Villin 1 Antibody (1D2C3)

Novus Biologicals | Catalog # NBP3-45108

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1D2C3
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Product Specifications

Immunogen

Raised against purified full length native Villin of chicken origin

Specificity

Villin is One of the gelsolin family of calcium regulated actin binding proteins. Normally expressed in the brush border of epithelial cells lining the gastrointestinal tract, hepatobiliary tract and renal proximal convoluted tubules. In colorectal carcinoma, villin is highly expressed. In practice, villin can be included in the panel used for metastatic carcinoma to detect colorectal origin.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Villin 1 Antibody (1D2C3)

Villin 1 Antibody (1D2C3)

Immunohistochemistry-Paraffin: Mouse Villin 1 mAb (1D2C3) [NBP3-45108]

Formalin fixed paraffin embedded human Colorectal carcinoma stained with Villin 1.

Applications for Villin 1 Antibody (1D2C3)

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), Tween-20, 0.2% BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Villin 1

Villin 1 encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq]

Alternate Names

D2S1471, VIL, villin 1, villin-1

Gene Symbol

VIL1

Additional Villin 1 Products

Product Documents for Villin 1 Antibody (1D2C3)

Certificate of Analysis

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Product Specific Notices for Villin 1 Antibody (1D2C3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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