VASP Antibody

Novus Biologicals | Catalog # NBP2-42516

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all VASP Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EKTPKDESANQEEP corresponding to internal region according to NP_003361.1.

Specificity

This antibody is expected to recognize.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for VASP Antibody

Western Blot: VASP Antibody [NBP2-42516]

Western Blot: VASP Antibody [NBP2-42516]

Western Blot: VASP Antibody [NBP2-42516] - Staining of Human Platelets lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for VASP Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:1000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 50 kDa band observed in human platelets lysates is reported in scientific literature (PMID: 1318192).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: VASP

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in Wiskott-Aldrich syndrome (WAS) patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.

Long Name

Vasodilator-stimulated Phosphoprotein

Alternate Names

vasodilator-stimulated phosphoprotein

Entrez Gene IDs

7408 (Human)

Gene Symbol

VASP

Additional VASP Products

Product Documents for VASP Antibody

Certificate of Analysis

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Download SDS

Product Specific Notices for VASP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Platelet Markers

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