors.
    Authors: Freeman Et al.
    Front Behav Neurosci  2013;110:103
  4. Activity-dependent phosphorylation of GABAA receptors regulates receptor insertion and tonic current.
    Authors: Saliba Et al.
    J Biol Chem  2012;31:2937
  5. Allosteric block of KCa2 channels by apamin.
    Authors: Lamy Et al.
    J Neurophysiol  2010;285:27067

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Average Rating: 5 (Based on 1 review)

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Summary

Species Other

Other Experimental Details

Other Experimental Details To emphasize its action mechanism is useful to compare it with 2 mg of Succinylcholine in a chicken model

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