ULK1 Antibody (RM488)

Novus Biologicals | Catalog # NBP3-23466

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM488 expressed in HEK293
View all ULK1 Primary Antibodies »

Product Specifications

Immunogen

A phospho-peptide corresponding to human ULK1 [Ser757] (Uniprot#: O75385)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ULK1 Antibody (RM488)

ULK1 Antibody (RM488)

Western Blot: ULK1 Antibody (RM488) [NBP3-23466] -

Western Blot: ULK1 Antibody (RM488) [NBP3-23466] - Western Blot of the lysates of A431 cells nontreated (-) or treated (+) with Calyculin A/Okadaic Acid, using Clone RM488) at a 1:1000 dilution.

Applications for ULK1 Antibody (RM488)

Application
Recommended Usage

Western Blot

1:1000 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ULK1

ULK1 belongs to the serine/threonine protein kinase family. It is involved in axon growth and plays an essential role in neurite branching during sensory axon outgrowth. Knockdown of ULK1 results in impaired endocytosis of nerve growth factor (NGF), excessive axon arborization, and severely stunted axon elongation indicating that ULK1 mediates a non clathrin coated endocytosis in sensory growth cones. Knockdown of ULK1 also inhibits the autophagic response. It appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy related (Atg) proteins.

Long Name

Serine/threonine-protein kinase ULK1

Alternate Names

ATG1, hATG1, KIAA0722

Gene Symbol

ULK1

Additional ULK1 Products

Product Documents for ULK1 Antibody (RM488)

Certificate of Analysis

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Product Specific Notices for ULK1 Antibody (RM488)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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