VASP Antibody

Novus Biologicals | Catalog # NBP2-42515

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Canine (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all VASP Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RKVSKQEEASGGPT corresponding to internal region according to NP_003361.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for VASP Antibody

Western Blot: VASP Antibody [NBP2-42515]

Western Blot: VASP Antibody [NBP2-42515]

Western Blot: VASP Antibody [NBP2-42515] - (1ug/ml) staining of Mouse Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: VASP Antibody [NBP2-42515]

Western Blot: VASP Antibody [NBP2-42515]

Western Blot: VASP Antibody [NBP2-42515] - (0.01ug/ml) staining of Human Platelets lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for VASP Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

1-3ug/ml
Application Notes
Approx 50kDa band observed in Human Platelets lysates (calculated MW of 39.8kDa according to NP_003361.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Reinhard et al, EMBO J. 1992 Jun;11(6):2063-70. PMID: 1318192). Recommended concentration: 0.01-0.03ug/ml. Approx 40kDa band observed in Mouse Thymus lysates (calculated MW of 39.7kDa according to NP_033525.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: VASP

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in Wiskott-Aldrich syndrome (WAS) patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.

Long Name

Vasodilator-stimulated Phosphoprotein

Alternate Names

vasodilator-stimulated phosphoprotein

Entrez Gene IDs

7408 (Human)

Gene Symbol

VASP

Additional VASP Products

Product Documents for VASP Antibody

Certificate of Analysis

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Product Specific Notices for VASP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Platelet Markers

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