U 46619

Catalog # Availability Size / Price Qty
1932/1
U 46619 | CAS No. 56985-40-1 | Prostanoid Receptor Agonists
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Description: Potent, stable thromboxane A2 (TP) receptor agonist
Alternative Names: 9,11-Dideoxy-9a,11a-methanoepoxy prostaglandin F2a

Chemical Name: (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid

Purity: ≥98%

Product Details
Citations (9)
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Biological Activity

PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM). Potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. Activates ERK-1 and ERK-2 in HEK 293 cells expressing TPα and TPβ receptors.

Technical Data

M.Wt:
350.5
Formula:
C21H34O4
Solubility:
Soluble in methyl acetate (supplied pre-dissolved -10mg/ml)
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
56985-40-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for U 46619

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9 Citations: Showing 1 - 9

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