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2 results for "11 beta-HSD Inhibitors Small Molecules and Peptides" in Products
11 beta-HSD Inhibitors Small Molecules and Peptides
The isozymes 11β-HSD1 and 11β-HSD2, both 11β-Hydroxysteroid Dehydrogenases (11β-HSD), catalyze the interconversion of cortisol (corticosterone in rodents) and cortisone (11-dehyrodocorticosterone). 11β-HSD1 converts cortisone to cortisol, the active hormone; and 11β-HSD2 converts cortisol to cortisone, the inactive form.
Cortisol is initially synthesized and released by the adrenal glands under the strict control of adrenocorticotrophic hormone (ACTH). Levels vary ...
| Chemical Name: | (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium |
| Purity: | ≥98% |
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| Chemical Name: | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide |
| Purity: | ≥98% |
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