TWISTNB Antibody

Novus Biologicals | Catalog # NBP2-27081

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Equine, Primate

Predicted:

Canine (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

A portion of amino acids 50-128 of human Twistnb was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in chimpanzee, and 94% homologous in rat and dog.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TWISTNB Antibody

Western Blot: TWISTNB Antibody [NBP2-27081]

Western Blot: TWISTNB Antibody [NBP2-27081]

Western Blot: TWISTNB Antibody [NBP2-27081] - Analysis of TWISTNB in Hela cell lysate in the 1) absence and2) presence of immunizing peptide, and 3) mouse embryo body lysate using this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for TWISTNB Antibody

Application
Recommended Usage

Western Blot

3-5ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TWISTNB

DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb) belongs to the eukaryotic RPA43 RNA polymerase subunit family. It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Twistnb is the component of RNA polymerase I which synthesizes ribosomal RNA precursors. It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. Twist genes are essential for embryonic development and are conserved from jellyfish to human.

Alternate Names

DNA-directed RNA polymerase I subunit RPA43, TWIST neighbor, Twist neighbor protein

Gene Symbol

TWISTNB

UniProt

Additional TWISTNB Products

Product Documents for TWISTNB Antibody

Certificate of Analysis

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Product Specific Notices for TWISTNB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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