2 results for "5-HT7 Receptor Antagonists" in Products

5-HT7 Receptor Antagonists

The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. This isoform (A) is the predominant isoform in spleen, caudate and hippocampus. 5-HT7 isoform B is expressed at lower levels. 5-HT7 belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in a...

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Potent and selective 5-HT7 antagonist; brain penetrant

Chemical Name: (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine hydrochloride
Purity: ≥98%
Potent and selective 5-HT7 antagonist; brain penetrant
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High affinity and selective 5-HT7 antagonist; orally bioavailable

Chemical Name: 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride
Purity: ≥98%
High affinity and selective 5-HT7 antagonist; orally bioavailable
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